-
1
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen LA, Peltomäki P, Leach FS, Sistonen P, Pylkkänen L, Mecklin J-P, Järvinen H, Powell SM, Jen J, Hamilton SR, Petersen GM, Kinzler KW, Vogelstein B, de la Chapelle A (1993): Clues to the pathogenesis of familial colorectal cancer. Science 260:812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomäki, P.2
Leach, F.S.3
Sistonen, P.4
Pylkkänen, L.5
Mecklin, J.-P.6
Järvinen, H.7
Powell, S.M.8
Jen, J.9
Hamilton, S.R.10
Petersen, G.M.11
Kinzler, K.W.12
Vogelstein, B.13
De La Chapelle, A.14
-
2
-
-
0028226295
-
Replication errors in benign and malignant tumors from hereditary non-polyposis colorectal cancer patients
-
Aaltonen LA, Peltomäki P, Mecklin J-P, Järvinen H, Jass JR, Green JS, Lynch HT, Watson P, Tallqvist G, Juhola M, Sistonen P, Hamilton SR, Kinzler KW, Vogelstein B, de la Chapelle A (1994): Replication errors in benign and malignant tumors from hereditary non-polyposis colorectal cancer patients. Cancer Res 54:1645-1648.
-
(1994)
Cancer Res
, vol.54
, pp. 1645-1648
-
-
Aaltonen, L.A.1
Peltomäki, P.2
Mecklin, J.-P.3
Järvinen, H.4
Jass, J.R.5
Green, J.S.6
Lynch, H.T.7
Watson, P.8
Tallqvist, G.9
Juhola, M.10
Sistonen, P.11
Hamilton, S.R.12
Kinzler, K.W.13
Vogelstein, B.14
De La Chapelle, A.15
-
3
-
-
0028301559
-
Cancer of the colon and rectum in the West Midlands, 1957-1981
-
Allum WH, Slaney G, McConkey CC, Powell J (1994): Cancer of the colon and rectum in the West Midlands, 1957-1981. Br J Surg 81:1060-1063.
-
(1994)
Br J Surg
, vol.81
, pp. 1060-1063
-
-
Allum, W.H.1
Slaney, G.2
McConkey, C.C.3
Powell, J.4
-
4
-
-
0022642727
-
Segregation analysis of hereditary nonpolyposis colorectal cancer
-
Bailey-Wilson JE, Elston RC, Schuelke GS, Kimberling W, Albano W, Lynch JF, Lynch HT (1986): Segregation analysis of hereditary nonpolyposis colorectal cancer. Genet Epidemiol 3:27-38.
-
(1986)
Genet Epidemiol
, vol.3
, pp. 27-38
-
-
Bailey-Wilson, J.E.1
Elston, R.C.2
Schuelke, G.S.3
Kimberling, W.4
Albano, W.5
Lynch, J.F.6
Lynch, H.T.7
-
5
-
-
0029099989
-
Male mice defective in the mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
-
Baker SM, Bronner E, Zhang L, Plug AW, Robatzek M, Warren G, Elliott EA, Yu J, Ashley T, Arnheim N, Flavell RA, Liskay RM (1995): Male mice defective in the mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell 82:309-319.
-
(1995)
Cell
, vol.82
, pp. 309-319
-
-
Baker, S.M.1
Bronner, E.2
Zhang, L.3
Plug, A.W.4
Robatzek, M.5
Warren, G.6
Elliott, E.A.7
Yu, J.8
Ashley, T.9
Arnheim, N.10
Flavell, R.A.11
Liskay, R.M.12
-
6
-
-
0027276469
-
Tumour spectrum in hereditary non-polyposis colorectal cancer and in families with "suspected HNPCC." A population-based study in northern Italy
-
Benatti P, Sassatelli R, Roncucci L, Pedroni M, Fante R, Di Gregorio C, Losi L, Gelmini R, Ponz de Leon M (1993): Tumour spectrum in hereditary non-polyposis colorectal cancer and in families with "suspected HNPCC." A population-based study in northern Italy. Int J Cancer 54:371-377.
-
(1993)
Int J Cancer
, vol.54
, pp. 371-377
-
-
Benatti, P.1
Sassatelli, R.2
Roncucci, L.3
Pedroni, M.4
Fante, R.5
Di Gregorio, C.6
Losi, L.7
Gelmini, R.8
Ponz De Leon, M.9
-
7
-
-
0028224645
-
Mutator phenotypes in human colorectal carcinoma cell lines
-
Bhattacharyya NP, Skandalis A, Ganesh A, Groden J, Meuth M (1994): Mutator phenotypes in human colorectal carcinoma cell lines. Proc Natl Acad Sci USA 91:6319-6323.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6319-6323
-
-
Bhattacharyya, N.P.1
Skandalis, A.2
Ganesh, A.3
Groden, J.4
Meuth, M.5
-
9
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
Bos JL (1989): ras oncogenes in human cancer: A review. Cancer Res 49:4682-4689.
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
10
-
-
0029007870
-
DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines
-
Branch P, Hampson R, Karran P (1995): DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res 55:2304-2309.
-
(1995)
Cancer Res
, vol.55
, pp. 2304-2309
-
-
Branch, P.1
Hampson, R.2
Karran, P.3
-
11
-
-
0028221943
-
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
-
Bronner CE, Baker SM, Morrison PT, Warren G, Smith LG, Lescoe MK, Kane M, Earabino C, Lipford J, Lindblom A, Tannergard P, Bollag RJ, Godwin AR, Ward DC, Nordenskjøld M, Fishel R, Kolodner R, Liskay RM (1994): Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368:258-261.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
Warren, G.4
Smith, L.G.5
Lescoe, M.K.6
Kane, M.7
Earabino, C.8
Lipford, J.9
Lindblom, A.10
Tannergard, P.11
Bollag, R.J.12
Godwin, A.R.13
Ward, D.C.14
Nordenskjøld, M.15
Fishel, R.16
Kolodner, R.17
Liskay, R.M.18
-
12
-
-
0028299319
-
Microsatellite instability in endometrial carcinoma
-
Burks RT, Kessis TD, Cho KR, Hedrick L (1994): Microsatellite instability in endometrial carcinoma. Oncogene 9:1163-1166.
-
(1994)
Oncogene
, vol.9
, pp. 1163-1166
-
-
Burks, R.T.1
Kessis, T.D.2
Cho, K.R.3
Hedrick, L.4
-
13
-
-
0021843777
-
Dominant inheritance of adenomatous colonic polyps and colorectal cancer
-
Burt RW, Bishop TD, Cannon LA, Dowdle MA, Lee RG, Skolnick MH (1985): Dominant inheritance of adenomatous colonic polyps and colorectal cancer. N Engl J Med 312:1540-1544.
-
(1985)
N Engl J Med
, vol.312
, pp. 1540-1544
-
-
Burt, R.W.1
Bishop, T.D.2
Cannon, L.A.3
Dowdle, M.A.4
Lee, R.G.5
Skolnick, M.H.6
-
14
-
-
0023753017
-
Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers
-
Cannon-Albright L, Skolnick MH, Bishop TD, Lee RG, Burt RW (1988): Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers. N Engl J Med 319:533-537.
-
(1988)
N Engl J Med
, vol.319
, pp. 533-537
-
-
Cannon-Albright, L.1
Skolnick, M.H.2
Bishop, T.D.3
Lee, R.G.4
Burt, R.W.5
-
15
-
-
0023277492
-
New phenotypic aspects in a family with Lynch syndrome II
-
Cristofaro G, Lynch HT, Caruso ML, Attolini A, Matteo GI, Giorgio P, Senatore S, Argentieri A, Sbano E, Fusaro R, Giorgio I (1987): New phenotypic aspects in a family with Lynch syndrome II. Cancer 60:51-58.
