A single dose pharmacokinetic study of 13-cis retinoic acid (Isotretinoin, Ro 04-3780) in the pregnant New Zealand rabbit using intravenous infusion

International Journal of Pharmaceutics

Volumn 134, Issue 1-2, 1996, Pages 157-165

  Huselton, C A ^a   DeGrazia, F ^a   Stahl, E ^a   Liberato, D J ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

13 cis retinoic acid; Intravenous infusion; Pharmacokinetics; Pregnant New Zealand rabbit

Indexed keywords

DRUG METABOLITE; ISOTRETINOIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MATHEMATICAL ANALYSIS; NONHUMAN; PHARMACOKINETICS; PREGNANCY; PRIORITY JOURNAL; RABBIT; TERATOGENESIS;

EID: 0029989748     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)04406-X     Document Type: Article

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