Nucleoside analogs. 14. The synthesis and antitumor activity in mice of molecular combinations of 5-fluorouracil and N-(2-chloroethyl)-N-nitrosourea moieties separated by a three-carbon chain

Journal of Medicinal Chemistry

Volumn 39, Issue 7, 1996, Pages 1408-1412

  McElhinney, R Stanley ^a   McCormick, Joan E ^a   Bibby, Mike C ^b   Double, John A ^b   Radacic, Marco ^c   Dumont, Patrick ^d,e  

^a Chemical Analysis Laboratories   (Ireland)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

^c RUDER BO KOVI INSTITUTE   (Croatia)

^d JULES BORDET INSTITUTE   (Belgium)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 [3 [3 (2 CHLOROETHYL) 3 NITROSOUREIDO] 1 METHOXYPROPYL] 5 FLUOROURACIL; ANTINEOPLASTIC AGENT; B 3995; B 3996; B 3999; B 4015; B 4030; B 4083; CHLOROETHYLNITROSOUREA; FLUOROURACIL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; COLON ADENOCARCINOMA; DRUG CONFORMATION; DRUG MIXTURE; DRUG POTENCY; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; COLONIC NEOPLASMS; ETHYLNITROSOUREA; FLUOROURACIL; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NUCLEOSIDES;

EID: 0029986151     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9507237     Document Type: Article

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