Detection of DNA adducts in the white blood cells of B6C3F1 mice treated with benzene

Carcinogenesis

Volumn 17, Issue 1, 1996, Pages 151-153

  Lévay, György ^a,b   Pathak, Deena N ^a   Bodell, William J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Budapest's Postgraduate Medical University   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; NUCLEOTIDE; PHOSPHORUS 32;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CONTROLLED STUDY; DNA ADDUCT; DOSE RESPONSE; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BENZENE; BONE MARROW; DNA ADDUCTS; LEUKOCYTES; MICE; OCCUPATIONAL EXPOSURE;

EID: 0029987901     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.1.151     Document Type: Article

References (34)

1. Paustenbach,D.F., Bass,R.D. and Price,P. (1993) Benzene toxicity and risk assessment, 1972-1992. Implications for future regulation. Environ. Health Perspect., 101, 177-200.
2. Wallace,L.A. (1989) Major sources of benzene exposure. Environ. Health Perspect., 82, 165-169.
3. IARC (1986) Tobacco Smoking, vol. 38. International Agency for Research on Cancer, Lyon.
4. Goldstein,B.D. (1977) Hematoxicity in humans. J. Toxicol. Environ. Health, 2, 69-105.
5. Rinsky,R.A., Smith,A.B., Hornung,R., Filloon,T.G., Young,R.J., Okun,A.H. and Landrigan,P.J. (1987) Benzene and leukemia. An epidemiologic risk assessment. New. Engl. J. Med., 316, 1044-1050.
6. Snyder,C.A., Goldstein,B.D., Sellakumar,A., Wolman,S.R., Bromberg,I., Erlichman,M.N. and Laskin,S. (1978) Hematoxicity of inhaled benzene to Sprague-Dawley rats and AKR mice at 300 p.p.m. J. Toxicol Environ. Health, 4, 605-618.
7. Green,J.D., Snyder,C.A., LoBue,J., Goldstein,B.D. and Albert,R.E. (1981) Acute and chronic dose/response effect of benzene inhalation on the peripheral blood, bone marrow and spleen cells of CD-I male mice. Toxicol. Appl. Pharmacot., 59, 204-214.
8. Tunek,A., Hogstedt,B. and Olofsson,T. (1982) Mechanism of benzene toxicity, effects of benzene and benzene metabolites on bone marrow cellularity, number of granulopoietic stem cells and frequency of micronuclei in mice. Chem. -Biol. Interactions, 39, 129-138.
9. Tice,R.R., Luke,C.A. and Drew,R.T. (1989) Effect of exposure route and duration on benzene-induced genotoxic and cytotoxic bone marrow damage in mice, Environ, Health Perspect., 82, 65-74.
10. Maltoni,C., Ciliberti,A., Cotti,G., Conti,B. and Belpoggi,F. (1989) Benzene: an experimental multipotential carcinogen. Results of the long-term bioassays performed at the Bologna Institute of Oncology. Environ. Health Perspect., 82, 102-124.
11. Huff,J.E., Haseman,J.K., DeMarini,D.M., Eustis,S., Maronpot,R.R., Peters, A.C., Persing,R.L., Chrisp,C.E. and Jacobs,A.C. (1989) Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice. Environ. Health Perspect., 82, 125-163.
12. Kalf,G.F. (1987) Recent advances in the metabolism and toxicity of benzene. Crit. Rev. Toxicol., 18, 141-159.
13. Guengerich,F.P., Kim,D.H. and Iwasaki,M. (1991) Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol., 4, 168-179.
14. Sabourin,P.J., Bechtold,W.E., Birnbaum,L.S., Lucier,G.W. and Henderson,R.F. (1989) Effect of exposure concentration, exposure rate and route of administration on metabolism of benzene by Fischer 344 rats and B6C3F1 mice. Toxicol. Appl. Pharmacol. 99, 421-444.
15. Schlosser,P.M., Bond,J.A. and Medinsky,M.A. (1993) Benzene and phenol metabolism by mouse and rat liver microsomes. Carcinogenesis, 14, 2477-2486.
