The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effects on cytotoxicity of cis-diaminedichloroplatinum (II) (CDDP) in human brain tumor cell lines

Anticancer Research

Volumn 16, Issue 1, 1996, Pages 39-48

  Basu, Hirak S ^a   Pellarin, Malgorzata ^c   Feuerstein, Burt G ^c   Marton, Laurence J ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CDDP; Chromatin structure; DNA cross linking; Z DNA

Indexed keywords

CISPLATIN; DNA Z; POLYAMINE; POLYNUCLEOTIDE;

ARTICLE; BRAIN TUMOR; CANCER CELL CULTURE; CELL PROTECTION; COLONY FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DNA CROSS LINKING; DNA STRUCTURE; DRUG EFFECT; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CISPLATIN; DNA DAMAGE; DNA, NEOPLASM; DRUG SYNERGISM; GROWTH INHIBITORS; HUMANS; NUCLEIC ACID CONFORMATION; POLYAMINES; SPERMIDINE; SPERMINE; TUMOR CELLS, CULTURED;

EID: 0029986589     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Basu HS and Marton LJ: Biological and therapeutic implications of the effects of polyamines on chromatin condensation. In: Polyamines: Regulation and Molecular Interactions R.A. Casero, Ed. Molecular Biological Intelligence Unit/R.G. Landes Co., Austin (1995) pp. 101-128.
2. 5dC). Pro Natl Acad Sci USA 78:1619-1623, 1981.
3. Feuerstein BG, William LD Basu HS and Marton LJ: Implications and concepts of polyamine-nucleic acid interactions. J Cell Biochem 46: 37-47, 1991.
4. Basu HS, Schwietert HCA, Feuerstein BG and Marton LJ: Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes. Biochem J 269: 329-334, 1990.
5. Basu HS and Marton LJ: The interaction of spermine and pentamines with DNA. Biochem J 244: 243-246, 1987.
6. Basu HS Feuerstein BG Deen DF, Lubich WP, Bergeron RJ, Samejima K and Marton LJ: Correlation between the effects of polyamine analogues on DNA conformation and cell growth. Cancer Res 49: 5591-5597, 1989.
7. 14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells. Cancer Res 50: 3137-3140, 1990.
8. 14-bis(ethyl)-homospermine (BE-4-4-4) on the growth of U-251 MG and SF- 188 human brain tumor cells. Int J Cancer 48: 873-878, 1991.
9. Basu HS, Pellarin M, Feuerstein BG, Shirahata A, Samejima K, Deen DF and Marton LJ: Interaction of a polyarnine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-44-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines. Cancer Research 53: 3948-3955, 1993.
10. Basu HS, Pellarin M, Feuerstein BG, Deen DF and Marton LJ: Effects of the polyamine analogs BE-3-7-3, 3-8-3, and BE-3-8-3 on human brain tumor cell growth and survival. Anticancer Research 13: 1525-1532, 1993.
11. Basu HS, Pellarin M, Bergeron RJ, Deen DF, Marton LJ and Feuerstein BG: Design and Testing of Novel Cytototoxic Polyarnine Analogs. Cancer Research 54: 6210-6214, 1994.
12. Bergeron RJ, Hawthorne TR, Vinson JRT, Beck DE Jr and Ingeno MJ: Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells. Cancer Res 49: 2959-2964, 1989.
13. Bernacki RJ, Bergeron RJ, Porter CW: Antitumor activity of N,N′-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts. Cancer Res 52: 2424-2430 (1992).
14. Loehrer PJ and Einhorn L: Drugs five years later: cisplatin. J Ann Intern Med 100: 704-713, 1984.
15. Rosenberg B Van Camp L, Trosko JE, and Mansour VH: Platinum compounds: a new class of potent antitumor agents. Nature, 222: 385-386, 1969.
16. Rosenberg B: Platinum complex-DNA interactions and anticancer activity. Biochimie 60: 859-867, 1978.
17. 2]. Science 218: 1075-1082, 1982.
18. Pinto AL and Lippard SJ: Binding of the antitumor drug cis-diammine-dichtoroplatinum (II) (cisplatin) to DNA. Acta Biochim. Biophys. Hung 780: 167-180, 1985.
