Microsequencing of organic anion-binding proteins from basolateral plasma membranes in hepatocytes after photoaffinity labelling with bumetanide and 7,7-azotaurocholate

Cellular Physiology and Biochemistry

Volumn 6, Issue 1-2, 1996, Pages 13-27

  Brühla, Brigitta ^a   Tripierb, Didier ^b   Jouvenalb, Karin ^b   Guckesb, Sonja ^b   Kolaca, Mäzen Ottallah ^a   Petzingera, Ernst ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b SANOFI   (France)

Author keywords

Bile acids; Cytokeratin 8; Loop diuretics; Organic anion transport; Protein disulfide isomerase; Two dimensional gel electrophoresis

Indexed keywords

BILE ACID; BINDING PROTEIN; BUMETANIDE; CYTOKERATIN; LOOP DIURETIC AGENT; PROTEIN DISULFIDE ISOMERASE; TAUROCHOLIC ACID;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; BASOLATERAL MEMBRANE; ENZYME INHIBITION; GEL ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER PARENCHYMA; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN ISOLATION; RAT; SEQUENCE HOMOLOGY;

EID: 0029987221     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000154791     Document Type: Article

References (51)

1. Petzinger E: Transport of organic anions in the liver. An update on bile acid, fatty acid, monocarbox-ylate, anionic amino acid, chole-philic organic anion, and anionic drug transport. Rev Physiol Bio-chem Pharmacol 1994; 123:49—211.
2. Oude Elferink RPJ, Meijer DKF, Kuipers F, Jansen PLM, Groen AK, Groothuis GMM: Hepatobiliary secretion of organic compounds; molecular mechanism of membrane transport. Biochim Biophys Acta 1995;1241:215-268.
3. Möller JV, Sheikh MI: Renal organic anion transport system: Pharmacological, physiological, and biochemical aspects. Pharmacol Rev 1983;34:315-358.
4. Ullrich KJ, Rumrich G, Klöss S: Contraluminal para-aminohippu-rate transport in the proximal tubule of rat kidney. IV. Specificity: mono-and polysubstitutcd benzene analogs. Pflügers Arch 1988:413:134-146.
5. Ullrich KJ, Rumrich G, Fritsch G, Klöss S: Contraluminal para-amino-hippurate transport in the proximal tubule of rat kidney. III. Specificity: monocarboxylic acids. Pflügers Arch 1987;409:547-554.
6. Petzinger E, Föllmann W, Blumrich M, Schermuly R, Schulz S, Hahnen J, Feit PW: Interaction of bumetan-ide derivatives with hepatocellular bile acid uptake. Am J Physiol 1993; 265:G942-G954.
7. Hagenbuch B, Stieger B. Foguet M, Lübbcrt H, Meier PJ: Functional expression cloning and characterization of the hepatocyte NaVbile acid cotransport system. Proc Natl Acad Sei USA 1991;88:10629-10633.
8. Jacquemin E, Hagenbuch B, Stieger B, Wolkoff AW, Meier PJ: Expression cloning of a rat liver NV-inde-pendent organic anion transporter. Proc Natl Acad Sei USA 1994;91: 133-137.
9. Horz JA, Honscha W, Petzinger E: Bumetanide is not transported by the Ntcp or by the Oatp: Evidence for a third organic anion transporter in rat liver cells. Biochim Biophys Acta 1996; 1300:114-118.
10. Kurz G, Müller M, Schramm U, Ge-rok W: Identification and function of bile salt binding polypeptides of hepatocyte membrane; in Petzinger E, Kinne RKH, Sies H (eds): Hepatic Transport of Organic Substances. Berlin, Springer, 1989, pp 267-285.
11. Petzinger E, Honscha W, Schenk A, Follmann W, Deutscher J, Zierold K, Kinne RKH: Photoaffinity labeling of plasma membrane proteins involved in the transport of loop diuretics into hépatocytes. Eur J Pharmacol 1991;208:53-65.
12. Honscha W. Ottallah M, Schenk A, Schuh K, Petzinger E: Separation and purification by two-dimensional gel electrophoresis of a 52-54 kD bumetanide binding protein from rat liver plasma membranes. Eur J Pharmacol 1992;226:215-223.