-
(1987)
Cancer
, vol.60
, pp. 51-58
-
-
Cristofaro, G.1
Lynch, H.T.2
Caruso, M.L.3
Attolini, A.4
Matteo, G.I.5
Giorgio, P.6
Senatore, S.7
Argentieri, A.8
Sbano, E.9
Fusaro, R.10
Giorgio, I.11
-
16
-
-
0028030581
-
Identification of intragenic mutations in the von Hippel-Lindau disease tumor suppressor gene and correlation with disease phenotype
-
Crossey PA, Richards FM, Foster K, Green JS, Prowse A, Latif F, Lerman MI, Zbar B, Affara NA, Ferguson-Smith MA, Maher ER (1994): Identification of intragenic mutations in the von Hippel-Lindau disease tumor suppressor gene and correlation with disease phenotype. Hum Mol Genet 3:1303-1308.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1303-1308
-
-
Crossey, P.A.1
Richards, F.M.2
Foster, K.3
Green, J.S.4
Prowse, A.5
Latif, F.6
Lerman, M.I.7
Zbar, B.8
Affara, N.A.9
Ferguson-Smith, M.A.10
Maher, E.R.11
-
17
-
-
0028859670
-
+ colorectal tumours
-
+ colorectal tumours. Nature Genet 9:10-11.
-
(1995)
Nature Genet
, vol.9
, pp. 10-11
-
-
Da Costa, L.T.1
Liu, B.2
El-Diery, W.S.3
Hamilton, S.R.4
Kinzler, K.W.5
Vogelstein, B.6
Markowitz, S.7
Willson, J.K.V.8
De La Chapelle, A.9
Downey, K.M.10
So, A.G.11
-
18
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
-
De Wind N, Dekker M, Berns A, Radman M, te Riele H (1995): Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 82:321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
De Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
Te Riele, H.5
-
19
-
-
0029070143
-
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
-
Drummon JT, Li G-M, Longley MJ, Modrich P (1995): Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science 268:1909-1912.
-
(1995)
Science
, vol.268
, pp. 1909-1912
-
-
Drummon, J.T.1
Li, G.-M.2
Longley, M.J.3
Modrich, P.4
-
20
-
-
0027433563
-
Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families
-
Easton DF, Bishop DT, Ford D, Crockford GP, Breast Cancer Linkage Consortium (1993): Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families. Am J Hum Genet 52:678-701.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 678-701
-
-
Easton, D.F.1
Bishop, D.T.2
Ford, D.3
Crockford, G.P.4
-
21
-
-
0028887597
-
Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer
-
Eshleman JR, Lang EZ, Bowerfind GK, Parsons R, Vogelstein B, Wilson JK, Veigl ML, Sedwick WD, Markowitz SD (1995): Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene 10:33-37.
-
(1995)
Oncogene
, vol.10
, pp. 33-37
-
-
Eshleman, J.R.1
Lang, E.Z.2
Bowerfind, G.K.3
Parsons, R.4
Vogelstein, B.5
Wilson, J.K.6
Veigl, M.L.7
Sedwick, W.D.8
Markowitz, S.D.9
-
22
-
-
0027269844
-
Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction
-
Fang W-H, Modrich P (1993): Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction. J Biol Chem 268:11838-11844.
-
(1993)
J Biol Chem
, vol.268
, pp. 11838-11844
-
-
Fang, W.-H.1
Modrich, P.2
-
23
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearson ER, Vogelstein B (1990): A genetic model for colorectal tumorigenesis. Cell 61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearson, E.R.1
Vogelstein, B.2
-
24
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R, Lescoe MK, Rao MRS, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R (1993): The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75:1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.S.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
25
-
-
0023204649
-
Recognition and treatment of patients with hereditary non-polyposis colorectal cancer
-
Fitzgibbons RJ, Lynch HT, Stanislav GV, Watson PA, Lanspa SJ, Markus SN, Smyrk T, Kriegler MD, Lynch JF (1987): Recognition and treatment of patients with hereditary non-polyposis colorectal cancer. Ann Surg 206:289-294.
-
(1987)
Ann Surg
, vol.206
, pp. 289-294
-
-
Fitzgibbons, R.J.1
Lynch, H.T.2
Stanislav, G.V.3
Watson, P.A.4
Lanspa, S.J.5
Markus, S.N.6
Smyrk, T.7
Kriegler, M.D.8
Lynch, J.F.9
-
26
-
-
0026547211
-
Hereditary nonpolyposis colorectal cancer: Diploid malignancies with prolonged survival
-
Frei JV (1992): Hereditary nonpolyposis colorectal cancer: Diploid malignancies with prolonged survival. Cancer 69:1108-1111.
-
(1992)
Cancer
, vol.69
, pp. 1108-1111
-
-
Frei, J.V.1
-
27
-
-
0024328152
-
Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene
-
Fujii H, Shimada T (1989): Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J Biol Chem 264:10057-10064.
-
(1989)
J Biol Chem
, vol.264
, pp. 10057-10064
-
-
Fujii, H.1
Shimada, T.2
-
28
-
-
0028065148
-
Adequacy of lymphadenectomy in laparoscopic-assisted colectomy for colorectal cancer: A preliminary report
-
Gray D, Lee H, Schlinkert R, Beart RW Jr (1994): Adequacy of lymphadenectomy in laparoscopic-assisted colectomy for colorectal cancer: A preliminary report. J Surg Oncol 57:8-10.
-
(1994)
J Surg Oncol
, vol.57
, pp. 8-10
-
-
Gray, D.1
Lee, H.2
Schlinkert, R.3
Beart Jr., R.W.4
-
29
-
-
0027401792
-
Mutational analysis of patients with adenomatous polyposis: Identical inactivating mutations in unrelated individuals
-
Groden J, Gelbert L, Thliveris A, Nelson L, Robertson M, Joslyn G, Samowitz W, Spirio L, Carlson M, Burt R, Leppert M, White R (1993): Mutational analysis of patients with adenomatous polyposis: Identical inactivating mutations in unrelated individuals. Am J Hum Genet 52:263-272.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 263-272
-
-
Groden, J.1
Gelbert, L.2
Thliveris, A.3
Nelson, L.4
Robertson, M.5
Joslyn, G.6
Samowitz, W.7
Spirio, L.8
Carlson, M.9
Burt, R.10
Leppert, M.11
White, R.12
-
30
-
-
0002837873
-
Migrant studies
-
Schottenfeld D, Fraumeni JF (eds): Philadelphia: W.B. Saunders
-
Haenszel W (1982): Migrant studies. In Schottenfeld D, Fraumeni JF (eds): "Cancer Epidemiology and Prevention." Philadelphia: W.B. Saunders, pp 194-207.
-
(1982)
Cancer Epidemiology and Prevention
, pp. 194-207
-
-
Haenszel, W.1
-
31
-
-
0025613812
-
Linkage of early-onset familial breast cancer to chromosome 17q21
-
Hall JM, Lee MK, Mewman B, Morrow J, Anderson L, Huey B, King M-C (1990): Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250:1684-1698.
-
(1990)
Science
, vol.250
, pp. 1684-1698
-
-
Hall, J.M.1
Lee, M.K.2
Mewman, B.3
Morrow, J.4
Anderson, L.5
Huey, B.6
King, M.-C.7
-
32
-
-
0028970197
-
The molecular basis of Turcot's syndrome
-
Hamilton SR, Liu B, Parsons RE, Papadopoulos N, Jen J, Powell SM, Krush AJ, Berk T, Cohen Z, Tetu B, Burger PC, Wood PA, Taqi F, Booker SV, Petersen GM, Offerhaus GJA, Tersmette AC, Giardiello FM, Vogelstein B, Kanzler KW (1995): The molecular basis of Turcot's syndrome. N Engl J Med 332:839-847.
