Epstein-Barr virus and AIDS-related primary central nervous system lymphoma. Viral detection by immunohistochemistry, RNA in situ hybridization, and polymerase chain reaction

Clinical Neuropathology

Volumn 15, Issue 2, 1996, Pages 79-86

  Aboody Guterman, K S ^a   Hair, L S ^b   Morgello, S ^a,c  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

AIDS; CNS lymphoma

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; AUTOPSY; B CELL LYMPHOMA; BRAIN LYMPHOMA; CLINICAL ARTICLE; EPSTEIN BARR VIRUS; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; NEUROPATHOLOGY; PRIORITY JOURNAL;

ADULT; CENTRAL NERVOUS SYSTEM NEOPLASMS; FEMALE; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPHOMA, AIDS-RELATED; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION;

EID: 0029986027     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Ambinder R, Lambe B, Mann R, Hayward S, Zehnbauer B. Burns W, Charache P 1990 Oligonucleotides for polymerase chain reaction amplification and hybridization detection of Epstein-Ban virus DNA in clinical specimens. Mol Cell Probes 4: 397-407
2. Audouin J, Diebold J, Pallesen G 1992 Frequent expression of Epstein-Barr virus latent membrane protein-1 in tumour cells of Hodgkin's disease in HIV-positive patients. J Pathol 167: 381-384
3. Auperin I. Mikol J, Oksenhendler E, Thiebaut J, Brunet M, Dupont B, Morinet F 1994 Primary central nervous system malignant nonHodgkin's lymphomas from HIV-infected and non-infected patients: Expression of cellular surface proteins and Epstein-Barr viral markers. Neuropathol Appl Neurobiol 20: 243-252
4. Bashir R, Hairis N, Hochberg F, Singer R 1989 Detection of Epstein-Barr virus in CNS lymphomas by in-situ hybridization. Neurology 39: 813-817
5. Bashir R, Hochberg F, Harris N, Purtilo D 1990 Variable expression of Epstein-Barr virus genome as demonstrated by in situ hybridization in central nervous system lymphomas in immunocompromised patients. Mod Pathol 3: 429-434
6. Bashir R, Luka J, Cheloha K, Chamberlain M, Hochberg F 1993 Expression of Epstein-Barr virus proteins in primary CNS lymphoma in AIDS patients. Neurology 43: 2358-2362
7. Biggar R, Rabkin C 1992 The epidemiology of acquired immunodeficiency syndrome-related lymphomas. Curr Opin Oncol 4: 883-893
8. Bignon Y, Clavelou P, Ramos F, Jouvet A, Tommasi M, Tournilhac M, Dastugue B, Plagne R 1991 Detection of Epstein-Barr virus sequences in primary brain lymphoma without immunodeficiency. Neurology 41: 1152-1153
9. Brousset P, Meggetto F, Chittal S, Ribeau F, Arnaud J, Rubin B, Delsol G 1993 Assessment of the methods for the detection of Epstein-Barr virus nucleic acids and related gene products in Hodgkin's disease. Lab Invest 69: 483-490
10. Chang K, Flaris N, Hickey W, Johnson R, Meyer J, Weiss L 1993 Brain lymphomas of immunocompetent and immunocompromised patients: Study of the association with Epstein-Barr virus. Mod Pathol 6: 427-432
11. DeAngelis L, Wong E, Rosenblum M, Furneaux H 1992 Epstein-Barr virus in acquired immune deficiency syndrome (AIDS) and non-AIDS primary central nervous system lymphoma. Cancer 70: 1607-1611
12. Fine H, Mayer R 1993 Primary central nervous system lymphoma. Ann Intern Med 119: 1093-1104
13. Hamilton-Dutoit S, Pallesen G, Franzmann M, Karkov J, Black F, Skinhoj P, Pedersen C 1991 AIDS-related lymphoma: Histopathology, immunophenotype, and association with Epstein-Barr virus as demonstrated by in situ nucleic acid hybridization. Am J Pathol 138: 149-163
14. Henry J, Heffner R, Dillard S, Earle K, Davis R 1974 Primary malignant lymphomas of the central nervous system. Cancer 34: 1293-1302
15. Herndier B, Sanchez H, Chang K, Chen Y, Weiss L 1993 High prevalence of Epstein-Barr virus in the Reed-Stemberg cells of HIV-associated Hodgkin's disease. Am J Pathol 142: 1073-1079
16. Howe J, Sieitz J 1986 Localization of Epstein-Barr virus-encoded small RNAs by in situ hybridization. Proc Natl Acad Sci USA 83: 9006-9010
