Elemental composition and water content of rat optic nerve myelinated axons during in vitro post-anoxia reoxygenation

Neuroscience

Volumn 73, Issue 4, 1996, Pages 1081-1090

  Stys, P K ^a   Lopachin Jr , R M ^b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

anoxia; Ca2+; electron probe X ray microanalysis; glial cells; Na+ Ca2+ exchanger; reperfusion injury

Indexed keywords

CALCIUM;

ANOXIA; ARTICLE; CALCIUM TRANSPORT; ELECTRON PROBE MICROANALYSIS; GLIA CELL; MYELINATION; OPTIC NERVE; PRIORITY JOURNAL; REOXYGENATION; REPERFUSION INJURY; SODIUM TRANSPORT; WATER CONTENT;

EID: 0029989742     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00114-5     Document Type: Article

References (45)

1. Brody I. A. (1964) Lactate dehydrogenase isoenzymes: a difference between cutaneous and muscular nerves. J. Neurochem. 13, 975-978.
2. Bulger R. E., Beeuwkes R. and Saubermann A. J. (1981) Application of scanning electron microscopy to X-ray analysis of frozen-hydrated sections - III. Elemental content of cells in the rat renal papillary tip. J. Cell Biol. 88, 274-280.
3. Cao W., Carney J. M., Duchon A., Floyd R. A. and Chevion M. (1988) Oxygen free radical involvement in ischemia and reperfusion injury to brain. Neurosci Lett. 88, 233-238.
4. Choi D. W. (1990) Cerebral hypoxia: some new approaches and unanswered questions. J. Neurosci. 10, 2493-2501.
5. DiPolo R. and Beauge L. (1986) Reverse Na-Ca exchange requires internal Ca and/or ATP in squid axons. Biochim. biophys. Acta 854, 298-306.
6. 2+,-dependent phosphorylation. Biochim. biophys. Acta 897, 347-354.
7. +: implications for neurodegeneration. J. Neurochem. 63, 584-591.
8. Farber J. L. (1981) Membrane injury and calcium homeostasis in the pathogenesis of coagulative necrosis. Lab. Invest. 47, 114-123.
9. Fiskum G. (1985) Mitochondrial damage during cerebral ischemia. Ann. Emerg. Med. 14, 810-815.
10. Foster M. C. and Saubermann A. J. (1991) Personal-computer-based system for electron beam X-ray microanalysis of biological samples. J. Microsc. 161, 367-373.
11. Gelfan S. and Tarlov I. M. (1955) Differential vulnerability of spinal cord structures to anoxia. J. Neurophys. 18, 170-188.
12. Gelfan S. and Tarlov I. M. (1956) Physiology of spinal cord, nerve root and peripheral nerve compression. Am. J. Physiol. 185, 217-229.
13. Gerard R. W. (1927) Studies on nerve metabolism - II. Respiration in oxygen and nitrogen. Am. J. Physiol. 82, 381-404.
14. Gunter T. E. and Pfeiffer D. R. (1990) Mechanisms by which mitochondria transport calcium. Am. J. Physiol. 258 (Cell Physiol 27), 755-786.
15. Hall T. A., Anderson H. C. and Appleton T. (1973) The use of thin specimens for X-ray microanalysis in biology. J. Microsc. 99, 177-182.
16. Halliwell B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623.
17. Hansen A. J. (1985) Effect of anoxia on ion distribution in the brain. Physiol. Rev. 65, 101-148.
18. Hori O., Matsumoto M., Maeda Y., Ueda H., Ohtsuki T., Stern D. M., Kinoshita T., Ogawa S. and Kamada T. (1994) Metabolic and biosynthetic alterations in cultured astrocytes exposed to hypoxia/reoxygenation. J. Neurochem. 62, 1489-1495.
19. Kim-Lee M. H., Stokes B. T. and Yates A. J. (1992) Reperfusion paradox: a novel mode of glial cell injury. Glia 5, 56-64.
20. Lehning E. J., Stys P. K. and LoPachin R. M. (1996) Reoxygenation of anoxic peripheral nerve myelinated axons promotes re-establishment of normal elemental composition. Brain Res. In press.
21. LoPachin R. M., Castiglia C. M. and Saubermann A. J. (1991) Elemental composition and water content of myelinated axons and glial cells in rat central nervous system. Brain Res. 549, 253-259.
22. LoPachin R. M., Castiglia C. M. and Saubermann A. J. (1992) Perturbation of axonal elemental composition and water content: implications for neurotoxic mechanisms. Neurotoxicology 13, 123-138.
23. LoPachin R. M., Castiglia C. M. and Saubermann A. J. (1992) Acrylamide disrupts elemental composition and water content of rat tibial nerve - II. Schwann cells and myelin. Tox. appl. Pharmac. 115, 35-43.
