A polymorphic dinucleotide repeat in the human dopamine D5 receptor gene promoter

Neuroscience Letters

Volumn 205, Issue 3, 1996, Pages 173-176

  Beischlag, Timothy V ^a   Nam, Diane ^a   Ulpian, Carla ^a   Seeman, Philip ^a,b   Niznik, Hyman B ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

G protein coupled receptor; Huntington's disease; Schizophrenia; Transcription

Indexed keywords

DOPAMINE RECEPTOR; RECEPTOR SUBTYPE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; PRIORITY JOURNAL; SCHIZOPHRENIA;

EID: 0029985656     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12416-2     Document Type: Article

References (17)

1. Beischlag, T.V., Marchese, A., Meador-Woodruff, J.H., Damask, S.P., O'Dowd, B.F., Tyndale, R.F., Van Tol, H.H.M., Seeman, P. and Niznik, H.B., The human dopamine D5 receptor gene: cloning and characterization of the 5′-flanking and promoter region, Biochemistry, 34 (1995) 5960-5970.
2. Bergson, C., Mrzijak, L., Lidow, M.S., Goldman-Rakic, P.S. and Levenson, R., Characterization of subtype-specific antibodies to the human D5 dopamine receptor: studies in primate brain and transfected mammalian cells, Proc. Natl. Acad. Sci. USA, 92 (1995) 3468-3472.
3. Grandy, D.K., Zhang, Y., Bouvier, C., Zhou, Q.-Y., Johnson, R.A., Allen, L., Buck, K., Bunzow, J.R., Salon, J. and Civelli, O., Multiple human D5 dopamine receptor genes: a functional receptor and two pseudogenes, Proc. Natl. Acad. Sci. USA, 88 (1991) 9175-9179.
4. Kahn, R.S. and Davis, K.L., New developments in dopamine and schizophrenia. In F.E. Bloom and D.J. Kupfer (Eds.), Psychopharmacology: the Fourth Generation of Progress, Raven Press, NY, 1995, 1193-1203.
5. Lee, T., Seeman, P., Rajput, A., Farley, I.J. and Hornykiewicz, O., Receptor basis for dopaminergic supersensitivity in Parkinson's disease, Nature, 273 (1978) 59-61.
6. 3H]apomorphine in schizophrenic brains, Nature, 274 (1978) 897-900.
7. Marchese, A., Beischlag, T.V., Nguyen, T., Niznik, H.B., Weinshank, R.L., George, S.R. and O'Dowd, B.F., Two gene duplication events in the human and primate dopamine D5 receptor gene family, Gene, 154 (1995) 153-158.
8. Nguyen, T., Bard, J., Jin, H., Taruscio, D., Ward, D.C., Kennedy, J.L., Weinshank, R.L., Seeman, P. and O'Dowd, B.F., Dopamine D5 receptor human pseudogenes, Gene, 109 (1991) 211-218.
9. Nguyen, T., Sunahara, R.K., Marchese, A., Van Tol, H.H.M., Seeman, P. and O'Dowd, B.F., Transcription of a human dopamine D5 pseudogene, Biochem. Biophys. Res. Commun., 181 (1991) 16-21.
10. Niznik, H.B and Van Tol, H.H.M., Dopamine receptor genes: new tools for molecular psychiatry, J. Psychiatry Neurosci., 17 (1992) 158-180
11. Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K. and Sekiya, T., Detection of polymorphisms of DNA by gel electrophoresis as single-strand conformation polymorphisms, Proc. Natl. Acad. Sci. USA, 86 (1989) 2766-2770.
12. Sherrington, R., Mankoo, B., Attwood, J., Kalsi, G., Curtis, D., Buetow, K., Povey, S. and Gurling, H., Cloning of the human dopamine D5 receptor gene and identification of a highly polymorphic microsatellite for the DRD5 locus that shows tight linkage to the chromosome 4p reference marker RAF1P1, Genomics, 18 (1993) 423-425.
13. Sobell, J.L., Lind, T.J., Sigurdson, D.C., Zald, D.H., Snitz, B.E., Grove, W.M., Hestorn, L.L. and Sommer, S.S., The D5 dopamine receptor gene in schizophrenia: identification of a nonsense change and multiple missense changes but lack of association with disease, Hum. Mol. Genet., 4 (1995) 507-514.
14. Sommer, S.S., Sobell, J.L and Heston, L.L., A common exonic polymorphism in the human D5 dopamine receptor gene. Hum. Genet., 92 (1993) 633-634.
15. Sunahara, R.K., Guan, H.C., O'Dowd, B.F., Seeman, P., Laurier, L.G., Ng, G., George, S.R., Van Tol, H.H.M. and Niznik, H.B., Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1, Nature (London), 350 (1991) 614-619.
16. Tournamille, C., Colin, Y., Cartron, J.P. and Le Van Kim, C., Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals, Nature Genet., 10 (1995) 224-228.
17. Weinshank, R.L., Adham, N., Macchi, M., Olsen, M.A., Branchek, T.A. and Hartig, P.R., Molecular cloning and characterization of a high affinity dopamine receptor and its pseudogenes, J. Biol. Chem., 266 (1991) 22427-22435.