Modulatory effects of nitric oxide on baroreflex activation in the brainstem nuclei of rats

Chinese Journal of Physiology

Volumn 39, Issue 1, 1996, Pages 57-62

  Lo, Woan Jen ^a   Liu, Hui Wen ^b   Lin, Hui Ching ^b   Ger, Luo Ping ^a   Tung, Che Se ^b   Tseng, Ching Jiunn ^a,b  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

baroreflex; L arginine; L NAME; L NMMA; nitric oxide; nucleus tractus solitarii

Indexed keywords

ARGININE; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BRAIN STEM; CENTRAL NERVOUS SYSTEM; HEART RATE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRESSOR RESPONSE; RAT;

EID: 0029990008     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Palmer R.M.J., A.G. Ferrige, and S. Moncada. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526, 1987.
2. Knowles R.G., M. Palacios, R.M.J. Palmer, and S. Moncada. Formation of nitric oxide from L-arginine in the central nervous system : A transduction mechanism for stimulation of the soluble guanylate cyclase. Proc. Natl. Acad. Sci. USA. 86: 5159-5162, 1989.
3. Palmer R.M.J., D.S. Ashton, and S. Moncada. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333: 664-666, 1988.
4. Hibbs, J.B., R.R. Taintor, and Z. Vavrin. Macrophage cytotoxicity : Role for L-arginine deaminase and imino nitrogen oxidation to nitrite. Science 235: 473-476, 1987.
5. McCall T.B., N.K. Boughton-Smith, R.M.J. Palmer, B.J.R. Whittle, and S. Moncada. Synthesis of nitric oxide from L-arginine by neutrophils. Biochem. J. 261: 293-296, 1989.
6. Ignarro L.J. Nitric oxide: A novel signal transduction mechanism for transcellular communication. Hypertension 16: 477-483, 1990.
7. Bredt, D.S., and S.H. Snyder. Nitric oxide, a novel neuronal messenger. Neuron 18: 3-11, 1992.
8. Moncada, S., and E.A. Higgs. Endogenous nitric oxide: Physiology, pathology and clinical release. Eur. J. Clin. Invest. 21: 361-374, 1991.
9. Spyer, K.M. Neural organization and control of the baroreceptor reflex. Rev. Physiol. Biochem. Pharmacol. 88: 23-124, 1981.
10. Reis D.J. The brain and hypertension: Reflections on 35 years of inquiry into the neurobiology of the circulation. Circulation 70 (suppl III) : III-31-III-45, 1984.
11. Ma, S., and J.P. Long. Central noradrenergic activity is responsible for nitroglycerin-induced cardiovascular effects in the nucleus tractus solitarii. Brain Res. 559: 297-303, 1991.
12. Ma, S., and J.P. Long. Central noradrenergic activity and the cardiovascular effects of nitroglycerin and amyl nitrite. J. Cardiovasc. Pharmacol. 20: 826-836, 1992.
13. Ma, S., R.B. Felder, M.W. Chapleau, and F.M. Abboud. Effects of nitroglycerin on neuronal activity in the solitay tract nucleus in vivo and in vitro (Abstract). FASEB J. 7: A99., 1993.
14. Lewis, S.J., B. Machado, H. Ohta, J.N. Bates, M.J. Brody, and W.T. Talman. Cardiovascular effects of the EDRF candidate S-nitrosocysteine microinjection into the nucleus tractus solitarius of rats. Fed. Am. Soc. Exp. Biol. J. 5: A1411, 1991.
15. Vincent S.R., and H. Kimura. Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 1992; 46: 755-783.
16. Iadecola, C., P.L. Faris, B.K. Hartman, and X. Xu. Localization of NADPH diaphorase in neurons of the rostral ventral medulla : possible role of nitric oxide in central autonomic regulation of oxygen chemoreception. Brain Res. 603: 173-179, 1993.