24. LoPachin R. M., Castiglia C. M., Saubermann A. J. and Eichberg J. (1993) Ganglioside treatment modifies abnormal elemental composition in peripheral nerve myelinated axons of experimentally diabetic rats. J. Neurochem. 60, 477-486.
25. LoPachin R. M., LoPachin V. and Saubermann A. (1990) Effects of axotomy on distribution and concentration of elements in rat sciatic nerve. J. Neurochem. 54, 320-332.
26. LoPachin R. M., Lowery J., Eichberg J., Kirkpatrick J. B., Cartwright J. and Saubermann A. J. (1988) Distribution of elements in rat peripheral axons and nerve cell bodies determined by X-ray microprobe analysis. J. Neurochem. 51, 764-775.
27. LoPachin R. M. and Saubermann A. J. (1990) Disruption of cellular elements and water in neurotoxicity studies using electron probe X-ray microanalysis. Tox. appl. Pharmac. 106, 355-374.
28. LoPachin R. M. and Stys P. K. (1995) Elemental composition and water content of rat optic nerve myelinated axons and glial cells: effects of in vitro anoxia and reoxygenation. J. Neurosci. 15, 6735-6746.
29. McCord J. M. and Turrens J. F. (1994) Mitochondrial injury by ischemia and reperfusion. In Current Topics in Bioenergetics, Vol. 17, pp. 173-195. Academic Press, San Diego.
30. Nicholls D. G. (1985) A role for the mitochondrion in the protection of cells against calcium overload? In Progress in Brain Research (eds Kogure K., Hossmann K. A., Siesjo K. and Welsh F. A.), Vol. 63, pp. 97-106. Elsevier, Amsterdam.
31. Nicholls D. G. and Akerman K. (1982) Mitochondrial calcium transport. Biochim. biophys. Acta 683, 57-88.
32. Parry G. J. and Brown M. J. (1982) Selective fiber vulnerability in acute ischemic neuropathy. Ann. Neurol. 11, 147-154.
33. Saubermann A. J., Beeuwkes R. and Peters P. D. (1981) Application of scanning electron microscopy to X-ray analysis of frozen-hydrated sections - II. Analysis of standard solutions and artificial electrolyte gradients. J. Cell Biol. 88, 268-273.
34. Saubermann A. J., Echlin P., Peters P. D. and Beeuwkes R. (1981) Application of scanning electron microscopy to X-ray analysis of frozen-hydrated sections - I. Specimen handling techniques. J. Cell Biol. 88, 257-267.
35. Siesjo B. K. (1981) Cell damage in the brain: a speculative synthesis. J. cerebr. Blood Flow Metab. 1, 155-185.
36. Siesjo B. K. (1988) Mechanisms of ischemic brain damage. Crit. Care Med. 16, 954-963.
37. Stys P. K., Ransom B. R., Waxman S. G. and Davis P. K. (1990) Role of extracellular calcium in anoxic injury of mammalian central white matter. Proc. natl. Acad. Sci. 87, 4212-4216.
38. Stys P. K., Waxman S. G. and Ransom B. R. (1991) Na-Ca exchanger mediates calcium influx during anoxia in mammalian central nervous system white matter. Ann. Neurol. 30, 375-380.
39. Stys P. K., Waxman S. G. and Ransom B. R. (1992) Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na channels and Na-Ca exchanger. J. Neurosci. 12, 430-439.
40. Utzschneider D. A., Kocsis J. D. and Waxman S. G. (1991) Differential sensitivity to hypoxia of the peripheral versus central trajectory of primary afferent axons. Brain Res. 551, 136-141.
41. Waxman S. G., Black J. A., Ransom B. R. and Stys P. K. (1993) Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium. Brain Res. 614, 137-145.
42. Waxman S. G., Black J. A., Stys P. K. and Ransom B. R. (1992) Ultrastructural concomitants of anoxic injury and early post-anoxic recovery in rat optic nerve. Brain Res. 574, 105-119.
43. Young W. (1986) Ca paradox in neural injury: a hypothesis. Cent. Nerv. Syst. Trauma 3, 235-251.
44. Zoccarato F. and Nicholls D. G. (1982) The role of phosphate in the regulation of the calcium efflux pathway of liver mitochondria. Eur. J. Biochem. 127, 333-338.
45. Zollman P. A., Awad O., Schmelzer J. D. and Low P. A. (1991) Effects of ischemia and reperfusion in vivo on energy metabolism of rat sciatic-tibial and caudal nerves. Exp. Neurol. 114, 315-320.