Analysis of plasma metabolites during human PET studies with three receptor ligands, [11C]YM-09151-2, [11C]doxepin and [11C]pyrilamine

Tohoku Journal of Experimental Medicine

Volumn 178, Issue 2, 1996, Pages 129-136

  Ishiwata, Kiichi ^a,c   Yanai, Kazuhiko ^b   Iwata, Ren ^a   Takahashi, Toshihiro ^a   Hatazawa, Jun ^a   Itoh, Masatoshi ^a   Watabe, Koji ^a   Watanabe, Takehiko ^b   Ido, Tatsuo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Carbon 11; Human plasma metabolites; Positron emission tomography (PET); Receptor ligand

Indexed keywords

CARBON 11; DOXEPIN; DRUG METABOLITE; EMONAPRIDE; MEPYRAMINE;

ADULT; ARTICLE; DRUG CLEARANCE; DRUG METABOLISM; DRUG PROTEIN BINDING; EPILEPSY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY;

ADULT; AGED; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BENZAMIDES; BIOTRANSFORMATION; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE ANTAGONISTS; DOXEPIN; FEMALE; HISTAMINE H1 ANTAGONISTS; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; PROTEIN BINDING; PYRILAMINE; RECEPTORS, DOPAMINE D2; RECEPTORS, HISTAMINE H1; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0029985609     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.178.129     Document Type: Article

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