-
(1995)
N Engl J Med
, vol.332
, pp. 839-847
-
-
Hamilton, S.R.1
Liu, B.2
Parsons, R.E.3
Papadopoulos, N.4
Jen, J.5
Powell, S.M.6
Krush, A.J.7
Berk, T.8
Cohen, Z.9
Tetu, B.10
Burger, P.C.11
Wood, P.A.12
Taqi, F.13
Booker, S.V.14
Petersen, G.M.15
Offerhaus, G.J.A.16
Tersmette, A.C.17
Giardiello, F.M.18
Vogelstein, B.19
Kanzler, K.W.20
more..
-
33
-
-
0027363208
-
Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer
-
Han H-J, Yanagisawa A, Kato Y, Park J-G, Nakamura Y (1993): Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res 53:5087-5089.
-
(1993)
Cancer Res
, vol.53
, pp. 5087-5089
-
-
Han, H.-J.1
Yanagisawa, A.2
Kato, Y.3
Park, J.-G.4
Nakamura, Y.5
-
34
-
-
0028966917
-
Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC)
-
Han H-J, Maruyama M, Baba S, Park J-G, Nakamura Y (1995): Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC). Hum Mol Genet 4:237-242.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 237-242
-
-
Han, H.-J.1
Maruyama, M.2
Baba, S.3
Park, J.-G.4
Nakamura, Y.5
-
35
-
-
0028152314
-
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
-
Hemminki A, Peltomäki P, Mecklin J-P, Järvinen H, Salovaara R, Lahti MN, de la Chapelle A, Aaltonen LA (1994): Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nat Genet 8:405-410.
-
(1994)
Nat Genet
, vol.8
, pp. 405-410
-
-
Hemminki, A.1
Peltomäki, P.2
Mecklin, J.-P.3
Järvinen, H.4
Salovaara, R.5
Lahti, M.N.6
De La Chapelle, A.7
Aaltonen, L.A.8
-
36
-
-
0025340001
-
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
-
Holmes J Jr, Clark S, Modrich P (1990): Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc Natl Acad Sci USA 87:5837-5841.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5837-5841
-
-
Holmes Jr., J.1
Clark, S.2
Modrich, P.3
-
37
-
-
0028080973
-
Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes
-
Horii A, Han H-J, Sasaki S, Shimada M, Nakamura Y (1994): Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes. Biochem Biophys Res Commun 204:1257-1264.
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 1257-1264
-
-
Horii, A.1
Han, H.-J.2
Sasaki, S.3
Shimada, M.4
Nakamura, Y.5
-
38
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M (1993): Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363:558-561.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
39
-
-
0026511623
-
Evolution of hereditary non-polyposis colorectal cancer
-
Jass JR, Stewart SM (1992): Evolution of hereditary non-polyposis colorectal cancer. Gut 33:783-786.
-
(1992)
Gut
, vol.33
, pp. 783-786
-
-
Jass, J.R.1
Stewart, S.M.2
-
40
-
-
0027532034
-
Short direct repeats flanking deletions, and duplicating insertions in p53 gene in human cancers
-
Jego N, Thomas G, Hamelin R (1993): Short direct repeats flanking deletions, and duplicating insertions in p53 gene in human cancers. Oncogene 8:209-213.
-
(1993)
Oncogene
, vol.8
, pp. 209-213
-
-
Jego, N.1
Thomas, G.2
Hamelin, R.3
-
41
-
-
0025941471
-
Identification of deletion mutations and three new genes at the familial polyposis locus
-
Joslyn G, Carlson M, Thliveris A, Albertsen H, Gelbert L, Samowitz W, Groden J, Stevens J, Spirio L, Robertson M, Sargeant L, Krapcho K, Wolff E, Burt R, Hughes JP, Warrington J, McPherson J, Wasmuth J, Le Paslier D, Abderrahim H, Cohen D, Leppert M, White R (1991): Identification of deletion mutations and three new genes at the familial polyposis locus. Cell 66:601-613.
-
(1991)
Cell
, vol.66
, pp. 601-613
-
-
Joslyn, G.1
Carlson, M.2
Thliveris, A.3
Albertsen, H.4
Gelbert, L.5
Samowitz, W.6
Groden, J.7
Stevens, J.8
Spirio, L.9
Robertson, M.10
Sargeant, L.11
Krapcho, K.12
Wolff, E.13
Burt, R.14
Hughes, J.P.15
Warrington, J.16
McPherson, J.17
Wasmuth, J.18
Le Paslier, D.19
Abderrahim, H.20
Cohen, D.21
Leppert, M.22
White, R.23
more..
-
42
-
-
0025753552
-
How prevalent is cancer family syndrome?
-
Kee F, Collins BJ (1991): How prevalent is cancer family syndrome? Gut 32:509-512.
-
(1991)
Gut
, vol.32
, pp. 509-512
-
-
Kee, F.1
Collins, B.J.2
-
43
-
-
0028168643
-
P53-deficient mice are extremely susceptible to radiation-induced tumorigenesis
-
Kemp CJ, Wheldon T, Balmain A (1994): P53-deficient mice are extremely susceptible to radiation-induced tumorigenesis. Nature Genet 8:66-69.
-
(1994)
Nature Genet
, vol.8
, pp. 66-69
-
-
Kemp, C.J.1
Wheldon, T.2
Balmain, A.3
-
44
-
-
0027534837
-
Inherited breast and ovarian cancer. What are the risks? What are the choices?
-
King M-C, Rowell S, Love S (1993): Inherited breast and ovarian cancer. What are the risks? What are the choices? JAMA 269: 1975-1980.
-
(1993)
JAMA
, vol.269
, pp. 1975-1980
-
-
King, M.-C.1
Rowell, S.2
Love, S.3
-
45
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su KL, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D, Finniear R, Markham A, Groffen J, Boguski MS, Altschul SF, Horii A, Ando H, Mioshi Y, Miki Y, Nishisho I, Nakamura Y (1991): Identification of FAP locus genes from chromosome 5q21. Science 253:661-665.
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, K.L.3
Vogelstein, B.4
Bryan, T.M.5
Levy, D.B.6
Smith, K.J.7
Preisinger, A.C.8
Hedge, P.9
McKechnie, D.10
Finniear, R.11
Markham, A.12
Groffen, J.13
Boguski, M.S.14
Altschul, S.F.15
Horii, A.16
Ando, H.17
Mioshi, Y.18
Miki, Y.19
Nishisho, I.20
Nakamura, Y.21
more..
-
46
-
-
0021879645
-
Hereditary cancer, oncogenes and antioncogenes
-
Knudson AG (1985): Hereditary cancer, oncogenes and antioncogenes. Cancer Res 45:1437-1443.
-
(1985)
Cancer Res
, vol.45
, pp. 1437-1443
-
-
Knudson, A.G.1
-
47
-
-
0028585821
-
Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations
-
Kolodner RD, Hall NR, Lipford J, Kane MF, Rao MRS, Morrison P, Wirth L, Finan PJ, Burn J, Chapman P, Earabino C, Merchant E, Bishop DT (1994): Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations. Genomics 24:516-526.
-
(1994)
Genomics
, vol.24
, pp. 516-526
-
-
Kolodner, R.D.1
Hall, N.R.2
Lipford, J.3
Kane, M.F.4
Rao, M.R.S.5
Morrison, P.6
Wirth, L.7
Finan, P.J.8
Burn, J.9
Chapman, P.10
Earabino, C.11
Merchant, E.12
Bishop, D.T.13
-
48
-
-
0025232703
-
Diploid predominance in hereditary nonpolyposis colorectal carcinoma evaluated by flow cytometry
-
Kouri M, Laasonen A, Mecklin J-P, Järvinen H, Franssila K, Pyrhönen S (1990): Diploid predominance in hereditary nonpolyposis colorectal carcinoma evaluated by flow cytometry. Cancer 65:1825-1829.
-
(1990)
Cancer
, vol.65
, pp. 1825-1829
-
-
Kouri, M.1
Laasonen, A.2
Mecklin, J.-P.3
Järvinen, H.4
Franssila, K.5
Pyrhönen, S.6
-
49
-
-
0027205395
-
Slippery DNA and diseases
-
Kunkel TA (1993): Slippery DNA and diseases. Nature 365:207-208.
