Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis

European Journal of Gastroenterology and Hepatology

Volumn 8, Issue 7, 1996, Pages 699-703

  Delhaye, Myriam ^a   Meuris, Sylvain ^a   Gohimont, Anne Catherine ^a   Buedts, Karine ^a   Cremer, Michel ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

Chronic pancreatitis; Exocrine pancreatic insufficiency; Pancreatic enzyme

Indexed keywords

KREON; OMEPRAZOLE; PANCREAS ENZYME; PANCREAS EXTRACT; PANCRELIPASE;

ADULT; AGED; ARTICLE; CHRONIC PANCREATITIS; CLINICAL ARTICLE; CLINICAL TRIAL; DIABETES MELLITUS; DRUG COMBINATION; DRUG COMPARISON; DRUG EFFICACY; DRUG SAFETY; DRUG THERAPY; ENTERIC COATED TABLET; ENZYME THERAPY; FECES; FECES ANALYSIS; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PHARMACEUTICS; PHARMACOLOGY; PRIORITY JOURNAL; PROSPECTIVE STUDY; STEATORRHEA; SUBSTITUTION THERAPY;

CROSS-OVER STUDIES; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; EXOCRINE PANCREATIC INSUFFICIENCY; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; LIPASE; MALE; MIDDLE AGED; OMEPRAZOLE; PANCREATIC EXTRACTS; PANCREATIN; PANCREATITIS; PANCREATITIS, ALCOHOLIC; PANCRELIPASE; PROSPECTIVE STUDIES;

EID: 0029987249     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Di Magno EP, Layer P, Clain JE: Chronic pancreatitis. In The Pancreas: Biology, Pathobiology and Disease, 2nd edition. Edited by Go VLW, Di Magno EP, Gardner JD, Lebenthal E, Reber HA, Scheele GA. New York: Raven; 1993:665-706.
2. Lankisch PG: Enzyme treatment of exocrine pancreatic insufficiency in chronic pancreatitis. Digestion 1993, 54:21-29.
3. Roberts IM: Enzyme therapy for malabsorption in exocrine pancreatic insufficiency. Pancreas 1989, 4:496-503.
4. Dutta SK, Rubin J, Harvey J: Comparative evaluation of the therapeutic efficacy of a pH-sensitive enteric coated pancreatic enzyme preparation with conventional pancreatic enzyme therapy in the treatment of exocrine pancreatic insufficiency. Gastroenterology 1983, 84:476-482.
5. Dobrilla G: Management of chronic pancreatitis. Focus on enzyme replacement therapy. Int J Pancreatol 1989, 5:17-29.
6. De Young JL: Development of pancreatic enzyme microsphere technology and US findings with Pancrease in the treatment of chronic pancreatitis. Int Pancreatol 1989, 5:31-36.
7. Morrison G, Morrisson JM, Redmond AOB, Byers CA, McCracken KJ, Dodge JA, et al.: Comparison between a standard pancreatic supplement and a high enzyme preparation in cystic fibrosis. Aliment Pharmacol Ther 1992, 6:549-555.
8. Dutta SK, Russell RM, Iber FL: Influence of exocrine pancreatic insufficiency on the intraluminal pH of the proximal small intestine. Dig Dis Sci 1979, 24:529-534.
9. Andrén-Sandberg Å: Theory and practice in the individualization of oral pancreatic enzyme administration for chronic pancreatitis. Int J Pancreatol 1989, 5:51-62.
10. Ceria School of Dietetics: The composition of Foods. Edited by Belgian Society of Biotechnology and Food Industry, 1986.
11. Van Havere IR, Muls E: The Composition of Foods. Edited by Nubel. Brussels: Nubel; 1992.
12. Van de Kamer JH, Ten Bokkel Huinink H, Weyers HA: Rapid method for the determination of fat in faeces. J Biol Chem 1949, 177:347-355.
13. Grant GH, Kachmar JF: The proteins of body fluids. In Fundamentals of Clinical Chemistry, 2nd edition. Edited by Tietz N. Philadelphia: WB Saunders, 1976:298-376.
14. Smyth RL, Van Velzen D, Smyth AR, Lloyd DA, Heaf DP: Strictures of ascending colon in cystic fibrosis and high-strength pancreatic enzymes. Lancet 1994, 343:85-86.
15. Atkinson SN: A comparative study of the enzyme activity, acid resistance and dissolution characteristics of four enteric coated microsphere preparations of pancreatin. Eur J Clin Res 1991, 1:37-45.
16. Meyer JH, Elashoff J, Porter-Fink V, Dressman J, Amidon GL: Human postprandial gastric emptying of 1-3-millimeter spheres. Gastroenterology 1988, 94:1315-1325.
17. Thiruvengadam R, Di Magno E: Inactivation of human lipase by proteases. Am J Physiol 1988, 255:G476-G481.
18. Malesci A, Mariani A, Mezzi G, Bocchia P, Basilico M: New enteric-coated high-lipase pancreatic extract in the treatment of pancreatic steatorrhea. J Clin Gastroenterol 1994, 18:32-35.
19. Robinson PJ, Olinsky A, Smith AL, Chitravanshi SB: High compared with standard dose lipase pancreatic supplement. Arch Dis Child 1989, 64:143-145.
20. Pettei MJ, Leonidas JC, Levine JJ, Gorvoy JD: Pancolonic disease in cystic fibrosis and high-dose pancreatic enzyme therapy. J Pediatr 1994, 125:587-589.
21. Taylor CJ: The problems with high dose pancreatic enzyme preparations. Drug Safety 1994, 11:75-79.
22. Jones R, Franklin K, Spicer R, Berry J: Colonic strictures in children with cystic fibrosis on low-strength pancreatic enzymes. Lancet 1995, 346:499-500.
23. Heijerman HG, Lamers CB, Bakker W: Omeprazole enhances the efficacy of pancreatin (Pancrease) in cystic fibrosis. Ann Intern Med 1991, 114:200-201.
24. Doty JE, Fink AS, Meyer JH: Alterations in digestive function caused by pancreatic disease. Surg Clin North Am 1989, 69:447-465.
25. Raimondo M, Di Magno EP: Lipolytic activity of bacterial lipase survives better than that of porcine lipase in human gastric and duodenal content. Gastroenterology 1994, 107:231-235.