메뉴 건너뛰기




Volumn 49, Issue 6, 1996, Pages 491-495

Omeprazole and lansoprazole are not inducers of cytochrome P4501A2 under conventional therapeutic conditions

Author keywords

Caffeine; CYP1A2; Enzyme induction; Lansoprazole; Omeprazole

Indexed keywords

1 METHYLURIC ACID; 1 METHYLXANTHINE; 1,7 DIMETHYLURIC ACID; 5 ACETAMIDO 6 FORMYLAMINO 3 METHYLURACIL; CAFFEINE; CYTOCHROME P450; DRUG METABOLITE; LANSOPRAZOLE; OMEPRAZOLE;

EID: 0029986312     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050055     Document Type: Article
Times cited : (26)

References (27)
  • 3
    • 0025316892 scopus 로고
    • Human cytochrome P450 isoforms
    • Farrell GC, Murray M (1990) Human cytochrome P450 isoforms. Gastroenterology 99:885-889
    • (1990) Gastroenterology , vol.99 , pp. 885-889
    • Farrell, G.C.1    Murray, M.2
  • 4
    • 0025793209 scopus 로고
    • Omeprazole and the induction of Human Cytochrome P-450. A response to concerns about potentiel adverse effects
    • Parkinson A, Hurwitz A (1991) Omeprazole and the induction of Human Cytochrome P-450. A response to concerns about potentiel adverse effects. Gastroenterology 100:1157-1164
    • (1991) Gastroenterology , vol.100 , pp. 1157-1164
    • Parkinson, A.1    Hurwitz, A.2
  • 5
    • 0021861283 scopus 로고
    • The mechanism of action of omeprazole - A survey of its inhibitory actions in vitro
    • Wallmark B, Lorentzon P, Larsson H (1985) The mechanism of action of omeprazole - a survey of its inhibitory actions in vitro. Scand J Gastroenterol 20 [Suppl 108]: 37-51
    • (1985) Scand J Gastroenterol , vol.20 , Issue.108 SUPPL. , pp. 37-51
    • Wallmark, B.1    Lorentzon, P.2    Larsson, H.3
  • 9
    • 0023227456 scopus 로고
    • A urinary metabolite ratio that reflects systemic caffeine clearance
    • Campbell ME, Spielberg SP, Kalow W (1987) A urinary metabolite ratio that reflects systemic caffeine clearance. Clin Pharmacol Ther 42:157-165
    • (1987) Clin Pharmacol Ther , vol.42 , pp. 157-165
    • Campbell, M.E.1    Spielberg, S.P.2    Kalow, W.3
  • 10
    • 0024343858 scopus 로고
    • PA (P-4501A2), the phenacetin-O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
    • PA (P-4501A2), the phenacetin-O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proc Natl Acad Sci USA 86:7696-7700
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7696-7700
    • Butler, M.A.1    Iwasaki, M.2    Guengerich, F.P.3    Kadlubar, F.F.4
  • 11
    • 0027197152 scopus 로고
    • The use of caffeine for enzyme assays: A critical appraisal
    • Kalow W, Tang BK (1993) The use of caffeine for enzyme assays: a critical appraisal. Clin Pharmacol Ther 53:503-514
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 503-514
    • Kalow, W.1    Tang, B.K.2
  • 12
    • 0025942605 scopus 로고
    • Cytochrome P4501A2 activity in man measured by caffeine metabolism: Effect of smoking, broccoli and exercise
    • Vistisen K, Loft S, Poulsen HE (1990) Cytochrome P4501A2 activity in man measured by caffeine metabolism: effect of smoking, broccoli and exercise. Adv Exp Med Biol 283:407-411
    • (1990) Adv Exp Med Biol , vol.283 , pp. 407-411
    • Vistisen, K.1    Loft, S.2    Poulsen, H.E.3
  • 17
    • 0028240671 scopus 로고
    • Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios : Coincidence with plasma clearance and breath test
    • Rost KL, Roots I (1994) Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios : coincidence with plasma clearance and breath test. Clin Pharmacol Ther 55:402-411
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 402-411
    • Rost, K.L.1    Roots, I.2
  • 18
    • 0023113788 scopus 로고
    • Biotrans-formation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P450 in human liver microsomes
    • Campbell ME, Grant DM, Inaba T, Kalow W (1987) Biotrans-formation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P450 in human liver microsomes. Drug Metab Dispo 15:237-249
    • (1987) Drug Metab Dispo , vol.15 , pp. 237-249
    • Campbell, M.E.1    Grant, D.M.2    Inaba, T.3    Kalow, W.4
  • 19
    • 0025969276 scopus 로고
    • Caffeine as a metabolic probe: Exploration of the enzyme-inducing effect of cigarette smoking
    • Kalow W, Tang BK (1991) Caffeine as a metabolic probe: exploration of the enzyme-inducing effect of cigarette smoking. Clin Pharmacol Ther 49:44-48
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 44-48
    • Kalow, W.1    Tang, B.K.2
  • 21
    • 9844222278 scopus 로고
    • Caffeine - A novel probe to assess drug effects on hepatic cytochrome P-450 activity
    • Shaw-Stiffel TA, Tang BK, Spielberg SP, Shear NH (1988) Caffeine - a novel probe to assess drug effects on hepatic cytochrome P-450 activity [Abstract]. Hepatology 8:1385
    • (1988) Hepatology , vol.8 , pp. 1385
    • Shaw-Stiffel, T.A.1    Tang, B.K.2    Spielberg, S.P.3    Shear, N.H.4
  • 24
    • 0023161812 scopus 로고
    • Drugs other than H2-receptor antagonists as clinically important inhibitors of drugs metabolism in vivo
    • Gugler R, Jensen JC (1987) Drugs other than H2-receptor antagonists as clinically important inhibitors of drugs metabolism in vivo. Pharmacol Ther 33:133-137
    • (1987) Pharmacol Ther , vol.33 , pp. 133-137
    • Gugler, R.1    Jensen, J.C.2
  • 25
    • 0026555824 scopus 로고
    • No influence of single intravenous doses of omeprazole on theophylline elimination kinetics
    • Oosterhuis B, Jonkman J, Anderson T, Zuiderwijk P (1992) No influence of single intravenous doses of omeprazole on theophylline elimination kinetics. J Clin Pharmacol 32: 470-475
    • (1992) J Clin Pharmacol , vol.32 , pp. 470-475
    • Oosterhuis, B.1    Jonkman, J.2    Anderson, T.3    Zuiderwijk, P.4
  • 27
    • 0028051743 scopus 로고
    • Specific and dose-dependent enzyme induction by omeprazole in human beings
    • Rost KL, Brösicke H, Heinmeyer G, Roots I (1994) Specific and dose-dependent enzyme induction by omeprazole in human beings. Hepatology 20:1204-1212
    • (1994) Hepatology , vol.20 , pp. 1204-1212
    • Rost, K.L.1    Brösicke, H.2    Heinmeyer, G.3    Roots, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.