-
(1993)
Nature
, vol.365
, pp. 207-208
-
-
Kunkel, T.A.1
-
50
-
-
0026951979
-
Natural history of at-risk Lynch syndrome family members with respect to adenomas
-
Lanspa SJ, Jenkins JX, Watson P, Smyrk TC, Cavalieri RJ, Lynch JF, Lynch HT (1992): Natural history of at-risk Lynch syndrome family members with respect to adenomas. Nebr Med J 77:310-313.
-
(1992)
Nebr Med J
, vol.77
, pp. 310-313
-
-
Lanspa, S.J.1
Jenkins, J.X.2
Watson, P.3
Smyrk, T.C.4
Cavalieri, R.J.5
Lynch, J.F.6
Lynch, H.T.7
-
51
-
-
0028572431
-
Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients
-
Lazar V, Grandjouan S, Bognel C, Couturier D, Rougier P, Bellet D, Bressac-de Paillerets B (1994): Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients. Hum Mol Genet 3:2257-2260.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 2257-2260
-
-
Lazar, V.1
Grandjouan, S.2
Bognel, C.3
Couturier, D.4
Rougier, P.5
Bellet, D.6
Bressac-de Paillerets, B.7
-
52
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach FS, Nicolaides NC, Papadopulos N, Liu B, Jen J, Parsons R, Peltomäki P, Sistonen P, Aaltonen LA, Nyström-Lahti M, Guan X-Y, Zhang J, Meltzer PS, Yu J-W, Kao F-T, Chen DJ, Cerosaletti KM, Foumler REK, Todd S, Lewis T, Leach RJ, Naylor SL, Weissenbach J, Mecklin J-P, Järvinen H, Petersen GM, Hamilton SR, Green J, Jass J, Watson P, Lynch HT, Trent JM, de la Chapelle A, Kinzler KW, Vogelstein B (1993): Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75:1216-1225.
-
(1993)
Cell
, vol.75
, pp. 1216-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopulos, N.3
Liu, B.4
Jen, J.5
Parsons, R.6
Peltomäki, P.7
Sistonen, P.8
Aaltonen, L.A.9
Nyström-Lahti, M.10
Guan, X.-Y.11
Zhang, J.12
Meltzer, P.S.13
Yu, J.-W.14
Kao, F.-T.15
Chen, D.J.16
Cerosaletti, K.M.17
Foumler, R.E.K.18
Todd, S.19
Lewis, T.20
Leach, R.J.21
Naylor, S.L.22
Weissenbach, J.23
Mecklin, J.-P.24
Järvinen, H.25
Petersen, G.M.26
Hamilton, S.R.27
Green, J.28
Jass, J.29
Watson, P.30
Lynch, H.T.31
Trent, J.M.32
De La Chapelle, A.33
Kinzler, K.W.34
Vogelstein, B.35
more..
-
53
-
-
0023572211
-
The gene for familial polyposis coli maps to the long arm of chromosome 5
-
Leppert M, Dobbs M, Scambler P, O'Connell P, Nakamura Y, Stauffer D, Woodward S, Burt R, Hughes J, Gardner E, Lathrop M, Wasmuth J, Lalouel J-M, White R (1987): The gene for familial polyposis coli maps to the long arm of chromosome 5. Science 238:1411-1413.
-
(1987)
Science
, vol.238
, pp. 1411-1413
-
-
Leppert, M.1
Dobbs, M.2
Scambler, P.3
O'Connell, P.4
Nakamura, Y.5
Stauffer, D.6
Woodward, S.7
Burt, R.8
Hughes, J.9
Gardner, E.10
Lathrop, M.11
Wasmuth, J.12
Lalouel, J.-M.13
White, R.14
-
54
-
-
0023649836
-
High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12
-
Levinson G, Gutman GA (1987): High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12. Nucleic Acids Res 15:5323-6338.
-
(1987)
Nucleic Acids Res
, vol.15
, pp. 5323-6338
-
-
Levinson, G.1
Gutman, G.A.2
-
55
-
-
0027964920
-
Screening/early detection model for colorectal cancer. Why screen?
-
Lieberman D (1994): Screening/early detection model for colorectal cancer. Why screen? Cancer 74:2023-2027.
-
(1994)
Cancer
, vol.74
, pp. 2023-2027
-
-
Lieberman, D.1
-
56
-
-
0027485551
-
Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer
-
Lindblom A, Tannergard P, Werelius B, Nordenskjold M (1993): Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer. Nature Genet 5:279-282.
-
(1993)
Nature Genet
, vol.5
, pp. 279-282
-
-
Lindblom, A.1
Tannergard, P.2
Werelius, B.3
Nordenskjold, M.4
-
57
-
-
0028106776
-
hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds
-
Liu B, Parson RE, Hamilton SR, Petersen GM, Lynch HT, Watson P, Markowitz S, Willson JKV, Green J, de la Chapelle A, Kinzler KW, Vogelstein B (1994): hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds. Cancer Res 54:4590-4594.
-
(1994)
Cancer Res
, vol.54
, pp. 4590-4594
-
-
Liu, B.1
Parson, R.E.2
Hamilton, S.R.3
Petersen, G.M.4
Lynch, H.T.5
Watson, P.6
Markowitz, S.7
Willson, J.K.V.8
Green, J.9
De La Chapelle, A.10
Kinzler, K.W.11
Vogelstein, B.12
-
58
-
-
0028859671
-
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
-
Liu B, Nicolaides NC, Markowitz S, Willson JKV, Parsons RE, Jen J, Papadopolous N, Peltomaki P, de la Chapelle A, Hamilton SR, Kinzler KW, Vogelstein B (1995): Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nature Genet 9:48-55.
-
(1995)
Nature Genet
, vol.9
, pp. 48-55
-
-
Liu, B.1
Nicolaides, N.C.2
Markowitz, S.3
Willson, J.K.V.4
Parsons, R.E.5
Jen, J.6
Papadopolous, N.7
Peltomaki, P.8
De La Chapelle, A.9
Hamilton, S.R.10
Kinzler, K.W.11
Vogelstein, B.12
-
59
-
-
0028915223
-
Genetic instability in the majority of young patients with colorectal cancer
-
Liu B, Farrington SM, Petersen GM, Hamilton SR, Parsons R, Papadoppulos N, Fujiwara T, Jen J, Kinzler KW, Wyllie AH, Vogelstein B, Dunlop MG (1995): Genetic instability in the majority of young patients with colorectal cancer. Nature Med 1:348-352.
-
(1995)
Nature Med
, vol.1
, pp. 348-352
-
-
Liu, B.1
Farrington, S.M.2
Petersen, G.M.3
Hamilton, S.R.4
Parsons, R.5
Papadoppulos, N.6
Fujiwara, T.7
Jen, J.8
Kinzler, K.W.9
Wyllie, A.H.10
Vogelstein, B.11
Dunlop, M.G.12
-
60
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
Loeb LA (1991): Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51:3075-3079.
-
(1991)
Cancer Res
, vol.51
, pp. 3075-3079
-
-
Loeb, L.A.1
-
61
-
-
0028019398
-
Microsatellite instability: Marker of a mutator phenotype in cancer
-
Loeb LA (1994): Microsatellite instability: Marker of a mutator phenotype in cancer. Cancer Res 54:5059-5063.
-
(1994)
Cancer Res
, vol.54
, pp. 5059-5063
-
-
Loeb, L.A.1
-
62
-
-
0028031046
-
Distinct RB1 gene mutations with low penetrance in hereditary retinoblastoma
-
Lohmann DR, Brandt B, Hopping W, Passarge E, Horsthemke B (1994): Distinct RB1 gene mutations with low penetrance in hereditary retinoblastoma. Hum Genet 94:349-354.
