Bone alkaline phosphatase and collagen markers as early predictors of height velocity response to growth-promoting treatments in short normal children

Clinical Endocrinology

Volumn 44, Issue 4, 1996, Pages 385-394

  Crofton, P M ^a   Stirling, H F ^b   Schonau E ^c   Kelnar, C J H ^b  

^a ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN; HUMAN GROWTH HORMONE; OXANDROLONE; PLACEBO; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; TESTOSTERONE;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GROWTH RATE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SHORT STATURE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029988031     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1996.706cn527.x     Document Type: Article

References (30)

1. Butler, G.E., McKie, M. & Ratcliffe, S.G. (1990). The cyclical nature of prepubertal growth. Annals of Human Biology, 17, 177-198.
2. Crofton, P.M. (1992) Wheat-germ lectin affinity electrophoresis for alkaline phosphatase isoforms in children: age-dependent reference ranges and changes in liver and bone disease. Clinical Chemistry, 38, 663-670.
3. Crofton, P.M., Stirling, H.F. & Kelnar, C.J.H. (1995) Bone alkaline phosphatase and height velocity in short normal children undergoing growth-promoting treatments: a longitudinal study. Clinical Chemistry, 41, 672-678.
4. Danne, T., Grüters, A., Schuppan, D., Quantas, N., Enders, I. & Weber, B. (1989) Relationship of procollagen type III propeptide-related antigens in serum to somatic growth in healthy children and patients with growth disorders. Journal of Pediatrics, 114, 257-260.
5. Deftos, L.J., Wolfert, R.L., Hill, C.S. & Burton, D.W. (1992) Two-site assays of bone gla protein (osteocalcin) deomonstrate immunochemical heterogeneity of the intact molecule. Clinical Chemistry, 38, 2318-2321.
6. Durham, B.H., Robinson, J. & Fraser, W.D. (1995) Differences in the stability of intact osteocalcin in serum, lithium heparin plasma and EDTA plasma. Annals of Clinical Biochemistry, 32, 422-423.
7. Hermanussen, M., Geiger-Benoit, K., Burmeister, J. & Sippell, W.G. (1988) Periodical changes of short term growth velocity ('mini growth spurts') in human growth. Annals of Human Biology, 15, 103-109.
8. Johansen, J.S., Jensen, S.B., Riis, B.J., Rasmussen, L., Zachmann, M. & Christiansen, C. (1990) Seum bone Gla protein: a potential marker of growth hormone (GH) deficiency and the response to GH therapy. Journal of Clinical Endocrinology and Metabolism, 71, 122-126.
9. Kanzaki, S., Hosoda, K., Moriwake, T. (1992). Serum propeptide and intact molecular osteocalcin in normal children and children with growth hormone (GH) deficiency: a potential marker of bone growth and response to GH therapy. Journal of Clinical Endocrinology and Metabolism, 75, 1104-1109.
10. Lampl, M., Veldhuis, J.D. & Johnson, M.L. (1992). Saltation and stasis: a model of human growth. Science, 258, 801-803.
11. Masters, P.W., Jones, R.G., Purves, D.A., Cooper, E.H. & Cooney, J.M. (1994) Commercial assays for serum osteocalcin give clinically discordant results. Clinical Chemistry, 40, 358-363.
12. Neyzi, O., Bundak, R., Molzan, J., Günöz, H., Darendeliler, F. & Saka, N. (1993) Estimation of annual height velocity based on short- versus long-term measurements. Acta Paediatrica, 82, 239-244.
13. Ohlsson, C., Isgaard, J., Törnell, T., Nilsson, A., Isaksson O.G.P. & Lindahl, A. (1993) Endocrine regulation of longitudinal bone growth. Acta Paediatrica Scandinavica, 82 (Suppl. 391), 33-40.
