Ovary mediates the effects of RU486 given during proestrus on the diestrous secretion of luteinizing hormone in the rat

Biology of Reproduction

Volumn 54, Issue 6, 1996, Pages 1266-1270

  Tébar, María ^a   Ruíz, Antonio ^a   Bellido, Carmen ^a   Sánchez Criado, José E ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; FOLLITROPIN; GONADORELIN; LUTEINIZING HORMONE; MIFEPRISTONE; PROGESTERONE; TESTOSTERONE;

ANIMAL EXPERIMENT; ARTICLE; DRUG EFFECT; ESTROGEN RELEASE; FEMALE; FOLLITROPIN RELEASE; HORMONAL REGULATION; HORMONE ACTION; HYPOPHYSIS; LUTEINIZING HORMONE RELEASE; NONHUMAN; OVARY; PRIORITY JOURNAL; PROESTRUS; PROGESTERONE RELEASE; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TESTOSTERONE RELEASE;

ANIMALIA;

EID: 0029988382     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod54.6.1266     Document Type: Article

References (30)

1. Tébar M, Ruiz A, Gaytán F, Sánchez-Criado JE. Follicular and luteal progesterone play different roles synchronizing pituitary and ovarian events in the 4-day cyclic rat. Biol Reprod 1995; 53:1183-1189.
2. Sánchez-Criado JE, Bellido C, Galiot F, López F, Gaytan F. A possible dual mechanism of the anovulatory action of antiprogesterone RU486 in the rat. Biol Reprod 1990; 42:877-886.
3. Sánchez-Criado JE, Uilenbroek JThJ, de Jong FH. Antiprogesterone RU486 increases serum immunoreactive inhibin levels and LH:FSH and testosterone:oestradiol ratios in cyclic rats. J Endocrinol 1992; 134:51-57.
4. Uchida K, Kadowaki M, Miyake T. Ovarian secretion of progesterone and 20α-hydroxypregn-4-en-3-one during rat estrous cycle in chronological relation to pituitary release of luteinizing hormone. Endocrinol Jpn 1969; 16:227-237.
5. Smith MS, Freeman ME, Neill JD. The control of progesterone secretion during the estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy. Endocrinology 1975; 96:219-226.
6. McGinnis MY, Krey LC, MacLusky NJ, McEwen BS. Characterization of steroid receptor levels in intact and ovariectomized estrogen-treated rats. An examination of the quantitative, temporal, and endocrine factors which influence the neuroendocrine efficacy of an estradiol stimulus, Neuroendocrinology 1981; 33:158-161.
7. Rainbow TC, McGinnis MY, Krey LC. Nuclear progestin receptors in rat brain and pituitary Neuroendocrinology 1982; 34:426-432.
8. Schreiber JR, Erickson GF. Progesterone receptor in the rat ovary: further characterization and localization in the granulosa cell. Steroids 1979; 34:459-469.
9. Park O-K, Mayo K. Transient expression of progesterone receptor messenger RNA in ovarian granulosa cells after the preovulatory luteinizing hormone surge. Mol Endocrinol 1991; 5:967-978.
10. Natraj U, Richards JS. Hormonal regulation, localization, and functional activity of the progesterone receptor in granulosa cells of rat preovulatory follicles. Endocrinology 1993; 133:761-769.
11. Chandolia RK, Weinbauer GF, Fingscheidt U, Bartlett JMS, Nieschlag E, Effects of flutamide on testicular involution induced by an antagonist of gonadotrophin-releasing hormone and on stimulation of spermatogenesis by follicle-stimulating hormone in rats. J Reprod Fertil 1991; 93:313-323.
12. 131-I-labeled human growth hormone of high specific radioactivity. Biochem J 1963; 89:114-123.
13. Gallo RV, Bona-Gallo A. Lack of ovarian steroid negative feedback on pulsatile luteinizing hormone release between estrus and diestrus day 1 in the rat estrous cycle. Endocrinology 1985; 116:1525-1528.
14. Philibert D, Moguilewsky M, Mary I, Lecaque D, Tournemine C, Secchi J, DeRaedt R. Pharmacological profile of RU486 in animals. In: Baulieu EE, Segal SJ (eds.). The Antiprogestins Steroid RU486 and Human Fertility Control. New York: Plenum Press; 1985; 49-68.
15. Baulieu EE. Contragestion and other clinical applications of RU486, an antiprogestagen at the receptor. Science 1989; 245:1351-1357
16. Baulieu EE. The antisteroid RU486: its cellular and molecular mode of action, TEM 1991; 2:233-239.
17. Knox KI., Schwartz NB. RU486 blocks the secondary surge of follicle-stimulating hormone in the rat without blocking the drop in serum inhibin Biol Reprod 1992; 46:220-225.
18. Knox KL, Ringstrom SJ, Schwartz NB RU486 blocks the effects of inhibin or luteinizing hormone on the secondary follicle-stimulating hormone surge. Endocrinology 1993; 133:277-283.
19. Kaneko S, Sato N, Sato K, Hashimoto I. Changes in plasma progesterone, estradiol, follicle-stimulating hormone and luteinizing hormone during diestrus and ovulation in rats with 5-day estrous cycles: effect of antibody against progesterone. Biol Reprod 1986; 3:488-494.
20. Kato J, Onouchi T. Specific progesterone receptors in the hypothalamus and anterior hypophysis of the rat. Endocrinology 1977; 101:920-928.
21. Park-Sarge OK, Parmer TG, Gu Y, Gibori G. The rat corpus luteum does not express progesterone receptors, Biol Reprod 1994: 50(suppl 1): abstract 6.
22. Schreiber JR, Hsueh AJW, Baulieu EE. Binding of the antiprogestin RU486 to rat ovary steroid receptors. Contraception 1983: 28:77-85.
23. Dupon C, Kim MH. Peripheral plasma levels of testosterone, androstenedione and oestradiol during the rat oestrous cycle. J Endocrinol 1973; 59:653-654.
24. Ying SY, Ling N, Böhlen P, Guillemin R. Gonadocrinins: peptide in ovarian follicular fluid stimulating the secretion of pituitary gonadotropins. Endocrinology 1981; 108:1206-1215.
25. de Koning J, Tijssen AMI, van Rees GP. The involvement of ovarian factors in maintaining the pituitary glands of female rats in a state of low LH responsiveness to LHRH. J Endocrinol 1987; 112:265-273.
26. Erickson GF, Magofin DA, Dyer ChA, Hofedits Ch. The ovarian androgen producing cells: a review of structure /function relationship. Endocr Rev 1986; 6:371-399.
27. Drouin J, Labrie F. Selective effect of androgens on LH and FSH release in anterior pituitary cell culture. Endocrinology 1976; 98:1528-1534.
28. Schuiling GA, Moes H, Koiter TR. Interdependence of oestradiol and 5α-dihyclrotestosterone in modulating LH and FSH secretion in rats. J Endocrinol 1989; 126:257-262.
29. Docke F, Rohde P, Gerber P, Chaoui R, Dörner G. Varying sensitivity to the negative oestrogen feedback during the ovarian cycle of female rats: evidence for the involvement of oestrogen and the medial preoptic area. J Endocrinol 1984; 102:287-294.
30. Döcke F, Rohde W, Chaoui R, Stürzebecher J, Dörner G. Retardation of preovulatory desensitization to negative oestrogen feedback: mechanism of the effect of progesterone in 5-day cyclic rats. J Endocrinol 1987; 114:409-414.