-
(1994)
Hum Genet
, vol.94
, pp. 349-354
-
-
Lohmann, D.R.1
Brandt, B.2
Hopping, W.3
Passarge, E.4
Horsthemke, B.5
-
63
-
-
2842525658
-
Biological characterizaton of hereditary nonpolyposis colorectal cancer: I. Nuclear ploidy, AgNOR count, microvessel distribution, oncogene expression, and grade-related parameters
-
in press
-
Losi L, Fante R, Di Gregorio C, Aisoni ML, Lanza G, Maestri I, Roncucci L, Pedroni M, Ponz de Leon M (1996): Biological characterizaton of hereditary nonpolyposis colorectal cancer: I. Nuclear ploidy, AgNOR count, microvessel distribution, oncogene expression, and grade-related parameters. Am J Clin Pathol (in press).
-
(1996)
Am J Clin Pathol
-
-
Losi, L.1
Fante, R.2
Di Gregorio, C.3
Aisoni, M.L.4
Lanza, G.5
Maestri, I.6
Roncucci, L.7
Pedroni, M.8
Ponz De Leon, M.9
-
64
-
-
0022622759
-
Frequency of hereditary nonpolyposis colorectal cancer
-
Lynch HT (1986): Frequency of hereditary nonpolyposis colorectal cancer. Gastroenterology 90:486-489.
-
(1986)
Gastroenterology
, vol.90
, pp. 486-489
-
-
Lynch, H.T.1
-
65
-
-
0014137031
-
Heredity and adenocarcinoma of the colon
-
Lynch HT, Krush AJ (1967): Heredity and adenocarcinoma of the colon. Gastroenterology 53:517-527.
-
(1967)
Gastroenterology
, vol.53
, pp. 517-527
-
-
Lynch, H.T.1
Krush, A.J.2
-
66
-
-
0015077284
-
Cancer family G revisited: 1895-1970
-
Lynch HT, Krush AJ (1971): Cancer family G revisited: 1895-1970. Cancer 27:1505-1511.
-
(1971)
Cancer
, vol.27
, pp. 1505-1511
-
-
Lynch, H.T.1
Krush, A.J.2
-
67
-
-
0021952377
-
Hereditary non polyposis colorectal cancer in a Navajo Indian family
-
Lynch HT, Drouhard TJ, Schuelke GS, Biscone KA, Lynch JF, Danes BS (1985): Hereditary non polyposis colorectal cancer in a Navajo Indian family. Cancer Genet Cytogenet 15:209-213.
-
(1985)
Cancer Genet Cytogenet
, vol.15
, pp. 209-213
-
-
Lynch, H.T.1
Drouhard, T.J.2
Schuelke, G.S.3
Biscone, K.A.4
Lynch, J.F.5
Danes, B.S.6
-
68
-
-
0022006650
-
Muir-Torre syndrome in several members of a family with a variant of the cancer family syndrome
-
Lynch HT, Fusaro RM, Roberts L, Voorhees GJ, Lynch JF (1985): Muir-Torre syndrome in several members of a family with a variant of the cancer family syndrome. Br J Dermatol 113:295-301.
-
(1985)
Br J Dermatol
, vol.113
, pp. 295-301
-
-
Lynch, H.T.1
Fusaro, R.M.2
Roberts, L.3
Voorhees, G.J.4
Lynch, J.F.5
-
69
-
-
0025915010
-
Hereditary nonpolyposis colorectal cancer: Genetics, pathology, natural history, and cancer control
-
Lynch HT, Lanspa S, Smyrk T, Boman B, Watson P, Lynch J (1991): Hereditary nonpolyposis colorectal cancer: Genetics, pathology, natural history, and cancer control. Cancer Genet Cytogenet 53:143-160.
-
(1991)
Cancer Genet Cytogenet
, vol.53
, pp. 143-160
-
-
Lynch, H.T.1
Lanspa, S.2
Smyrk, T.3
Boman, B.4
Watson, P.5
Lynch, J.6
-
70
-
-
0025911780
-
Hereditary colorectal cancer
-
Lynch HT, Smyrk T, Watson P, Lanspa SJ, Boman BM, Lynch PM, Lynch JF, Cavalieri J (1991): Hereditary colorectal cancer. Semin Oncol 18:337-366.
-
(1991)
Semin Oncol
, vol.18
, pp. 337-366
-
-
Lynch, H.T.1
Smyrk, T.2
Watson, P.3
Lanspa, S.J.4
Boman, B.M.5
Lynch, P.M.6
Lynch, J.F.7
Cavalieri, J.8
-
71
-
-
0027248156
-
Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review
-
Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, Cavalieri RJ, Boland CR (1993): Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review. Gastroenterology 104:1535-1549.
-
(1993)
Gastroenterology
, vol.104
, pp. 1535-1549
-
-
Lynch, H.T.1
Smyrk, T.C.2
Watson, P.3
Lanspa, S.J.4
Lynch, J.F.5
Lynch, P.M.6
Cavalieri, R.J.7
Boland, C.R.8
-
72
-
-
0028362290
-
Hereditary nonpolyposis colorectal carcinoma (HNPCC): Clinical application of molecular diagnostic testing
-
Lynch PM (1994): Hereditary nonpolyposis colorectal carcinoma (HNPCC): Clinical application of molecular diagnostic testing. Ann Med 26:221-228.
-
(1994)
Ann Med
, vol.26
, pp. 221-228
-
-
Lynch, P.M.1
-
73
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin D, Li FP, Strong LC, Fraumeni JF Jr, Nelson CE, Kim DH, Kassel J, Gryka MA, Bischoff FZ, Tainsky MA, Friend SH (1990): Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni Jr., J.F.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
Friend, S.H.11
-
74
-
-
0029066689
-
Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
-
Markowitz S, Wang J, Myeroff L, Parsons R, Sun LZ, Lutterbaugh J, Fan RS, Zborowska E, Kinzler KW, Vogelstein B, Brattain M, Willson JKW (1995): Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 268:1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
Parsons, R.4
Sun, L.Z.5
Lutterbaugh, J.6
Fan, R.S.7
Zborowska, E.8
Kinzler, K.W.9
Vogelstein, B.10
Brattain, M.11
Willson, J.K.W.12
-
75
-
-
0018844274
-
Patterns of gastrointestinal cancer in European migrants to Australia: The role of dietary changes
-
McMichael AJ, McCall MG, Hartshorne JM, Woodings TL (1980): Patterns of gastrointestinal cancer in European migrants to Australia: The role of dietary changes. Int J Cancer 25:431-437.
-
(1980)
Int J Cancer
, vol.25
, pp. 431-437
-
-
McMichael, A.J.1
McCall, M.G.2
Hartshorne, J.M.3
Woodings, T.L.4
-
76
-
-
0023513650
-
Frequency of hereditary colorectal carcinoma
-
Mecklin J-P (1987): Frequency of hereditary colorectal carcinoma. Gastroenterology 93:1021-1025.
-
(1987)
Gastroenterology
, vol.93
, pp. 1021-1025
-
-
Mecklin, J.-P.1
-
77
-
-
0022648252
-
Clinical features of colorectal carcinoma in cancer family syndrome
-
Mecklin J-P, Jarvinen HJ (1986): Clinical features of colorectal carcinoma in cancer family syndrome. Dis Colon Rectum 29:160-164.
-
(1986)
Dis Colon Rectum
, vol.29
, pp. 160-164
-
-
Mecklin, J.-P.1
Jarvinen, H.J.2
-
78
-
-
0026088343
-
Tumor spectrum in cancer family syndrome
-
Mecklin J-P, Järvinen HJ (1991): Tumor spectrum in cancer family syndrome. Cancer 68:1109-1112.
-
(1991)
Cancer
, vol.68
, pp. 1109-1112
-
-
Mecklin, J.-P.1
Järvinen, H.J.2
-
80
-
-
0022619767
-
Cancer family syndrome: Genetic analysis of 22 Finnish kindreds
-
Mecklin J-P, Järvinen HJ, Peltokallio P (1986): Cancer family syndrome: Genetic analysis of 22 Finnish kindreds. Gastroenterology 90:328-333.