19. Rice JA, Crothers DM, Pinto AL and Lippard SJ: The major adduct of the antitumor drug cis-diamminedichloroplatinum (II) with DNA bends the duplex by approximately equal to 40 degrees towards the major groove. Proc Natl Acad Sci USA 85: 4158-4161, 1988.
20. Ushay HM, Santella RM, Caradonna JP, Grunberger D and Lippard SJ: Binding of [(dien)PtCl] Cl to poly(dG-dC)-poly(dG-dC) facilitates the B goes to Z conformational transition. Nucleic Acids Res 10: 3573-3588, 1982.
21. Malinge JM and Leng M: Reaction of cis-diammine-dichloroplatinum (II) and DNA in B or Z conformation. EMBO J 3: 1273-1279 1984.
22. Malinge JM, Ptak M and Leng M: Immunological and spectroscopic studies of poly(dG-dC).poly(dG-dC) modified by cis-diammine-dichloroplatinum(II). Nucleic Acids Res 12: 5767-5778 1984.
23. Ho J-T, and Deen DF: Prolonged hyperthermia eliminates mycoplasina from cultured human and rat brain tumor cell lines. Radiat Res 127: 339-341, 1991.
24. Oredsson SM, Deen DF and Marton LJ: Decreased cytotoxicity of cis-diamminedichloroplatinum (II) by alpha-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro. Cancer Res 42: 1296-1299, 1982.
25. Kabra PM, Lee HK, Lubich WP, and Marton LJ: Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue. J Chromatogr 380, 19-32, 1986.
26. Erickson LC, Osieka R, Sharkey NA, and Kohn KW: Measurement of DNA damage in unlabeled mammalian cells analyzed by alkaline elution and a fluormetric DNA assay. Anal. Biochem 106: 169-174, 1980.
27. Kohn KW, Ewig RAG, Erickson LC and Zwelling LA: Measurement of strand breaks and cross-links by alkaline elution. In DNA Repair (Eds. EC Friedberg and PC Hanawalt) pp. 379-401. New York: Marcel Dekker 1982.
28. Rich A, Nordheim A and Wang AH: The chemistry and biology of left-handed Z-DNA. Ann Rev Biochem 53: 791-846, 1984.
29. Ramesh N, Souchey YS and Brahmachari SK: Recognition of B and Z forms of DNA by Bscherichia coli DNA polymerase I. J Mol Biol 190: 635-638, 1986.
30. 6-methylguanine-DNA methyltransferase does not repair promutagenic O6-methylguanine residues when present in Z-DNA. J Biol Chem 260: 8711-8715, 1985.
31. Basu HS, Sturkenboom MCJM, Feuerstein BG and Marton LJ: Effect of polyamine depletion on the chromatin structure of U-87 human brain tumor cells. Biochem J 282; 723-727 (1992).
32. Foka M and Paoletti J: Interaction of cis-diamminedichloro-platinum (II) to chromatin: specificity of the drug distribution. Biochem Pharmacol 35: 3283-3291, 1986.
33. Hayes J and Scovell WM: Cis-diamminedichloro-platinum (II) modified chromatin and nucleosomal core particle. Biochim Biophys Acta 1089: 377-385, 1991.
34. Hayes J and Scovell WM: Cis-diamminedichloro-platinum (II) modified chromatin and nucleosomal core particle probed with DNase I. Biochim. Biophys. Acta 1088: 413-418, 1991.
35. Basu HS, Wright WD, Deen DF, Roti-Roti J and Marton LJ: Treatment with polyamine analog alters the state of DNA supercoiling in HeLa cell nuclei: A nucleoid halo assay Biochemistry 32: 4073-4076, 1993.
36. Smirnov IV, Feuerstein BG, Pellarin M, Marton LJ, Deen DF and Basu HS: Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triaza-nonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells. Cell Mol Biol 40: 975-980, 1994.
37. Garner M and Felsenfeld G: Effect of Z-DNA on nucleosome placement. J Mol Biol 196: 581-590, 1987.
38. Eastman A: Reevaluation of interaction of cis-dichloro(ethylenediamine)platinum (II) DNA.Biochemistry 25: 3912-3915, 1986.
39. Eastman A: Interstrand cross-links and sequence specificity in the reaction of cis-dichloro(ethylenediamine)platinum (II) with DNA. Biochemistry 24: 5027-5032, 1985.
40. Kohn KW: Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)- 1 -nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas. Cancer Res 37: 1450-1454, 1977.