Effect of mibefradil on left ventricular diastolic function in patients with congestive heart failure

Journal of Cardiovascular Pharmacology

Volumn 27, Issue 5, 1996, Pages 652-656

  Muntinga, H J ^a   Van Der Vring, J A F M ^a   Niemeyer, M G ^a,b   Van Den Berg, F ^a   Knol, H R ^c   Bernink, P J L M ^a   Van Der Wall, E E ^b   Blanksma, P K ^d   Lie, K I ^d  

^a MARTINI HOSPITAL   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Calcium antagonists; Diastolic function; Heart failure; Mibefradil

Indexed keywords

CALCIUM ANTAGONIST; ERYTHROCYTE TC 99M; MIBEFRADIL; PERTECHNETIC ACID TC 99M; PLACEBO;

ADULT; AGED; ANGIOGRAPHY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLE; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FILLING; HEART LEFT VENTRICLE FUNCTION; HEART RATE; HEART STROKE VOLUME; HUMAN; MALE; MEAN ARTERIAL PRESSURE; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE;

ADULT; AGED; BENZIMIDAZOLES; CALCIUM CHANNEL BLOCKERS; DIASTOLE; DOUBLE-BLIND METHOD; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; MALE; MIBEFRADIL; MIDDLE AGED; TETRAHYDRONAPHTHALENES; VENTRICULAR FUNCTION, LEFT;

EID: 0029991017     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199605000-00006     Document Type: Article

References (21)

1. Gaasch WH, Blaustein AS, Le Winter MM. Heart failure and clinical disorders of left ventricular diastolic function. In: Gaasch WH, LeWinter MM, eds. Left ventricular diastolic dysfunction and heart failure. Philadelphia: Lea & Febiger, 1994;245-58.
2. Lahiri A, Rodrigues EA, Carboni GP, Raftery EB. Effects of long-term treatment with calcium antagonists on left ventricular diastolic function in stable angina and heart failure. Circulation 1990;81 (suppl III):130-8.
3. Packer M. Abnormalities of diastolic function as a potential cause of exercise intolerance in chronic heart failure. Circulation 1990; 81(suppl III):78-86.
4. Grossman W. Diastolic dysfunction in congestive heart failure. N Engl J Med 1991;325:1557-64.
5. Bonow RO, Udelson JE. Left ventricular diastolic dysfunction as a cause of congestive heart failure. Mechanisms and management. Ann Intern Med 1992;117:502-10.
6. Elkayam U, Amin J, Anilkumar M, Vasquez J, Weber L, Rahimtoola SH. A prospective, randomized, double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their combination in the treatment of chronic congestive heart failure. Circulation 1990; 82:1954-61.
7. Packer M. Pathophysiological mechanisms underlying the adverse effects of calcium channel-blocking drugs in patients with chronic heart failure. Circulation 1989;80(suppl IV):IV-59-67.
8. Elkayam U, Shotan A, Mehra A, Ostrzega E. Calcium channel blockers in heart failure. J Am Coll Cardiol 1993;22(suppl A): 139A-44A.
9. Dienstl F, Motro M, Poole Wilson PA, et al. Improved diastolic function with the calcium antagonist nisoldipine (coat-core) in patients post myocardial infarction: results of the DEFIANT study. Eur Heart J 1992;13:1496-505.
10. Portegies MCM, Schmitt R, Kraay CJ, et al. Lack of negative inotropic effects of the new calcium antagonist Ro 40-5967 in patients with stable angina pectoris. J Cardiovasc Pharmacol 1991;18:746-51.
11. Vúniant M, Clozel JP, Hess P, Wolfgang R. Ro 40-5967, in contrast to diltiazem, does not reduce left ventricular contractility in rats with chronic myocardial infarction. J Cardiovasc Pharmacol 1991;17:277-84.
12. Juni JE, Chen CC. Effects of gating modes on the analysis of left ventricular function in the presence of heart rate variation. J Nucl Med 1988;29:1272-8.
13. Udelson JE, Bonow RO. Radionuclide angiographic evaluation of left ventricular diastolic function. In: Gaasch WH, LeWinter MM, eds. Left ventricular diastolic dysfunction and heart failure. Philadelphia: Lea & Febiger, 1994;167-91.
14. Bacharach SL, Green MV, Vitale D, et al. Optimum Fourier filtering of cardial data: a minimum-error method [Concise Communication]. J Nucl Med 1983;24:1176-84.
15. Levine HJ, Gaasch WH. Clinical recognition and treatment of diastolic dysfunction and heart failure. In: Gaasch WH, LeWinter MM, eds. Left ventricular diastolic dysfunction and heart failure. Philadelphia: Lea & Febiger, 1994;439-54.
16. Bonow RO. Radionuclide angiographic evaluation of left ventricular diastolic function. Circulation 1991;84(suppl I):I-208-15.
17. Lee KJ, Southee AE, Bautovich GJ, et al. Normalised radionuclide measures of left ventricular diastolic function. Eur J Nucl Med 1989;15:123-7.
18. Bonow RO, Bacharach SL, Crawford-Green C, Green MV. Influence of temporal smoothing on quantitation of left ventricular function by gated blood pool scintigraphy. Am J Cardiol 1989;64: 921-5.
19. Bonow RO, Kent KM, Rosing DR, et al. Improved left ventricular diastolic filling in patients with coronary artery disease after percutaneous transluminal coronary angioplasty. Circulation 1982;66: 1159-67.
20. Lawson WE, Seifert F, Anagnostopoulos C, Hills DJ, Swinford RD, Cohn PF. Effect of coronary artery bypass grafting on left ventricular diastolic function. Am J Cardiol 1988;61:283-7.
21. Clozel JP, Banken L, Osterrieder W. Effects of Ro 40-5967, a novel calcium antagonist, on myocardial function during ischemia induced by lowering coronary perfusion pressure in dogs: comparison with verapamil. J Cardiovasc Pharmacol 1989;14:713-21.