17. Iglesias-Rozas J, Bantz B, Adler T, Jautzke G, Tosth U, Lange W, Stein H, Dienemann D 1991 Cerebral lymphoma in AIDS. Clinical, radiological, neuropathological and immunopathological study. Clin Neuropathol 10: 65-72
18. Jellinger K, Radaskiewicz T, Slowik F 1975 Primary malignant lymphomas of the central nervous system in man. Acta Neuropathol (Berl) Suppl VI: 95-102
19. Klein G 1989 Viral latency and transformation: The strategy of Epstein-Barr virus. Cell 58: 5-8
20. Kyaw M, Hurren L, Evans L, Moss D, Cooper D, Benson E, Esmore D, Sculley T 1992 Expression of B-type Epstein-Barr virus in HIV-infected patients and cardiac transplant recipients. AIDS Res Hum Retrovir 8: 1869-1874
21. Levine A 1991 Lymphoma related to human immunodeficiency virus: The epidemic shifts. J Natl Cancer Inst 83: 662-663
22. List A, Greer J, Cousar J, Johnson D, Greco F, Volsky D, Purtilo D 1990 Primary brain lymphoma in the immunocompetent host: Relation to Epstein-Barr virus. Mod Pathol 3: 609-612
23. MacMahon E, Glass J, Hayward S, Mann R, Becker P, Charache P, McArthur J, Ambinder R 1991 Epstein-Barr virus in AIDS-related primary central nervous system lymphoma. Lancet 338: 969-973
24. Meeker T, Shiramizu B, Kaplan L, Herndier B, Sanchez H, Grimaldi J, Baumgartner J, Rachlin J, Feigal E, Rosenblum M, McGrath M 1991 Evidence for molecular subtypes of HIV-associated lymphoma: Division into peripheral monoclonal, polyclonal and central nervous system lymphoma. AIDS 5: 669-674
25. Moore R, Kessler H, Richman D, Flexner C, Chaisson A 1991 Non-Hodgkin's lymphoma in patients with advanced HIV infection treated with zidovudine. JAMA 265: 2208-2211
26. Morgello S 1992 Epstein-Barr and human immunodeficiency viruses in acquired immunodeficiency syndrome-related primary central nervous system lymphoma. Am J Pathol 141: 457-465
27. Morgello S, Petito C, Mouradian J 1990 Central nervous system lymphoma in the acquired immunodeficiency syndrome. Clin Neuropathol 9: 205-215
28. Nakhleh R, Manivel J, Copenhaver C. Sung J, Strickler J 1991 In situ hybridization for the detection of Epstein-Barr virus in central nervous system lymphomas. Cancer 67: 444-448
29. Paulus W, Jellinger K, Hallas C, Ott G, Müller-Hermelink H 1993 Human herpesvirus-6 and Epstein-Barr virus genome in primary cerebral lymphomas. Neurology 43: 1591-1593
30. Pluda J, Yarchoan R, Jaffe E, Feuerstein I, Solomon D, Steinberg S, Wyvill K, Raubitschek A, Katz D, Broder S 1990 Development of non-Hodgkin lymphoma in a cohort of patients with severe human immunodeficiency virus (HIV) infection on long-term antiretroviral therapy. Ann Int Med 113: 276-282
31. Rouah E, Rogers B, Wilson D, Kirkpatrick J, Buffone G 1990 Demonstration of Epstein-Barr virus in primary central nervous system lymphomas by the polymerase chain reaction and in situ hybridization. Hum Pathol 21: 545-550
32. Saito I, Servenius B, Campton T, Fox RI 1989 Detection of Epstein-Barr virus DNA by polymerase chain reaction in blood and tissue biopsies from patients with Sjogren's syndrome. J Exp Med 169, 2191-2198
33. So Y, Beckstead J, Davis R 1986 Primary central nervous system lymphoma in acquired immune deficiency syndrome: A clinical and pathological study. Ann Neurol 20: 566-572
34. Subar M, Neri A, Inghirami G, Knowles D, Dalla-Favera R 1998 Frequent c-myc oncogene activation and infrequent presence of Epstein-Barr virus genome in AIDS-associated lymphoma. Blood 72: 667-671
35. Sugden B 1989 An intricate route to immortality. Cell 57: 5-7
36. Vinters H, Anders K 1990 AIDS-related neoplasia. Neuropathology of AIDS. CRC Press, Boca Raton, pp 91-108
37. Wu T, Mann R, Epstein J, MacMahon E, Lee W, Charache P, Hayward S, Kurman R, Hayward G, Ambinder R 1991 Abundant expression of EBER1 small nuclear RNA in nasopharyngeal carcinoma: A morphologically distinctive target for detection of Epstein-Barr virus in formalin fixed, paraffin-embedded carcinoma specimens. Am J Pathol 138: 1461-1469
38. Zimmerman H 1975 Malignant lymphomas of the nervous system. Acta Neuropathol (Berl) Suppl VI: 69-74