Mifepristone (RU 486) and its incidence on amniotic fluid volume in near term fetal macaque monkeys

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 66, Issue 2, 1996, Pages 179-182

  Haddad, B ^a   Germain, G ^b   Cabrol, D ^c  

^a CENTRE HOSPITALIER INTERCOMMUNAL DE CRÉTEIL   (France)

^b CEMAGREF   (France)

^c Institut Cochin   (France)

Author keywords

Amniotic fluid volume; Macaque monkey; Mifepristone; Pregnancy

Indexed keywords

MIFEPRISTONE; NIFEPRISTONE; PLACEBO; UNCLASSIFIED DRUG;

AMNION FLUID; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FETUS; INTRAMUSCULAR DRUG ADMINISTRATION; MONKEY; NONHUMAN; PREGNANCY; PRIORITY JOURNAL;

EID: 0029988815     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/0301-2115(96)02415-3     Document Type: Article

References (18)

1. Silvestre L, Dubois C, Renault M, Rezvani Y, Beaulieu EE, Ulmann A. Volontary interruption of pregnancy with Mifepristone (RU 486) and a prostaglandin analogue: a large-scale French experience. N Engl J Med 1990; 322: 645-648.
2. Ulmann A, Sylvestre L. RU 486: the French experience. Hum Reprod 1994; 9: 126-130.
3. Urquhart DR, Templeton AA. Mifepristone (RU 486) and second trimester termination. Lancet 1987; ii: 1405.
4. [41 Rodger MW, Baird DT. Pretreatment with Mifepristone (RU 486) reduces interval between prostaglandin administration and expulsion in second trimester abortion. Br J Obstet Gynaecol 1990; 97: 41-45.
5. Cabrol D, Dubois C, Cronje H, Gonnet JM, Guillot M, Maria B, Moodley J, Oury JF, Thoulon JM, Treisser A, Ulmann D, Correl S, Ulmann A. Induction of labor with Mifepristone (RU 486) in intrauterine fetal death. Am J Obstet Gynecol 1990; 163: 540-542.
6. Lelaidier C, Baton C, Benifla JL, Fernandez H, Bourget P, Frydman R. Mifepristone for labour induction after previous caesarean section. Br J Obstet Gynaecol 1994; 101: 501-503.
7. Cabrol D, Germain G. Why we should not use Mifepristone (RU 486) to induce labor in normal pregnancies at term? [abstract]. Internat J Gynecol Obstet 1994; 46: DB09.5.
8. Haluska GJ, Stanczyk FZ, Cook MJ, Novy MJ. Temporal changes in uterine activity and prostaglandin response to RU 486 in rhesus macaques in late gestation. Am J Obstet Gynecol 1987; 157: 1487-1495.
9. Haluska GJ, West NB, Novy MJ, Brenner RM. Uterine estrogen receptors are increased by RU 486 in late pregnant rhesus macaques but not after spontaneous labor. J Clin Endocrinol Metab 1990; 70: 181-186.
10. Haluska GJ, Kaler CA, Cook MJ, Novy MJ. Prostaglandin production during spontaneous labor and after treatment with RU 486 in pregnant rhesus macaques. Biol Reprod 1994; 51: 760-765.
11. Germain G, Philibert D, Pottier J, Mouren M, Beaulieu EE, Sureau C. Effects of the antiprogesterone agent RU 486 on the natural cycle and gestation in intact cynomolgus monkeys. In: Beaulieu EE, Segal SJ, editors. The antiprogestin steroid RU 486 and human fertility control. New York: Plenum Press, 1985; 155-167.
12. Germain G, Leroy MJ, Breuiller-Fouche M. Role of steroids in the onset of labor. In: Garfield RE, Tabb TN, editors. Control of uterine contractility. Boca Raton: CRC Press, 1994; 441.
13. Manning FA, Platt LD, Sipos L. Antepartum fetal evaluation: development of fetal biophysical profile. Am J Obstet Gynecol 1980; 136: 787.
14. Phelan JP, Smith CV, Broussard P, Small M. Amniotic fluid volume assessment with the four-quadrant technique at 36-42 weeks gestation. J Reprod Med 1987; 32: 540-542.
15. Rutherford SE, Phelan JP, Smith CV, Jacobs N. The four-quadrant assessment of amniotic fluid volume: an adjunct to antepartum fetal heart rate testing. Obstet Gynecol 1987; 70: 353-356.
16. Frydman R, Taylor S, Ulmann A. Transplacental passage of Mifepristone. Lancet 1985; ii: 1252.
17. Wolf JP, Chillik CF, Itskovitz J, Weyman D, Anderson TL, Ulmann A, Baulieu EE, Hodgen GD. Transplacental passage of a progesterone antagonist in monkeys. Am J Obstet Gynecol 1988; 159: 238-242.
18. Hill NC, Selinger M, Ferguson J, MacKenzie IZ. Transplacental passage of Mifepristone and its influence on maternal and fetal steroid concentrations in the second trimester of pregnancy. Hum Reprod 1991; 6: 458-462.