IL-12 administered in vivo to young and aged mice. Discrepancy between the effects on tumor growth in vivo and cytotoxic T lymphocyte generation ex vivo: Dependence on IFN-γ

International Immunology

Volumn 8, Issue 5, 1996, Pages 661-673

  Horvath Arcidiacono, Judith A ^a   Mostowski, Howard S ^a   Bloom, Eda T ^a  

^a Center for Biologics Evaluation/Res   (United States)

Author keywords

Aging; CD4+; CD8+; IL 10; IL 4; Immunotherapy; NK cells; Splenomegaly

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DNA SYNTHESIS; DOSE RESPONSE; EFFECTOR CELL; FEMALE; HELPER CELL; INTRAPERITONEAL DRUG ADMINISTRATION; MACROPHAGE; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SPLENOMEGALY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUMOR GROWTH;

EID: 0029986623     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.5.661     Document Type: Article

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