14. Power, M.J. & Fottrell, P.F. (1991) Osteocalcin: diagnostic methods and clinical applications. Critical Reviews in Clinical Laboratory Science, 28, 287-335.
15. Risteli, L. & Risteli, J. (1993) Biochemical markers of bone metabolism. Annals of Medicine, 25, 385-393.
16. Rosalki S.B. & Foo A.Y. (1984) Two new methods for separating and quantifying bone and liver alkaline phosphatase isoenzymes in plasma. Clinical Chemistry, 30, 1182-1186.
17. Rudolf, M.C.J., Zadik, Z., Linn, S. & Hochberg, Z. (1991) Seasonal variation in growth during growth hormone therapy. American Journal of Diseases in Children, 145, 769-772.
18. Saggese, G., Baroncelli, G.I., Bertelloni, S., Cinquanta, L. & Di Nero, G. (1993) Effects of long-term treatment with growth hormone on bone and mineral metabolism in children with growth hormone deficiency. Journal of Pediatrics, 122, 37-45.
19. Saggese, G., Bertelloni, S., Baroncelli, G.I. & Di Nero, G. (1992) Serum levels of carboxyterminal propeptide of type I procollagen in healthy children from 1st year of life to adulthood and in metabolic bone diseases. European Journal of Pediatrics, 151, 764-768.
20. Schiele, F., Henny, J., Hitz, J., Petitclerc, C., Gueguen, R. & Siest, G. (1983) Total bone and liver alkaline phosphatases in plasma: biological variations and reference limits. Clinical Chemistry, 29, 634-641.
21. Shaw, N.J., Dutton, J., Fraser, W.D. & Smith, C.S. (1995) Urinary pyridinoline and deoxypridonoline excretion in children. Clinical Endocrinology, 42, 607-612.
22. Stein, G.S., Lian, J.B. & Owen, T.A. (1990) Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. Journal of the Federation of American Societies for Experimental Biology, 4, 111-123.
23. Tapanainen, P., Risteli, L., Knip, M., Käär, M.-L. & Risteli, J. (1988) Serum aminoterminal propeptide of Type III procollagen: a potential predictor of the response to growth hormone therapy. Journal of Clinical Endocrinology and Metabolism, 67, 1244-1249.
24. The Committee on Enzymes of the Scandinavian Society for Clinical Chemistry and Clinical Physiology. (1974) Recommended methods for the determination of four enzymes in blood. Scandinavian Journal of Clinical Laboratory Investigation, 33, 291-306.
25. Trivedi, P., Hindmarsh, P., Risteli, J., Risteli, L., Mowat, A.P. & Brook, C.G.D. (1989) Growth velocity, growth hormone therapy, and serum concentrations of the amino-terminal propeptide of type III procollagen. Journal of Pediatrics, 114, 225-230.
26. Trivedi, P., Risteli, J., Risteli, L., Hindmarsh, P.C., Brook, C.G. & Mowat, A.P. (1991) Serum concentrations of the Type I and III procollagen propeptides as biochemical markers of growth velocity in healthy infants and children and in children with growth disorders. Pediatric Research, 30, 276-280.
27. Van Hoof, V.O., Hoylaerts, M.F., Geryl, H., Van Mullem, M., Lepoutre, L.G. & De Broe, M.E. (1990) Age and sex distribution of alkaline phosphatase isoenzymes by agarose electrophoresis. Clinical Chemistry, 36, 875-878.
28. Voss, L.D. & Bailey, B.J.R. (1994) Equipping the community to measure children's height: the reliability of portable instruments. Archives of Disease in Childhood, 70, 469-471.
29. Wales, J.K.H. & Gibson, A.T. (1994) Short term growth: rhythms, chaos, or noise? Archives of Disease in Childhood, 71, 84-89.
30. Widhalm, K. & Hölzl, M. (1985) Changes of alkaline phosphatase, inorganic phosphorus and total calcium in sera of 11 to 17 year old healthy adolescents, and their relationship to growth. Journal of Clinical Chemistry and Clinical Biochemistry, 23, 711-717.