-
(1986)
Gastroenterology
, vol.90
, pp. 328-333
-
-
Mecklin, J.-P.1
Järvinen, H.J.2
Peltokallio, P.3
-
82
-
-
0028230597
-
Frequent microsatellite instability in primary small cell lung cancer
-
Merlo A, Mabry M, Gabrielson E, Vollmer R, Baylin SB, Sidransky D (1994): Frequent microsatellite instability in primary small cell lung cancer. Cancer Res 54:2098-2101.
-
(1994)
Cancer Res
, vol.54
, pp. 2098-2101
-
-
Merlo, A.1
Mabry, M.2
Gabrielson, E.3
Vollmer, R.4
Baylin, S.B.5
Sidransky, D.6
-
83
-
-
0019183253
-
On the nature of susceptibility to cancer
-
Miller DG (1980): On the nature of susceptibility to cancer. Cancer 46:1307-1318.
-
(1980)
Cancer
, vol.46
, pp. 1307-1318
-
-
Miller, D.G.1
-
85
-
-
0026355962
-
Mechanisms and biological effects of mismatch repair
-
Modrich P (1991): Mechanisms and biological effects of mismatch repair. Annu Rev Genet 25:229-253.
-
(1991)
Annu Rev Genet
, vol.25
, pp. 229-253
-
-
Modrich, P.1
-
86
-
-
0028564949
-
Mismatch repair, genetic stability, and cancer
-
Modrich P (1994): Mismatch repair, genetic stability, and cancer. Science 266:1959-1960.
-
(1994)
Science
, vol.266
, pp. 1959-1960
-
-
Modrich, P.1
-
88
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
-
Nicolaides NC, Papadopoulos N, Liu B, Wei Y-F, Carter CK, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, Venter JC, Dunlop MG, Hamilton SR, Petersen MG, de la Chapelle A, Vogelstein B, Kinzler KW (1994): Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 371:75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
Wei, Y.-F.4
Carter, C.K.5
Ruben, S.M.6
Rosen, C.A.7
Haseltine, W.A.8
Fleischmann, R.D.9
Fraser, C.M.10
Adams, M.D.11
Venter, J.C.12
Dunlop, M.G.13
Hamilton, S.R.14
Petersen, M.G.15
De La Chapelle, A.16
Vogelstein, B.17
Kinzler, K.W.18
-
89
-
-
0028108802
-
Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage
-
Nyström-Lahti M, Parsons R, Sistonen P, Pylkkänen L, Aaltonen LA, Leach FS, Hamilton SR, Watson P, Bronson E, Fusaro R, Cavalieri J, Lynch J, Lanspa S, Smyrk T, Lynch P, Drouhard T, Kinzler KW, Vogelstein B, Lynch HT, de la Chapelle A, Peltomäki P (1994): Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage. Am J Hum Genet 55:659-665.
-
(1994)
Am J Hum Genet
, vol.55
, pp. 659-665
-
-
Nyström-Lahti, M.1
Parsons, R.2
Sistonen, P.3
Pylkkänen, L.4
Aaltonen, L.A.5
Leach, F.S.6
Hamilton, S.R.7
Watson, P.8
Bronson, E.9
Fusaro, R.10
Cavalieri, J.11
Lynch, J.12
Lanspa, S.13
Smyrk, T.14
Lynch, P.15
Drouhard, T.16
Kinzler, K.W.17
Vogelstein, B.18
Lynch, H.T.19
De La Chapelle, A.20
Peltomäki, P.21
more..
-
90
-
-
0028283368
-
Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families
-
Nyström-Lahti M, Sistonen P, Mecklin J-P, Pylkkänen L, Aaltonen LA, Järvinen H, Weissenbach J, de la Chapelle A, Peltomäki P (1994): Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families. Proc Natl Acad Sci USA 91:6054-6058.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6054-6058
-
-
Nyström-Lahti, M.1
Sistonen, P.2
Mecklin, J.-P.3
Pylkkänen, L.4
Aaltonen, L.A.5
Järvinen, H.6
Weissenbach, J.7
De La Chapelle, A.8
Peltomäki, P.9
-
91
-
-
0029008683
-
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells
-
Palombo F, Gallinari P, Iaccarino I, Lettieri T, Hughes M, D'Arrigo A, Truong O, Hsuan JJ, Jiricny J (1995): GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science 268:1912-1914.
-
(1995)
Science
, vol.268
, pp. 1912-1914
-
-
Palombo, F.1
Gallinari, P.2
Iaccarino, I.3
Lettieri, T.4
Hughes, M.5
D'Arrigo, A.6
Truong, O.7
Hsuan, J.J.8
Jiricny, J.9
-
92
-
-
0028350601
-
Mutation of mutL homolog in hereditary colon cancer
-
Papadopoulos N, Nicolaides NC, Wei Y-F, Ruben SM, Carter KC, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, Venter JC, Hamilton SR, Petersen GM, Watson P, Lynch HT, Peltomäki P, Mecklin J-P, de la Chapelle A, Kinzler KW, Vogelstein B (1994): Mutation of mutL homolog in hereditary colon cancer. Science 263:1625-1629.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Wei, Y.-F.3
Ruben, S.M.4
Carter, K.C.5
Rosen, C.A.6
Haseltine, W.A.7
Fleischmann, R.D.8
Fraser, C.M.9
Adams, M.D.10
Venter, J.C.11
Hamilton, S.R.12
Petersen, G.M.13
Watson, P.14
Lynch, H.T.15
Peltomäki, P.16
Mecklin, J.-P.17
De La Chapelle, A.18
Kinzler, K.W.19
Vogelstein, B.20
more..
-
93
-
-
0029069972
-
Mutations of GTBP in genetically unstable cells
-
Papadopoulos N, Nicolaides N, Liu B, Parsons R, Lengauer C, Palombo F, D'Arrigo A, Markowitz S, Willson JKV, Kinzler KW, Jiricny J, Vogelstein B (1995): Mutations of GTBP in genetically unstable cells. Science 268:1915-1917.
-
(1995)
Science
, vol.268
, pp. 1915-1917
-
-
Papadopoulos, N.1
Nicolaides, N.2
Liu, B.3
Parsons, R.4
Lengauer, C.5
Palombo, F.6
D'Arrigo, A.7
Markowitz, S.8
Willson, J.K.V.9
Kinzler, K.W.10
Jiricny, J.11
Vogelstein, B.12
-
94
-
-
0027137935
-
+ tumor cells
-
+ tumor cells. Cell 75:1227-1236.
-
(1993)
Cell
, vol.75
, pp. 1227-1236
-
-
Parsons, R.1
Li, G.-M.2
Longley, M.J.3
Fang, W.-H.4
Papadopoulos, N.5
Jen, J.6
De La Chapelle, A.7
Kinzler, K.W.8
Vogelstein, B.9
Modrich, P.10
-
95
-
-
0029061638
-
Mismatch repair deficiency in phenotypically normal human cells
-
Parsons R, Li G-M, Longley M, Modrich P, Liu B, Berk T, Hamilton SR, Kinzler KW, Vogelstein B (1995): Mismatch repair deficiency in phenotypically normal human cells. Science 268:738-740.
-
(1995)
Science
, vol.268
, pp. 738-740
-
-
Parsons, R.1
Li, G.-M.2
Longley, M.3
Modrich, P.4
Liu, B.5
Berk, T.6
Hamilton, S.R.7
Kinzler, K.W.8
Vogelstein, B.9
-
96
-
-
0027263363
-
Genetic mapping of a locus predisposing to human colorectal cancer
-
Peltomäki P, Aaltonen LA, Sistonen P, Pylkkänen L, Mecklin J-P, Järvinen H, Green JS, Jass JR, Weber JL, Leach FS, Petersen GM, Hamilton SR, de la Chapelle A, Vogelstein B (1993): Genetic mapping of a locus predisposing to human colorectal cancer. Science 260:810-812.
