Identification of thyroid hormone conjugates produced by isolated hepatocytes and excreted in bile of rainbow trout, Oncorhynchus mykiss

General and Comparative Endocrinology

Volumn 101, Issue 2, 1996, Pages 145-154

  Finnson, K W ^a   Eales, J G ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

THYROID HORMONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE FLOW; CELL ISOLATION; CONTROLLED STUDY; DEIODINATION; DIET RESTRICTION; DRUG CONJUGATION; ENTEROHEPATIC CIRCULATION; HORMONE DETERMINATION; LIVER CELL; LIVER MICROSOME; NONHUMAN; ONCORHYNCHUS; PRIORITY JOURNAL; RAINBOW TROUT; SULFATION;

EID: 0029985262     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1006/gcen.1996.0016     Document Type: Article

References (19)

1. Bres, O., and Eales, J. G. (1988). High-affinity, limited-capacity triiodothyronine binding sites in nuclei from various tissues in the rainbow trout, Salmo gairdneri. Gen. Comp. Endocrinol. 69, 71-79.
2. DiStefano, J. J. (1988). Excretion, metabolism and enterohepatic circulation pathways and their role in overall thyroid hormone regulation in the rat. Am. Zool. 28, 373-387.
3. Eales, J. G. (1985). The peripheral metabolism of thyroid hormones and regulation of thyroidal status in poikilotherms. Can. J. Zool. 63, 1217-1231.
4. 3 in rainbow trout, Salmo gairdneri. Gen. Comp. Endocrinol. 50, 395-406.
5. Eales, J. G., and Brown, S. B. (1993). Measurement and regulation of thyroidal status in teleost fish. Rev. Fish Biol. Fish. 3, 299-347.
6. Eelkman Rooda, S. J., Otten, M. H., van Loon, M.A. C., Kaptein, E., and Visser, T. J. (1989). Metabolism of triiodothronine in rat hepatocytes. Endocrinology 125, 2187-2197.
7. Higgs, D. A., Fagerlund, U.H. M., Eales, J. G., and McBride, J. R. (1992). Application of thyroid and steroid hormones as anabolic agents in fish culture. Comp. Biochem. Physiol. 73B, 143-176.
8. 4 5′-deiodinating systems in various tissues of the rainbow trout, Oncorhynchus mykiss. Gen. Comp. Endocrinol. 86, 313-322.
9. McNabb, P.M. A. (1992). 'Thyroid Hormones,' pp. 283 Prentice-Hall, Englewood Cliffs, NJ.
10. Mol, J., and Visser, T. J. (1985). Synthesis and some properties of sulfate esters and sulfamates of iodothyronines. Endocrinology 117, 1-7.
11. Moon, T. W., Walsh, P. J., and Mommsen, T. P., (1985). Fish hepatocytes: A model metabolic system. Can. J. Fish. Aquat. Sci. 42, 1772-1782.
12. Osborn, R. H., and Simpson, T. H. (1969). Thyroxine metabolism in the plaice, Pleuronectes platessa. Gen. Comp. Endocrinol. 13, 524.
13. Riley, W. W., and Eales, J. G. (1993). Characterization of L-thyroxine transport into hepatocytes isolated from juvenile rainbow trout, Oncorhynchus mykiss. Gen. Comp. Endocrinol. 90, 31-42.
14. Rutgers, M., Bonthuis, F., de Herder, W. W., and Visser, T. J. (1987). Accumulation of plasma triiodothyronine sulfate in rats treated with propylthiouracil. J. Clin. Invest. 80, 758-762.
15. Scott, A. P., and Canario, A.V. M. (1992). 17a,20β-dihydroxy-4-pregnen-3-one 20-sulphate: A major new metabolite of the teleost oocyte maturation-inducing steroid. Gen. Comp. Endocrinol. 85, 91-100.
16. Sinclair, D.A. R., and Eales, J. G. (1972). lodothyronine-glucuronide conjugates in the bile of brook trout, Salvelinus fontinalis and other freshwater teleosts. Gen. Comp. Endocrinol. 19, 552-559.
17. Sweeting, R. M., and Eales, J. G. (1992). HPLC analysis of in vitro deiodination products of thyroid hormones in the rainbow trout, Oncorhynchus mykiss. Gen. Comp. Endocrinol. 85, 367-375.
18. Visser, T. J. (1990). Importance of deiodination and conjugation in the hepatic metabolism of thyroid hormone. In 'The Thyroid Gland' (Greer, M. A., Ed.), pp. 255-283. Raven Press, New York.
19. Whitaker, A., and Eales, J. G. (1993). Comparison of 3,5,3′-triiodo-L-thyronine and L-thyroxine from the intestinal lumen of fasted rainbow trout, Oncorhynchus mykiss. Fish Physiol. Biochem. 10,431-441.