Can software be used to predict antigenic regions in Plasmodium falciparum peptides?

Parasite Immunology

Volumn 18, Issue 3, 1996, Pages 159-161

  Ferreira Da Cruz, Maria De Fátima ^a   Giovanni De Simone, Salvatore ^b,c   Banic, Dalma Maria ^a,d   Canto Cavalheiro, Marilene ^a   Camus, Daniel ^d   Daniel Ribeiro, Claudio Tadeu ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^d INSERM   (France)

Author keywords

malaria; P. falciparum; p126 antigen; peptides

Indexed keywords

PARASITE ANTIGEN; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; COMPUTER PROGRAM; ENZYME LINKED IMMUNOSORBENT ASSAY; MALARIA; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

PLASMODIUM FALCIPARUM;

EID: 0029990110     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.1996.d01-62.x     Document Type: Article

References (13)

1. Atassi M.Z. (1984) Antigenic structures of proteins. Their determination has revealed important aspects of immune recognition and generated strategies for synthetic mimicking of protein binding sites. European Journal of Biochemistry 145, 1-20
2. b restriction of the immune response to the p126 Plasmodium falciparum antigen. Clinical and Experimental Immunology 95, 472-478
3. Chou P.Y. & Fasman G.D. (1974) Prediction of protein conformation. Biochemistry 13, 222-245
4. Debrabant A., Maes P., Delplace P., Dubremetz J.F., Tartar A. & Camus D. (1992) Intramolecular mapping of Plasmodium falciparum p126 proteolytic fragments by N-terminal amino acid sequencing. Molecular and Biochemical Parasitology 53, 89-96
5. Delplace P., Bhatia A., Cagnard M., et al. (1988) Protein p126: a parasitophorous vacuole associated with the release of Plasmodium falciparum merozoites. Biology of the Cell 64, 215-221
6. Ferreira-da-Cruz M.F., Deslandes D.C., Oliveira-Ferreira J., Montenegro-James S., Tartar A., Druilhe D. & Daniel-Ribeiro C.T. (1995). Antibody responses to Plasmodium falciparum sporozoiteliver and blood-stage synthetic peptides in migrant and autochthonous populations in malaria endemic areas. Parasite 2, 23-29.
7. Gamier J., Osguthorpe D.J. & Robson B. (1978) Analysis of the accuracy and implications for predicting the secondary structure of globular proteins. Journal of Molecular Biology 120, 97-120
8. Geysen H.M., Tainer J.A., Rodda S.J., Mason T.J., Alexander H., Gelzoff E.D. & Lerner R.A. (1987) Chemistry of antibody binding to a protein. Science 235, 1184-1190
9. Jameson B. & Wolf H. (1988) The antigenic index: a novel algorithm for predicting antigenic determinants: Computer Application Bioscience 4, 181-186
10. Knapp B., Hundt E., Enders B. & Kupper H.A. (1992) Protection of Aotus monkeys from malaria infection by immunization with recombinant hybrid proteins. Infection and Immunity 60, 2397-2401
11. Kyte J.G. & Doolittle R.F. (1982) A single method for displaying the hydropathic character of a protein. Journal of Molecular Biology 157, 105-132
12. Modrow S. & Wolf H. (1986) Characterization of two related Epstein-Barr virus-encoded membrane proteins that are differentially expressed in Burkitt lymphoma and in vitro-transformed cell lines. Proceedings of National Academy Sciences, USA 83, 5703-5707
13. Van Regen Mortel M.H.V., Briand, J.P., Muller S. & Plave S. (1988) In Synthetic Polypeptides as Antigens, eds R.H. Burdon & P.H. Van Knippenberg, p. 74. Elsevier Amsterdam, New York, Oxford