13. Hoffmann A, Müllner S, Ziegler K, Fasold H: Purification and partial sequence of proteins involved in the cholic acid transport into rat liver hépatocytes. J Prot Client 1993; 12: 765-769.
14. Ottallah-Kolac M, Tripier D, Brühl B, Platte HD, Jouvenal K. Schuh K, Petzinger E: The 60 kD bumetanide binding protein from rat liver is a catalase. Eur J Biochem 1995;228: 506-514.
15. Blitzer BL, Donovan CB: A new method for the rapid isolation of ba-solateral plasma membrane vesicles from rat liver. J Biol Chem 1984; 259:9295-9301.
16. Schoner W, von Ilberg C, Kramer R, Seubert W: On the mechanisms of Na*- and K'-stimulated hydrolysis of adenosine triphosphate. Eur J Biochem 1967;1:334-343.
17. 2*- and Na*-K*-ATPasc activity. J Lab Clin Med 1979;93:790-799.
18. Nordlic RC, Lygre DG: The inhibition by citrate of inorganic pyrophosphate-glucose-phosphotransferase and glucose-6-phosphatase. J Biol Chem 1966;241:3136-3141.
19. Frimmer M, Ziegler K: Photoaffini-ty labeling of whole cells by flashing light: A simple apparatus for high-energy ultraviolet flashes. Biochim Biophys Acta 1986;855:143-146.
20. O’Farrell PH: High-resolution two-dimensional electrophoresis of proteins. J Biol Chem 1975;250:4007-4021.
21. Laemmli U K: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
22. Rosenfeld J, Capdevielle J, Guillemot JC, Ferrara P: In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis. Anal Biochem 1992;203:173-179.
23. Ball EH: Quantitation of proteins by elution of Coomassie Brilliant Blue R from stained bands after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem 1986;155:23-27.
24. Hawkes R, Niday E, Gordon J: A dot-immunobinding assay for monoclonal and other antibodies. Anal Biochem 1982; 119:142-147.
25. Honscha W, Ottallah M, Kistner A, Platte HD, Petzinger E: A membrane-bound form of protein disulfide isomerase and the hepatic uptake of organic anions. Biochim Biophys Acta 1993; 1153:175—183.
26. Auberger P, Falquerho L, Contreres JO, Pages G, Le Cam G, Rossi B, Le Cam A: Characterization of a natural inhibitor of the insulin receptor tyrosine kinase: cDNA cloning, purification, and anti-mitogenic activity. Cell 1989;58:631-640.
27. Morita T, Tondella ML, Takemoto Y, Hashido K, Ichinose Y, Nazaki M, Matsushiro A: Nucleotide sequence of mouse EndoA cytokeratin cDNA reveals polypeptide characteristics of the type-II keratin subfamily. Gene 1988;68:109-117.
28. Edman JC, Ellis L, Blacher RW, Roth RA, Rutter WJ: Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin. Nature 1985;317:267- 270.
29. Bennett CF, Balcarek JM, Varrichio A, Crooke ST: Molecular cloning and complete amino-acid sequence of form-I phosphoinositide-specific phospholipase C. Nature 1988;334: 268-270.
30. Urade R, Nasu M, Moriyama T, Wada K, Kito M: Protein degradation by the phosphoinositide-specific phospholipase C-a family from rat liver endoplasmic reticulum. J Biol Chem 1992;267:15152-15159.
31. Ohtake A, Takiguchi M, Shigeto Y, Amaya Y, Kawamoto S, Mori M: Structural organization of the gene for rat liver-type arginase. J Biol Chem 1988:5:2245-2249.
32. Bertrams AA, Ziegler K: New substrates of the multispecific bile acid transporter in liver cells: Interference of some linear renin inhibiting peptides with transport proteins for bile acids. Biochim Biophys Acta 1991;1073:213-220.
33. Bertrams AA, Ziegler K: Hepatocellular uptake of peptides by bile acid transporters. Biochim Biophys Acta 1991;1091:337-348.
