Effect of celiprolol therapy on arterial dilatation in experimental hypertension

British Journal of Pharmacology

Volumn 119, Issue 6, 1996, Pages 1137-1144

  Tolvanen, Jari Petteri ^a   Wu, Xiumin ^a   Kähönen, Mika ^b   Sallinen, Kirsimarja ^a   Mäkynen, Heikki ^a   Pekki, Anu ^a   Pörsti, Ilkka ^b  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Arterial smooth muscle; Blood pressure; Celiprolol; Endothelium; Spontaneously hypertensive rat

Indexed keywords

ACETYLCHOLINE; ARGININE METHYL ESTER; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CELIPROLOL; DICLOFENAC; ISOPRENALINE; NITROPRUSSIDE SODIUM; NORADRENALIN; POTASSIUM CHLORIDE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DILATATION; ARTERY MUSCLE; ARTERY RESISTANCE; ARTERY TONE; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DOSE RESPONSE; HYPERPOLARIZATION; HYPERTENSION; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE RELAXATION; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR ENDOTHELIUM;

EID: 0029987550     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb16015.x     Document Type: Article

References (39)

1. +]: A functional approach to separating EDHF- and EDNO-related mechanisms in perfused rat mesenteric arterial bed. J. Cardiovasc. Pharmacol., 21, 423-429.
2. ARVOLA, P., RUSKOAHO, H., WUORELA, H., PEKKI, A., VAPAATALO, H. & PÖRSTI, I. (1993). Quinapril treatment and arterial smooth muscle responses in spontaneously hypertensive rats. Br. J. Pharmacol., 108, 980-990.
3. BOLOTINA, V.M., NAJIBI, S., PALACINO, J.J., PAGANO, P.J. & COHEN, R.A. (1994). Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature, 368, 850-853.
4. +-channels opened by cromakalim, acetylcholine and substance P in rat aorta and porcine coronary artery. Br. J. Pharmacol., 102, 585-594.
5. BÜLBRING, E. & TOMITA, T. (1987). Catecholamine action on smooth muscle. Pharmacol. Rev., 39, 49-96.
6. CHATELAIN, P., WAELBROECK, M., CAMUS, J.-C., DE NEEF, P., ROBBERECHT, P., ROBA, J. & CHRISTOPHE, J. (1981). Comparative effects of α-methyldopa, propranolol and hydralazine therapy on caridac adenylate cyclase activity in normal and spontaneously hypertensive rats. Eur. J. Pharmacol., 72, 17-25.
7. CHEN, G., SUZUKI, H. & WESTON, A.H. (1988). Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br. J. Pharmacol., 95, 1165-1174.
8. CLOZEL, M., KUHN, H. & HEFTI, F. (1990). Effects of angiotensin converting enzyme inhibitors and of hydralazine on endothelial function in hypertensive rats. Hypertension, 16, 532-540.
9. DZAU, V.J., GIBBONS, G.H. & PRATT, R.E. (1991). Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia. Hypertension, 18 (suppl. II), II-100-II-105.
10. FELOTOU, M. & VANHOUTTE, P.M. (1988). Endothelium-dependent hyperpolarization of canine coronary smooth muscle. Br. J. Pharmacol., 93, 515-524.
11. FUJII, K., OHMORI, S., TOMINAGA, M., ABE, I., TAKATA, Y., OHYA, Y., KOBAYASHI, K. & FUJISHIMA, M. (1993). Age related changes in endothelium-dependent hyperpolarization in the rat mesenteric artery. Am. J. Physiol., 265, H509-H516.
12. FUJII, K., TOMINAGA, M., OHMORI, S., KOBAYASHI K., KOGA, T., TAKATA, Y. & FUJISHIMA, M. (1992). Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats. Cir. Res., 70, 660-669.
13. GARLAND, C.J. & MCPHERSON, G.A. (1992). Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in rat small mesenteric artery. Br. J. Pharmacol., 105, 429-435.
14. GRAVES, J. & POSTON, L. (1993). β-Adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: a role for the endothelium and nitric oxide. Br. J. Pharmacol., 108, 631-637.
15. GRAY, D.W. & MARSHALL, I. (1992). Novel signal transduction pathway mediating endothelium-dependent β-adrenoceptor vasorelaxation in rat thoracic aorta. Br. J. Pharmacol., 107, 684-690.
16. HIRAWA, N., UEHURA, Y., NUMABE, A., TAKADA, S., MATSUOKA, H., IKEDA, T., SUGIMOTO, T., YAGI, S. & ISHII, M. (1991). Stimulating effects of atenolol on vasodepressor prostaglandin generation in spontaneously hypertensive rats. Clin. Sci., 81, 499-507.
17. JANCZEWSKI, P., BOULANGER, C., IQBAL, A. & VANHOUTTE, P.M. (1987). Endothelium-dependent effects of carteolol. J. Pharmacol. Exp. Ther., 247, 590-595.