17. Anderson, C.R. NADPH diaphorase-positive neurons in the rat spinal cord include a sub-population of autonomic preganglionic neurons. Neurosci. Lett. 139: 280-284, 1992.
18. Anberson, C.R., S.L. Edwards, J.B. Furness, D.S. Bredt, and S.H. Snyder. The distribution of nitric oxide synthase-containing autonomic preganglionic terminals in the rat. Brain Res. 614: 78-85, 1993.
19. Chalmers, J.P. Brain amines and models of experimental hypertension. Circ. Res. 51: 469-480. 1975.
20. Tseng, C.J.,H.Y.Liu,H.C.Lin,L.P. Ger, C. S. Tung, and M.H. Yen. Cardiovascular effects of nitric oxide in the brainstem nuclei of rats. Hypertension 27: 36-42, 1996.
21. G -methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. Circ. Res. 70: 607-611, 1992.
22. Togashi, H., I. Sakuma, M. Yoshioka, T. Kobayashi, H. Yasuda, and T. Kitabatake. A central nervous system action of nitric oxide in blood pressure regulation. J. Pharmacol. Exp. Ther. 262: 343-347, 1992.
23. Tseng, C.J., L.L. Chou, L.P. Ger, and C.S. Tung. Cardiovascular effects of angiotension III in brainstem nuclei of normotensive and hypertensive rats. J. Pharmacol. Exp. Ther. 268: 558-564, 1994.
24. Tseng, C.J., R. Mosqueda-Garcia, M. Appalsamy, and D. Robertson. Cardiovascular effects of neuropeptide Y in rat brainstem nuclei. Circ. Res. 64:55-61, 1989.
25. Reis, D. J., A.R. Granata, M.H. Perrone, and W. Talman. Evidence that glutamic acid is the neurotransmitter of baroreceptor afferents terminating in the nucleus tractus solitarius (NTS). J. Auton. Nerv. Syst. 3: 321-334, 1981.
26. Deng L.Y., G. Thibault, and E.L. Schiffin. Effect of hypertension induced of nitric oxide synthase inhibition on structure and function of resistance arteries in the rat. Clin. Exp. Hypertens. 15: 527-537, 1993.
27. Ribeiro M.O., E. Antunes, G. de Nucci, S.M. Lovisolo, and R. Zatz. Chronic inhibition of nitric oxide synthesis : a new model of arterial hypertension. Hypertension 20: 298-303, 1992.
28. Baylis, C., B. Mitruka, and A. Deng. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J. Clin. Invest. 90: 278-281, 1992.
29. Scrogin, K.E., R. Veelken, and F.C. Luft. Sympathetic baroreceptor responses after chronic NG-nitro-L-Arginine methyl ester treatment in conscious rats. Hypertension 23: 982-986, 1994.
30. Shengxing, M.A., F.M. Abboud, and R.B. Felder. Effects of L-arginine-derived nitric oxide synthesis on neuronal activity in nucleus tractus solitarius. Am. J. Physiol. 268: R487-91, 1995.
31. Paola E.D.D., M.J. Vidal, and G. Nistico. L-Glutamate evokes the release of an endothelium-derived relaxing factor-like substance from the rat nucleus tractus solitarius. J. Cardiovasc. Pharmacol. 17 (suppl 3): S269-S272, 1991.
32. Talman W.T., M.H. Perrone, and D.J. Reis. Evidence for L-glutamate as the neurotransmitter of baroreceptor afferent nerve fibers. Science 209: 813-815, 1980.
33. Talman W.T., A.R. Granata, and D.J. Reis. Glutamatergic mechanisms in the nucleus tractus solitarius in blood pressure control. Fed. Proc. 43: 39-44, 1984.
34. Bredt D.S., and S.H. Snyder. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc. Natl. Acad. Sci. U S A. 86: 9030-9033, 1989.
35. G -nitro-L-arginine methyl ester in conscious Brattelboro rats. Br. J. Pharmacol. 101: 10-12, 1990.