In vitro and in vivo growth inhibition of murine melanoma K-1735 cells by a dominant negative mutant α subunit of the Gi2 protein

Cellular Signalling

Volumn 8, Issue 3, 1996, Pages 159-166

  Hermouet, Sylvie ^a,c   Aznavoorian, Sadie ^b   Spiegel, Allen M ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c INSTITUT DE BIOLOGIE   (France)

Author keywords

Gi2 proteins; Malignant cell growth; Melanoma; Tumor formation

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; PROTEIN G; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL MOTILITY; DENATURATION; MELANOMA; MELANOMA CELL; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH;

ANIMALS; CELL DIVISION; CHEMOTAXIS; COLLAGEN; FIBRONECTINS; GENE EXPRESSION; GROWTH INHIBITORS; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEINS; MELANOMA; MICE; MICE, NUDE; MUTATION; NEOPLASM METASTASIS; PROTO-ONCOGENE PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0029988205     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/0898-6568(95)02049-7     Document Type: Article

References (39)

1. Gautam N., Northup J., Tamir H. and Simon M. I. (1990) Proc. Natl. Acad. Sci. USA 87, 7973-7977.
2. Bourne H. R., Sanders D. A. and McCormick F. (1990) Nature 348, 125-132.
3. Bourne H. R., Sanders D. A. and McCormick F. (1991) Nature 349, 117-127.
4. Simon M. I., Strathmann M. P. and Gautam N. (1991) Science 252, 802-808.
5. Spiegel A. M., Shenker A. and Weinstein L. S. (1992) Endocr. Rev. 13, 1-30.
6. Tang W.-J. and Gilman A. G. (1991) Science 254, 1500-1503.
7. Camps M., Carozzi A., Schnabel P., Scheer A., Parker P. J. and Gierschik, P. (1992) Nature 360, 684-686.
8. Kameyama K., Haga K., Kontani K., Katada T. and Fukada Y. (1993) J. Biol. Chem. 268, 7753-7758.
9. Kalinec G., Nazarali A. J., Hermouet S., Xu N. and Gutkind J. S. (1992) Mol. Cell. Biol. 12, 4687-4693.
10. Xu N., Bradley L., Ambdukar I. and Gutkind J. S. (1993) Proc. Natl. Acad. Sci. USA 90, 6741-6745.
11. Pace A. M., Wong Y. H. and Bourne H. R. (1991) Proc. Natl. Acad. Sci. USA 88, 7031-7035.
12. Hermouet S., Merendino J. J., Jr., Gutkind J. S. and Spiegel A. M. (1991) Proc. Natl. Acad. Sci. USA 88, 10455-10459.
13. Lyons J., Landis C. A., Harsh G. Vallar L., Grünewald K., Feichtinger H., Duh Q.-Y., Clark O. H., Kawasaki E., Bourne H. R. and McCormick F. (1990) Science 249, 655-659.
14. Murayama T. and Ui M. (1987) J. Biol. Chem. 262, 12463-12467.
15. Koyasu S., Miyajima A., Arai K., Okajima F., Ui M. and Yahara I. (1989) Cell Struct. Funct. 14, 459-471.
16. Masuda N. and Ui M. (1991) FEBS Lett. 291, 9-12.
17. Moxham C. M., Hod Y. and Malbon C. C. (1993) Science 260, 991-995.
18. Rudolph U., Finegold M. J., Rich S. S. et al. (1995) Nature Genetics 10, 143-150.
19. Fidler I. J., Gruys E., Cifone M. A., Barnes Z. and Bucana C. (1981) J. Natl. Cancer Inst. 67, 947-956.
20. Leone A., Flatow U., King C. R. et al. (1991) Cell 65, 25-35.
21. Lester B. R., Weinstein L. S., McCarthy J. B., Sun Z., Smith R. S. and Furcht L. T. (1991) Int. J. Cancer 48, 113-120.
22. Roos E. and Van de Pavert H. V. (1987) Cancer Res. 47, 5439-5444.
23. Lester B. R., McCarthy J. B., Sun Z. Q., Smith R. S., Furcht L. T. and Spiegel A. M. (1989) Cancer Res. 49, 5940-5948.
24. Graziano M. P. and Gilman A. G. (1989) J. Biol. Chem. 264, 15475-15482.
25. Masters S. B., Miller R. T., Chi M. H. et al. (1989) J. Biol. Chem. 264, 15467-15474.
26. Miller R. T., Masters S. B., Sullivan K. A., Beiderman B. and Bourne H. R. (1988) Nature 334, 712-715.
27. Osawa S. and Johnson G. L. (1991) J. Biol. Chem. 266, 4673-4676.
28. Lee E., Taussig R. and Gilman A. G. (1992) J. Biol. Chem. 267, 1212-1218.
29. Gupta S. K., Gallego C., Lowndes J. M. et al. (1992) Mol. Cell. Biol. 12, 190-197.
30. Bradford M. M. (1976) Anal. Biochem. 72, 248-254.
31. Goldsmith P., Gierschik P., Milligan G. et al. (1987) J. Biol. Chem. 262, 14683-14688.
32. Murakami T., Simonds W. F. and Spiegel A. M. (1992) Biochemistry 31, 2905-2911.
33. Stracke M. L., Krutzsch H. C., Unsworth E. J. et al. (1992) J. Biol. Chem. 267, 2524-2529.
34. Aznavoorian S., Stracke M. L., Krutzsch H., Schiffman E. and Liotta L. A. (1990) J. Cell Biol. 110, 1427-1438.
35. Polakis P. G., Uhing R. J. and Snyderman R. (1988) J. Biol. Chem. 263, 4969-4976.
36. Rollins T. E., Siciliano S., Kobayashi S. et al. (1991) Proc. Natl. Acad. Sci. USA 88, 971-975.
37. Crespo P., Ningzhi X., Simonds W. F. and Gutkind J. S. (1994) Nature 369, 418-420.
38. Fanure M., Voyno-Yasenetskaya T. A. and Bourne H. R. (1994) J. Biol. Chem. 269, 7851-7854.
39. Spiegel A. M., Weinstein L. S. and Shenker A. (1993) J. Clin. Invest. 92, 1119-1125.