18. KÄHÖNEN, M., MÄKYNEN, H., ARVOLA, P. & PÖRSTI, I. (1994). Enhancement of arterial relaxation by long-term atenolol treatment in spontaneously hypertensive rats. Br. J. Pharmacol., 112, 925-933.
19. KÄHÖNEN, M., MÄKYNEN, H., ARVOLA, P., WUORELA, H. & PÖRSTI, I. (1995a). Arterial function after trichlormethiazide therapy in spontaneously hypertensive rats. J. Pharmacol. Exp. Ther., 272, 1223-1230.
20. KÄHÖNEN, M., MÄKYNEN, H., WU, X., ARVOLA, P & PÖRSTI, I. (1995b). Endothelial function in spontaneously hypertensive rats: influence of quinapril treatment. Br. J. Pharmacol., 115, 859-867.
21. 1-adrenoceptor blockade with atenolol. J. Cardiovasc. Pharmacol., 7, 232-237.
22. LI, J., BIAN, K. & BUKOSKI, R.D. (1994). A non-cyclo-oxygense, non-nitric oxide relaxing factor is present in resistance arteries of normotensive but not spontaneously hypertensive rats. Am. J. Med. Sci., 307, 7-14.
23. LUND-JOHANSEN, P. (1979). Hemodynamic consequences of long-term beta-blocker therapy: A 5-year follow-up study of atenolol. J. Cardiovasc. Pharmacol., 1, 487-495.
24. LYSBO SVENDSEN, T., HARTLING, O. & TRAP-JENSEN, J. (1979). Immediate haemodynamic effects of propranolol, practolol, pindolol, atenolol and ICI 89,406 in healthy volunteers. Eur. J. Clin. Pharmacol., 15, 223-228.
25. MÄKYNEN, H., KÄHÖNEN, M., ARVOLA, P., WU, X., WUORELA, H. & PORSTI, I. (1996a). Endothelial function in deoxycorticosterone-NaCl hypertension: effect of calcium supplementation. Circulation, 93, 1000-1008.
26. MÄKYNEN, H., KÄHÖNEN, M., WU, X., WUORELA, H. & PÖRSTI, I. (1996b). Reversal of hypertension and endothelial dysfunction in deoxycorticosterone-NaCl treated rats by high calcium diet. Am. J. Physiol., 270, (in press).
27. MAN IN'T VELD, A.J. (1991). Vasodilatation, not cardiodepression, underlies the antihypertensive effect of beta-adrenoceptor antagonists. Am. J. Cardiol., 67, 13B-17B.
28. MAN IN'T VELD, A.J., MEIRACKER, A. & SCHALEKAMP, M.A.D.H. (1986). The effect of β blockers on total peripheral resistance. J. Cardiovasc. Pharmacol., 8, (suppl. 4), S49-S60.
29. + channel opened by cromakalim. Br. J. Pharmacol., 103, 1184-1190.
30. MEHTA, J.L., LOPEZ, L.M., CHEN, L. & COX, O.E. (1994). Alterations in nitric oxide synthase activity, superoxide anion generation, and platelet aggregation in systemic hypertension, and effects of celiprolol. Am. J. Cardiol., 74, 901-905.
31. MEIRACKER, A.H., MAN IN'T VELD, A.J., BOOMSMA, F., FISCHBERG, D.J., MOLINOFF, P.B. & SCHALEKAMP, M.A.D.H. (1989). Hemodynamic and β-adrenergic receptor adaptions during long-term β-adrenoceptor blockade; Studies with acebutolol, atenolol, pindolol, and propranolol in hypertensive patients. Circulation, 80, 903-914.
32. MEIRACKER, A.H., MAN IN'T VELD, A.J., RITSEMA VAN ECK, H.J., BOOMSMA, F., SCHALEKAMP, M.A.D.H. (1988). Hemodynamic and hormonal adaptations to β-adrenoceptor blockade; A 24-hour study of acebutolol, atenolol, pindolol, and propranolol in hypertensive patients. Circulation, 78, 957-968.
33. MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide; physiology, pathophysiology, and pharmacology. Pharmacol. Rev., 43, 109-142.
34. OHLSTEIN, E.H., VICKERY, L., ARLETH, A., BARONE, F., SUNG, C.P., CAMDEN, A., MCCARTNEYM L. (1994). Carvedilol, a novel cardiovascular agent, inhibits development of vascular and ventricular hypertrophy in spontaneously hypertensive rats. Clin. Exp. Hypertens., 16, 163-177.
35. STEINBERG, S.F., JAFFE, E.A. & BILEZIKIAN, J.P. (1984). Endothelial cells contain beta adrenoceptors. Naunyn-Schmiedeberg's Arch. Pharmacol., 325, 310-313.
36. TREASURE, C.B., MANOUKIAN, S.V., KLEIN, J.L., VITA, J.A., NABEL, E.G., RENWICK, G.H., SELWYN, A.P., ALEXANDER, R.W. & GANZ, P. (1992). Epicardial coronary artery responses to acetylcholine are impaired in hypertensive patients. Circ. Res., 71, 776-781.
37. VANHEEL, B., VANDERVOORDE, J. & LEUSEN, I. (1994). Contribution of nitric oxide to the endothelium-dependent hyperpolarization in rat aorta. J. Physiol., 475, 277-284.
38. WALDRON, G.J. & GARLAND, C.J. (1994). Effect of potassium channel blockers on L-NAME insensitive relaxation in rat small mesenteric artery. Can. J. Physiol. Pharmacol., 72 (Suppl. 1), 115.
39. WATT, P.A.C. & THURSTON, H. (1989). Endothelium-dependent relaxation in resistance vessels from the spontaneously hypertensive rats. J. Hypertens., 7, 661-666.