Characterization of Na+/H+ exchange activity in cultured rat hippocampal astrocytes

Journal of Neuroscience Research

Volumn 44, Issue 2, 1996, Pages 191-198

  Pizzonia, J H ^a   Ransom, B R ^a   Pappas, C A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

amiloride; antibody; BCECF; EIPA; glia; Na+ H+ exchanger; Western blot

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; AMILORIDE; BICARBONATE; CARRIER PROTEIN; PROTON SODIUM EXCHANGER PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL PH; HIPPOCAMPUS; IMMUNOBLOTTING; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT;

AMILORIDE; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BICARBONATES; CELL MEMBRANE; CELLS, CULTURED; GENE EXPRESSION; HIPPOCAMPUS; HYDROGEN-ION CONCENTRATION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-HYDROGEN ANTIPORTER;

EID: 0029988554     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19960415)44:2<191::AID-JNR12>3.0.CO;2-9     Document Type: Article

References (29)

1. Biemesderfer D, Reilly RF, Exner M, Igarashi P, Aronson PS (1992): Immunocytochemical characterization of Na/H exchanger isoform NHE-1 in rabbit kidney. Am J Physiol 263(Renal Fluid Electrolyte Physiol 32):F833-F840.
2. 3-. Am J Physiol 255(Cell Physiol 24):C844-C856.
3. Boyarsky G, Ransom BR, Schlue WR, Davis MBE, Boron WF (1993): Intracellular pH regulation in single cultured astrocytes from rat forebrain. Glia 8:241-248.
4. + exchanger (NHE-2). Proc Natl Acad Sci USA 90:3938-3942.
5. + exchanger. J Membr Biol 90:1-12.
6. + exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. Biochim Biophys Acta 988:73-97.
7. 1 cell differ in sensitivity to N-ethylisopropylamiloride. J Cell Biol 107:785a.
8. + exchanger transcript. Biochim Biophys Acta 1129: 105-108.
9. Hoffman EK, Simonsen O (1989): Membrane mechanisms in volume and pH regulation in vertebrate cells. Physiol Rev 69:315-382.
10. + exchanger (NHE5/ SLC9A5) to chromosome 16q22.1. Genomics 25:615-622.
11. Kleyman TR, Cragoe EJ (1988): Amiloride and its analogs as tools in the study of ion transport. J Membr Biol 105:1-21.
12. Laemmli UK (1970): Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227:680-685.
13. + antiport abolishes growth factor-induced DNA synthesis in fibroblasts. J Biol Chem 259:4313-4319.
14. Lowry HO, Rosebrough NH, Farr AL, Randall RJ (1951): Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
15. Orlowski J (1993): Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger. J Biol Chem 268:16369-16375.
16. + exchanger gene family. J Biol Chem 267:9331-9339.
17. - -pump in hippocampal astrocytes. Glia 9:280-291.
18. Pappas CA, Ransom BR (1994): Depolarization-induced alkalinization (DIA) in rat hippocampal astrocytes. J Neurophysiol 72: 2816-2826.
19. + exchanger in LLC-PK1 epithelial cells. Am J Physiol 261(Renal Fluid Electrolyte Physiol 30):F1088-F1094.
20. + antiporter. Cell 56:271-280.
21. +-current expression in rat hippocampal astrocytes in vitro: Alterations during development. Neurophysiol 65:3-19.
22. Thomas JA, Buchsbaum RN, Zimniak A. Racker E (1979): Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 81:2210-2218.
23. + exchanger. EMBO J 10:1957-1967.
24. + exchanger isoform NHE3. J Biol Chem 267:9340-9346.
25. + exchanger isoform (NHE3). J Gen Physiol 100:60a.
26. + exchanger isoform (NHE2). J Biol Chem 268:11917-11924.
27. + exchange in various cell types. Biochem Biophys Res Commun 116:86-90.
28. + exchanger. J Biol Chem 268:11925-11928.
29. Wuttke WA, Walz W (1990): Sodium- and bicarbonate-independent regulation of intracellular pH in cultured mouse astrocytes. Neurosci Lett 117:105-110.