-
(1993)
Science
, vol.260
, pp. 810-812
-
-
Peltomäki, P.1
Aaltonen, L.A.2
Sistonen, P.3
Pylkkänen, L.4
Mecklin, J.-P.5
Järvinen, H.6
Green, J.S.7
Jass, J.R.8
Weber, J.L.9
Leach, F.S.10
Petersen, G.M.11
Hamilton, S.R.12
De La Chapelle, A.13
Vogelstein, B.14
-
97
-
-
0028283423
-
Genetic basis of hereditary nonpolyposis colorectal carcinoma (HNPCC)
-
Peltomäki PT (1994): Genetic basis of hereditary nonpolyposis colorectal carcinoma (HNPCC). Ann Med 26:215-219.
-
(1994)
Ann Med
, vol.26
, pp. 215-219
-
-
Peltomäki, P.T.1
-
98
-
-
0024299571
-
Gene losses in human tumours
-
Ponder B (1988): Gene losses in human tumours. Nature 335: 400-402.
-
(1988)
Nature
, vol.335
, pp. 400-402
-
-
Ponder, B.1
-
99
-
-
0028290753
-
Prevalence of hereditary nonpolyposis colorectal cancer (HNPCC)
-
Ponz de Leon M (1994): Prevalence of hereditary nonpolyposis colorectal cancer (HNPCC). Ann Med 26:209-214.
-
(1994)
Ann Med
, vol.26
, pp. 209-214
-
-
Ponz De Leon, M.1
-
100
-
-
0023471287
-
Incidence and familial occurrence of colorectal cancer and polyps in a health-care district of northern Italy
-
Ponz de Leon M, Antonioli A, Ascari A, Zanghieri G, Sacchetti C (1987): Incidence and familial occurrence of colorectal cancer and polyps in a health-care district of northern Italy. Cancer 60: 2848-2859.
-
(1987)
Cancer
, vol.60
, pp. 2848-2859
-
-
Ponz De Leon, M.1
Antonioli, A.2
Ascari, A.3
Zanghieri, G.4
Sacchetti, C.5
-
101
-
-
0026766948
-
Genetic transmission of colorectal cancer: Exploratory data analysis from a population-based registry
-
Ponz de Leon M, Scapoli C, Zanghieri G, Sassatelli R, Sacchetti C, Barrai I (1992): Genetic transmission of colorectal cancer: Exploratory data analysis from a population-based registry. J Med Genet 29:531-538.
-
(1992)
J Med Genet
, vol.29
, pp. 531-538
-
-
Ponz De Leon, M.1
Scapoli, C.2
Zanghieri, G.3
Sassatelli, R.4
Sacchetti, C.5
Barrai, I.6
-
102
-
-
0027360660
-
Risk of cancer in the follow-up of families with HNPCC
-
Ponz de Leon M, Benatti P, Pedroni M, Sassatelli R, Roncucci L (1993): Risk of cancer in the follow-up of families with HNPCC. Int J Cancer 55:202-207.
-
(1993)
Int J Cancer
, vol.55
, pp. 202-207
-
-
Ponz De Leon, M.1
Benatti, P.2
Pedroni, M.3
Sassatelli, R.4
Roncucci, L.5
-
103
-
-
0027177167
-
Identification of hereditary nonpolyposis colorectal cancer in the general population
-
Ponz de Leon M, Sassatelli R, Benatti P, Roncucci L (1993): Identification of hereditary nonpolyposis colorectal cancer in the general population. Cancer 71:3493-3501.
-
(1993)
Cancer
, vol.71
, pp. 3493-3501
-
-
Ponz De Leon, M.1
Sassatelli, R.2
Benatti, P.3
Roncucci, L.4
-
104
-
-
0028052186
-
Age of onset in familial adenomatous polyposis: Heterogeneity within families and among APC mutations
-
Presciuttini S, Varesco L, Sala P, Gismondi V, Rossetti C, Bafico A, Ferrara GB, Bertario L (1994): Age of onset in familial adenomatous polyposis: Heterogeneity within families and among APC mutations. Ann Hum Genet 8:331-342.
-
(1994)
Ann Hum Genet
, vol.8
, pp. 331-342
-
-
Presciuttini, S.1
Varesco, L.2
Sala, P.3
Gismondi, V.4
Rossetti, C.5
Bafico, A.6
Ferrara, G.B.7
Bertario, L.8
-
105
-
-
0026587603
-
Constitutional p53 mutation in a non-Li-Fraumeni cancer family
-
Prosser J, Porter D, Coles C, Condie A, Thompson AM, Chetty U, Steel CM, Evans HJ (1992): Constitutional p53 mutation in a non-Li-Fraumeni cancer family. Br J Cancer 65:527-528.
-
(1992)
Br J Cancer
, vol.65
, pp. 527-528
-
-
Prosser, J.1
Porter, D.2
Coles, C.3
Condie, A.4
Thompson, A.M.5
Chetty, U.6
Steel, C.M.7
Evans, H.J.8
-
106
-
-
0028609451
-
Identification of a microsatellite instability phenotype in meningiomas
-
Pykett MJ, Murphy M, Harnish PR, George DL (1994): Identification of a microsatellite instability phenotype in meningiomas. Cancer Res 54:6340-6343.
-
(1994)
Cancer Res
, vol.54
, pp. 6340-6343
-
-
Pykett, M.J.1
Murphy, M.2
Harnish, P.R.3
George, D.L.4
-
107
-
-
12044249110
-
Microsatellite instability occurs frequently in human gastric carcinoma
-
Rhyu M-G, Park W-S, Meltzer SJ (1994): Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene 9:29-32.
-
(1994)
Oncogene
, vol.9
, pp. 29-32
-
-
Rhyu, M.-G.1
Park, W.-S.2
Meltzer, S.J.3
-
108
-
-
0025145277
-
5-methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes
-
Rideout WM, Coetzee GA, Olumi AF, Jones PA (1990): 5-methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249:1288-1290.
-
(1990)
Science
, vol.249
, pp. 1288-1290
-
-
Rideout, W.M.1
Coetzee, G.A.2
Olumi, A.F.3
Jones, P.A.4
-
109
-
-
0027366916
-
Genetic instability of microsatellites in endometrial carcinoma
-
Risinger JI, Berchuck A, Kohler MF, Watson P, Lynch HT, Boyd J (1993): Genetic instability of microsatellites in endometrial carcinoma. Cancer Res 53:5100-5103.
-
(1993)
Cancer Res
, vol.53
, pp. 5100-5103
-
-
Risinger, J.I.1
Berchuck, A.2
Kohler, M.F.3
Watson, P.4
Lynch, H.T.5
Boyd, J.6
-
110
-
-
0008349760
-
Hereditary nonpolyposis colorectal cancer: An awareness
-
San Jose BA, Navarro NS, Doble F (1989): Hereditary nonpolyposis colorectal cancer: An awareness. JMMS 25:37-38.
-
(1989)
JMMS
, vol.25
, pp. 37-38
-
-
San Jose, B.A.1
Navarro, N.S.2
Doble, F.3
-
111
-
-
0027973823
-
Genetic epidemiology of hereditary non-polyposis colorectal cancer syndromes in Modena, Italy: Results of a complex segregation analysis
-
Scapoli C, Ponz de Leon M, Sassatelli R, Benatti P, Roncucci L, Collins A, Morton NE, Barrai I (1994): Genetic epidemiology of hereditary non-polyposis colorectal cancer syndromes in Modena, Italy: Results of a complex segregation analysis. Ann Hum Genet 58:275-295.