16. Rickert,D.E., Edgar,T.S., Barrow,C.S., Bus,J. and Irons,R.D. (1979) Benzene absorption in rats after inhalation exposure. Toxicol. Appl. Pharmacol., 49, 417-423.
17. Greenlee,W.F., Gross,E.A. and Irons,R.D. (1981) Relationship between benzene toxicity and the disposition of 14C-labeled benzene metabolites in the rat. Chem. -Biol Interactions, 33, 285-299.
18. Subrahmanyam,V.V., Kolachana,P. and Smith,M.T. (1991) Metabolism of hydroquinone by human myeloperoxidase: mechanisms of stimulation by other phenolic compounds. Arch. Biochem. Biophys., 286, 76-84.
19. Sadler,A., Subrahmanyam,V.V. and Ross,D. (1988) Oxidation of catechol by horseradish peroxidase and human leukocyte peroxidase: reactions of o-benzoquinone and o-benzosemiquinone. Toxicol. Appl. Pharmacol., 93, 62-71.
20. Schlosser,M.J., Shurina,R.D. and Kalf,G.F. (1990) Prostaglandin H synthase catalyzed oxidation of hydroquinone to a sulfhydryl-binding and DNA damaging metabolite. Chem. Res. Toxicol., 3, 333-339.
21. 32P-postlabeling. Carcinogenesis, 12, 1181-1186.
22. Lévay,G. and Bodell,W.J. (1992) Potentiation of DNA adduct formation in HL-60 cells by combination of benzene metabolites. Proc. Natl Acad. Sci. USA, 89, 7105-7109.
23. Lévay,G., Ross,D. and Bodell,W.J. (1993) Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells, mouse bone marrow macrophages and human bone marrow. Carcinogenesis, 14, 2329-2334.
24. 32P-postlabeling methods for DNA adduct detection: Overview and critical evaluation. Drug Metab. Rev., 26, 67-55.
25. 32P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis, 7, 1543-1551.
26. Ross,J., Nelson,G., Kligerman,A., Erexson,G., Bryant,M., Early,K., Gupta, R. and Nesnow,S. (1990) Formation and persistence of novel benzo[a]pyrene adducts in rat lung, liver and peripheral blood lymphocyte DNA. Cancer Res., 50, 5088-5094.
27. Levy,G.N. (1993) DNA-carcinogen adducts in circulating leukocytes as indicators of arylamine carcinogen exposure. Fund. Appl. Toxicol., 21, 23-30.
28. Reddy,V.J. and Randerath,K. (1990) A comparison of DNA adduct formation in white blood cells and internal organs of mice exposed to benzo[a]pyrene, dibenzo[c,G]carbazole, safrole and cigarette smoke condensate. Mutat. Res., 241, 37-48.
29. Schut,H.A.J. and Herzog,C.R. (1992) Formation of DNA adducts of 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) in male Fischer344 rats. Cancer Lert., 67, 117-124.
30. Pathak,D.N., Lévay,G. and Bodell,W.J. (1995) DNA adduct formation in the bone marrow of B6C3F1 mice treated with benzene. Carcinogenesis, 16, 1803-1808.
31. Walker,V.E., Fennel,T.R., Boucheron,J.A., Fedtke,N., Ciroussel,F. and Swenberg,J.A. (1990) Macromolecular adducts of ethylene oxide: a literature review and a time-course study on the formation of 7-(2-hydroxyethyl)guanine following exposures of rats by inhalation. Mutat. Res., 233, 151-164.
32. 32P-analysis of DNA adducts in tissues of benzene treated rats. Environ. Health Perspect., 82, 253-257.
33. Reddy,M.V., Schultz,S.C., Blackburn,G.R. and Mackerer,C.R. (1994) Lack of DNA-adduct formation in mice treated with benzene. Mutat Res., 325, 149-155.
34. Rothman,N., Haas,R., Hayes,R.B., et al. (1995) Benzene induces geneduplicating but not gene-inactivating mutations at the glycophorin A locus in exposed humans. Proc. Natl Acad. Sci. USA, 92, 4069-1073.