34. Horiuchi R, Yamauchi K, Hayashi H, Koya S, Takeuchi Y, Kato K, Kobayashi M, Takikawa H: Purification and characterization of 55 kDa protein with 3,5.3'-triiodo-C-thyronine-binding activity and protein disulfide-isomerase activity from beef liver membrane. Eur J Biochem 1989;183:529-538.
35. Bulleid N, Freedman RB: Defective co-translational formation of disulphide bonds in protein disulphide isomerase-deficient micro-somes. Nature 1988;335:649-651.
36. Freedman RB: Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins. Cell 1989;57:1069-1072.
37. Akagi S, Yamamoto A, Yoshimoro T, Masaki R. Ogawa R, Tashiro Y: Distribution of protein disulfide isomerase in rat hépatocytes J His-tochem Cytochem 1988,36:1533-1542.
38. Maeda K, Tsugita A, Dalzoppo D, Vilbois F, Schurmann P: Further characterization and amino acid sequence of m-type thioredoxins from spinach chloroplasts. Eur J Biochem 1986;154:197-203.
39. Koivu J, Myllylä R, Helaakoski T, Pihlajaniemi T, Tasanen K, Kivirkko KI: A single polypeptide acts both as the ß-subunit of prolyl-4-hydroxylase and as a protein disulfide-isomerase. J Biol Chem 1987; 262:6447-6449.
40. Pihlajaniemi T, Helaakoski T, Tasanen K, Myllylä R, Huhtala ML. Koivu J, Kivirikko KI: Molecular cloning of the ß-subunit and protein disulphide isomerase are products of the same gene. EMBO J 1987;6: 643-649.
41. Geetha-Habib M, Noiva R, Kaplan HA, Lcnnarz WJ: Glycosylation site-binding protein, a component of oligosaccharyl transferase, is highly similar to three other 57 kD luminal proteins of the ER. Cell 1988;54: 1053-1056.
42. French S: Cytoskeleton: Intermediate filaments; in Arias IM, Boyer JL, Fausto N, Jakoby WB, Schächter DA, Shafritz DA (eds): The Liver: Biology and Pathobiology. New York, Raven Press, 1994.
43. Moll R. Franke WW. Schiller DL: The catalog of human cytokeratins: Pattern of expression in normal epi-thelia, tumors and cultured cells. Cell 1982;31:11-24.
44. Hatzfeld M, Franke WW: Pair formation and promiscuity of cytokeratins: Formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides. J Cell Biol 1985; 101:1826-1841.
45. Kramer W, Bickel U, Buscher HP, Gerok W, Kurz G: Bile-salt-binding polypeptides in plasma membranes of hepatocytes revealed by photoaffinity labelling. Eur J Biochem 1982; 129:13-24.
46. Wieland T, Nassal M, Kramer W, Flicker G, Bickel U, Kurz G: Identity of hepatic membrane transport systems for bile salt, phalloidin, and antamanide by photoaffinity labeling. Proc Natl Acad Sei USA 1984; 81:5232-5236.
47. +/KVCl- cotransport system by reorganization of the actin filaments in Ehrlich ascites tumor cells. Biochim Biophys Acta 1992; 1110:199-201.
48. Le Cam A, Magnaldo I, Le Cam G, Auberger P: Secretion of a major phosphorylated glycoprotein by hepatocytes. Characterization of specific antibodies and investigations of the processing, excretion kinetics, and phosphorylation. J Biol Chem 1985;260:15965-15971.
49. Martin JL, Pumford NR, LaRosa AC, Martin BM, Gonzaga HMS, Beaven MA, Pohl LR: A metabolite of halothane covalently binds to an endoplasmic reticulum protein that is highly homologous to phos-phatidylinositol-specific phospholipase C-a but has no activity. Biochem Biophys Res Commun 1991; 178:679-685.
50. Mobbs CV, Fink G, Pfaf TDW: HIP-70: A protein induced by estrogen in the brain and LH-RH in the pituary. Science 1990;247:1477-1479.
51. Ampola MG: The urea cycle: Enzymes and defects; in Arias IM, Boyer JL, Fausto N, Jakoby WB, Schächter DA, Shafritz DA (eds): The Liver: Biology and Pathobiology. New York, Raven Press, 1994.