Nitric oxide production is increased during murine vaccinia virus infection, but may not be essential for virus clearance

Virology

Volumn 217, Issue 2, 1996, Pages 470-477

  Rolph, Michael S ^a   Ramshaw, Ian A ^a   Rockett, Kirk A ^a   Ruby, Janet ^a   Cowden, William B ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

N(G) METHYLARGININE; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINIA VIRUS; VIRUS INFECTION; VIRUS TITRATION;

EID: 0029985795     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0141     Document Type: Article

References (36)

1. Adams, L. B., Franzblau, S. C., Vavrin, Z., Hibbs, J. B., and Krahenbuhl, J. L. (1991). L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae. J. Immunol. 147, 1642-1646.
2. Beckerman, K. P., Rogers, H. W., Corbett, J. A., Schreiber, R. D., McDaniel, M. L., and Unanue, E. R. (1993). Release of nitric oxide during the T cell-independent pathway of macrophage activation. J. Immunol. 150, 888-895.
3. Bi, Z., and Reiss, C. S. (1995). Inhibition of vesicular stomatitis virus infection by nitric oxide. J. Virol. 69, 2208-2213.
4. Buller, R. M. L., Holmes, K. L., Hügin, A., Frederickson, T. N., and Morse, H. C. III. (1987). Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells. Nature 328, 77-79.
5. Campbell, I. L., Samimi, A., and Chiang, C. S. (1994). Expression of the inducible nitric oxide synthase. Correlation with neuropathology and clinical features in mice with lymphocytic choriomeningitis. J. Immunol. 153, 3622-3629.
6. Chan, J., Xing, Y., Magliozzo, R. S., and Bloom, B. R. (1992). Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175, 1111-1122.
7. Croen, K. D. (1993). Evidence for an antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication. J. Clin. Invest. 91, 2446-2452.
8. Ding, A. H., Nathan, C. F., and Stuehr, D. J. (1988). Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141, 2407-2412.
9. Gazzinelli, R. T., Eltoum, I., Wynn, T. A., and Sher, A. (1993). Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation. J. Immunol. 151, 3672-3681.
10. Granger, D. L., Hibbs, J. B., Perfect, J. R., and Durack, D. T. (1988). Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages. J. Clin. Invest. 81, 1129-1136.
11. Green, S. J., Nacy, C. A., Schreiber, R. D., Granger, D. L., Crawford, R. M., Meltzer, M. S., and Fortier, A. H. (1993). Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice. Infect. Immun. 61, 689-698.
12. Harris, N., Buller, R. M. L., and Karupiah, G. (1995). Gamma interferon-induced, nitric oxide-mediated inhibition of vaccinia virus replication. J. Virol. 69, 910-915.
13. Huang, S., Hendriks, W., Althage, A., Hemmi, S., Bluethmann, H., Kamijo, R., Vilcek, J., Zinkernagel, R. M., and Aguet, M. (1993). Immune response in mice that lack the interferon-γ receptor. Science 259, 1742-1745.
14. James, S. L., and Glaven, J. (1989). Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. J. Immunol. 143, 4208-4212.
15. Karupiah, G., and Harris, N. (1995). Inhibition of viral replication by nitric oxide and its reversal by ferrous sulfate and tricarboxylic acid cycle metabolites. J. Exp. Med. 181, 2171-2179.
16. Karupiah, G., Xie, Q. W., Buller, R. M. L., Nathan, C., Duarte, C., and MacMicking, J. D. (1993). Inhibition of viral replication by interferon-gamma induced nitric oxide synthase. Science 261, 1445-1448.
17. Langermans, J. A. M., Vanderhulst, M. E. B., Nibbering, P. H., Hiemstra, P. S., Fransen, L., and van Furth, R. (1992). IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha. J. Immunol. 148, 568-574.
18. Leist, T. P., Eppler, M., and Zinkernagel, R. M. (1989). Enhanced virus replication and inhibition of lymphocytic choriomeningitis virus disease in anti-gamma interferon-treated mice. J. Virol. 63, 2813-2819.
19. Liew, F. Y., Millott, S., Parkinson, C., Palmer, R. M. J., and Moncada, S. (1990). Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J. Immunol. 144, 4794-4797.
20. MacMicking, J. D., Nathan, C., Hom, G., Chartrain, N., Fletcher, D. S., Trumbauer, M., Stevens, K., Xie, Q., Sokol, K., Hutchinson, N., Chen, H., and Mudgett, J. S. (1995). Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81, 641-650.
21. Muñoz-Fernández, M. A., Fernández, M. A., and Fresno, M. (1992). Synergism between tumor necrosis factor-α and interferon-γ on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. Eur. J. Immunol. 22, 301-307.
22. Nussler, A. K., and Billiar, T. R. (1993). Inflammation, immunoregulation, and inducible nitric oxide synthase. J. Leuk. Biol. 54, 171-178.
23. G-mono-, di-, and trimethylated arginines. Acta Biochim. Biophys. Acad. Sci. Hung. 12, 191-195.
24. Ramshaw, I., Ruby, J., Ramsay, A., Ada, G., and Karupiah, G. (1992). Expression of cytokines by recombinant vaccinia viruses: A model for studying cytokines in virus infections in vivo. Immunol. Rev. 127, 157-182.
25. Rockett, K. A., Awburn, M. M., Aggarwal, B. B., Cowden, W. B., and Clark, I. A. (1992). In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin, and interleukin-1-possible roles in malaria. Infect. Immun. 60, 3725-3730.
26. Rockett, K. A., Awburn, M. M., Rockett, E. J., Cowden, W. B., and Clark, I. A. (1994). Possible role of nitric oxide in malarial immunosuppression. Parasite Immunol. 16, 243-249.
27. Rottenberg, M. E., Sporrong, L., Persson, I., Wigzell, H., and Örn, A. (1995). Cytokine gene expression during infection of mice lacking CD4 and/or CD8 with Trypanosoma cruzi. Scand. J. Immunol. 41, 164-170.
28. + T cells is dependent on interferon-γ. Lymphokine Cytokine Res. 10, 353-358.
29. Ruby, J., Sedger, L., and Ramshaw, I. (1993). Cytokine production in virus-infected mice: A single cell analysis. Viral Immunol. 6, 125-134.
30. Samuel, C. E. (1991). Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183, 1-11.
31. + T cells. J. Exp. Med. 180, 353-358.
32. Summersgill, J. T., Powell, L. A., Buster, B. L., Miller, R. D., and Ramirez, J. A. (1992). Killing of Legionella pneumophila by nitric oxide in γ-interferon-activated macrophages. J. Leuk. Biol. 52, 625-629.
33. Tao, X., and Stout, R. D. (1993). T cell-mediated cognate signaling of nitric oxide production by macrophages. Requirements for macrophage activation by plasma membranes isolated from T cells. Eur. J. Immunol. 23, 2916-2921.
34. Tripp, C. S., Wolf, S. F., and Unanue, E. R. (1993). Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc. Natl. Acad. Sci. USA 90, 3725-3729.
35. Wei, X., Charles, I. G., Smith, A., Ure, J., Feng, G., Huang, F., Xu, D., Muller, W., Moncada, S., and Liew, F. Y. (1995). Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 375, 408-411.
36. Zheng, Y. M., Schäfer, M. K., Weihe, E., Sheng, H., Corisdeo, S., Fu, Z. F., Koprowski, H., and Dietzschold, B. (1993). Severity of neurological signs and degree of inflammatory lesions in the brains of rats with Borna disease correlate with the induction of nitric oxide synthase. J. Virol. 67, 5786-5791.