-
(1994)
Ann Hum Genet
, vol.58
, pp. 275-295
-
-
Scapoli, C.1
Ponz De Leon, M.2
Sassatelli, R.3
Benatti, P.4
Roncucci, L.5
Collins, A.6
Morton, N.E.7
Barrai, I.8
-
112
-
-
0024437947
-
The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors
-
Schaaper RM, Radman M (1989): The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors. EMBO J 8:3511-3516.
-
(1989)
EMBO J
, vol.8
, pp. 3511-3516
-
-
Schaaper, R.M.1
Radman, M.2
-
113
-
-
0027410999
-
Molecular biology of colorectal neoplasia
-
Scott N, Quirke P (1993): Molecular biology of colorectal neoplasia. Gut 34:289-292.
-
(1993)
Gut
, vol.34
, pp. 289-292
-
-
Scott, N.1
Quirke, P.2
-
114
-
-
0028362325
-
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
-
Shibata D, Peinado MA, Ionov Y, Malkhosyan S, Perucho M (1994): Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nat Genet 6:273-281.
-
(1994)
Nat Genet
, vol.6
, pp. 273-281
-
-
Shibata, D.1
Peinado, M.A.2
Ionov, Y.3
Malkhosyan, S.4
Perucho, M.5
-
115
-
-
0028284887
-
Genetic instability of microsatellite sequences in many non-small cell lung carcinomas
-
Shridhar V, Siegfried J, Hunt J, del Mar Alonso M, Smith DI (1994): Genetic instability of microsatellite sequences in many non-small cell lung carcinomas. Cancer Res 54:2084-2087.
-
(1994)
Cancer Res
, vol.54
, pp. 2084-2087
-
-
Shridhar, V.1
Siegfried, J.2
Hunt, J.3
Del Mar Alonso, M.4
Smith, D.I.5
-
116
-
-
0028073532
-
Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21
-
Steichen-Gersdorf E, Gallion HH, Ford D, Girodet C, Easton DF, DiCioccio R, Evans G, Ponder MA, Pye C, Mazoyer S, Noguchi T, Karengueven F, Sobol H, Hardouin A, Bignon Y-J, Piver S, Smith SA, Ponder BAJ (1994): Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21. Am J Hum Genet 55:870-875.
-
(1994)
Am J Hum Genet
, vol.55
, pp. 870-875
-
-
Steichen-Gersdorf, E.1
Gallion, H.H.2
Ford, D.3
Girodet, C.4
Easton, D.F.5
DiCioccio, R.6
Evans, G.7
Ponder, M.A.8
Pye, C.9
Mazoyer, S.10
Noguchi, T.11
Karengueven, F.12
Sobol, H.13
Hardouin, A.14
Bignon, Y.-J.15
Piver, S.16
Smith, S.A.17
Ponder, B.A.J.18
-
117
-
-
0027306173
-
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
-
Strand M, Prolla TA, Liskay RM, Petes TD (1993): Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365:274-276.
-
(1993)
Nature
, vol.365
, pp. 274-276
-
-
Strand, M.1
Prolla, T.A.2
Liskay, R.M.3
Petes, T.D.4
-
118
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau SN, Bren G, Schaid D (1993): Microsatellite instability in cancer of the proximal colon. Science 260:816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
119
-
-
0028301255
-
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability
-
Umar A, Boyer JC, Thomas DC, Nguyen DC, Risinger JI, Boyd J, Ionov Y, Perucho M, Kunkel TA (1994): Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J Biol Chem 269:14367-14370.
-
(1994)
J Biol Chem
, vol.269
, pp. 14367-14370
-
-
Umar, A.1
Boyer, J.C.2
Thomas, D.C.3
Nguyen, D.C.4
Risinger, J.I.5
Boyd, J.6
Ionov, Y.7
Perucho, M.8
Kunkel, T.A.9
-
120
-
-
0024518241
-
Screening for hereditary nonpolyposis colorectal cancer: A study of 22 kindreds in the Netherlands
-
Vasen HFA, den Hartog Jager FC, Menko FH, Nagengast FM (1989): Screening for hereditary nonpolyposis colorectal cancer: A study of 22 kindreds in the Netherlands. Am J Med 86:278-281.
-
(1989)
Am J Med
, vol.86
, pp. 278-281
-
-
Vasen, H.F.A.1
Den Hartog Jager, F.C.2
Menko, F.H.3
Nagengast, F.M.4
-
121
-
-
0025326851
-
The tumour spectrum in hereditary nonpolyposis colorectal cancer: A study of 24 kindreds in the Netherlands
-
Vasen HFA, Offerhaus GJ, den Hartog Jager FC, Menko FH, Nagengast FM, Griffioen G, van Hogezand RB, Heintz AP (1990): The tumour spectrum in hereditary nonpolyposis colorectal cancer: A study of 24 kindreds in the Netherlands. Int J Cancer 46:31-34.
-
(1990)
Int J Cancer
, vol.46
, pp. 31-34
-
-
Vasen, H.F.A.1
Offerhaus, G.J.2
Den Hartog Jager, F.C.3
Menko, F.H.4
Nagengast, F.M.5
Griffioen, G.6
Van Hogezand, R.B.7
Heintz, A.P.8
-
122
-
-
0025848680
-
The International Collaborative Study Group on Hereditary Nonpolyposis Colorectal Cancer
-
Vasen HFA, Mecklin J-P, Meera Khan P, Lynch HT (1991): The International Collaborative Study Group on Hereditary Nonpolyposis Colorectal Cancer. Dis Colon Rectum 34:424-425.
-
(1991)
Dis Colon Rectum
, vol.34
, pp. 424-425
-
-
Vasen, H.F.A.1
Mecklin, J.-P.2
Meera Khan, P.3
Lynch, H.T.4
-
124
-
-
0023748414
-
Genetic alterations during colorectal tumor development
-
Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smiths AKM, Bos JL (1988): Genetic alterations during colorectal tumor development. N Engl J Med 319:525-532.
-
(1988)
N Engl J Med
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
Nakamura, Y.7
White, R.8
Smiths, A.K.M.9
Bos, J.L.10
-
125
-
-
74549208765
-
Heredity with reference to carcinoma
-
Warthin AS (1913): Heredity with reference to carcinoma. Arch Intern Med 12:546-555.
-
(1913)
Arch Intern Med
, vol.12
, pp. 546-555
-
-
Warthin, A.S.1
-
126
-
-
0027467494
-
Extracolonic cancer in hereditary nonpolyposis colorectal cancer
-
Watson P, Lynch HT (1993): Extracolonic cancer in hereditary nonpolyposis colorectal cancer. Cancer 71:677-685.
-
(1993)
Cancer
, vol.71
, pp. 677-685
-
-
Watson, P.1
Lynch, H.T.2
-
128
-
-
0028362315
-
Instability of short tandem repeats (microsatellites) in human cancers
-
Wooster R, Cleton-Jansen A-M, Collins N, Mangion J, Cornelis RS, Cooper CS, Gusterson BA, Ponder BAJ, von Deimling A, Wiestler OD, Cornelisse CJ, Devilee P, Stratton MR (1994): Instability of short tandem repeats (microsatellites) in human cancers. Nat Genet 6:152-156.
-
(1994)
Nat Genet
, vol.6
, pp. 152-156
-
-
Wooster, R.1
Cleton-Jansen, A.-M.2
Collins, N.3
Mangion, J.4
Cornelis, R.S.5
Cooper, C.S.6
Gusterson, B.A.7
Ponder, B.A.J.8
Von Deimling, A.9
Wiestler, O.D.10
Cornelisse, C.J.11
Devilee, P.12
Stratton, M.R.13
-
129
-
-
0028269679
-
Microsatellite instability and loss of heterozygosity in breast cancer
-
Yee CJ, Roodi N, Verrier CS, Pari FF (1994): Microsatellite instability and loss of heterozygosity in breast cancer. Cancer Res 54:1641-1644.
-
(1994)
Cancer Res
, vol.54
, pp. 1641-1644
-
-
Yee, C.J.1
Roodi, N.2
Verrier, C.S.3
Pari, F.F.4
|