Relative hepatotoxicity of 2-(substituted phenyl)thiazoles and substituted thiobenzamides in mice: Evidence for the involvement of thiobenzamides as ring cleavage metabolites in the hepatotoxicity of 2-phenylthiazoles

Toxicology Letters

Volumn 85, Issue 2, 1996, Pages 101-105

  Mizutani, Tamio ^a   Suzuki, Kiyomi ^a  

^a KYOTO PREFECTURAL UNIVERSITY   (Japan)

Author keywords

2 (para substituted phenyl)thiazoles; Buthionine sulfoximine; Hepatotoxicity; Methylglyoxal; Parasubstituted thiobenzamides

Indexed keywords

ALANINE AMINOTRANSFERASE; BUTHIONINE SULFOXIMINE; THIAZOLE DERIVATIVE; THIOBENZAMIDE DERIVATIVE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; LIVER TOXICITY; MALE; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; URINARY EXCRETION;

ANIMALIA;

EID: 0029986641     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(96)03646-6     Document Type: Article

References (11)

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