Multiple roles for DNA methylation in gametic imprinting

Current Opinion in Genetics and Development

Volumn 6, Issue 2, 1996, Pages 159-163

  Neumann, Bjorn ^a,b   Barlow, Denise P ^a,c  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^b CCIP/EAP 6   (France)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA METHYLTRANSFERASE;

DNA METHYLATION; GAMETE; GENOME IMPRINTING; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0029985241     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(96)80045-1     Document Type: Article

References (45)

1. Eden S, Cedar H: Role of DNA methylation in the regulation of transcription. Curr Opin Genet Dev 1994, 4:255-259.
2. Razin A, Shemer R: DNA methylation in early development. Hum Mol Genet 1995, 4:1751-1755.
3. Clark J, Harrison J, Frommer M: CpG methylation in mammals. Nature Genet 1995, 10:20-27.
4. Bestor TH, Verdine GL: DNA methyltransferases. Curr Opin Cell Biol 1994, 6:380-398.
5. Solter D: Differential imprinting and expression of maternal and paternal genomes. Annu Rev Genet 1988, 22:127-146.
6. Efstratiadis A: Parental imprinting of autosomal mammalian genes. Curr Opin Genet Dev 1994, 4:265-280.
7. Surani MA: Genomic imprinting: control of gene expression by epigenetic inheritance. Curr Opin Cell Biol 1994, 6:390-395.
8. Monk M, Surani MA (Ed) Genomic Imprinting. Development 1990, (Supplement).
9. Barlow DP: Gametic Imprinting in mammals. Science 1995, 270:1610-1613.
10. Mandel J-L: A question of expansion. Nature Genet 1993, 4:8-9.
11. Haas O: Are ABL and BCR imprinted? No definitive answers, but more questions. Leukaemia 1995, 9:740-743.
12. Chaillet JR, Bader DS, Leder P: Regulation of genomic imprinting by gametic and embryonic processes. Genes Dev 1995, 9:1177-1187.
13. iapy) is correlated with methylation status and is influenced by parental lineage. Genes Dev 1994, 8:1463-1472.
14. Rubin CM, Vandevoort CA, Teplitz RL, Schmid CW: Alu repeated DNAs are differentially methylated in primate germ cells. Nucleic Acids Res 1994, 22:5121-5127.
15. Tayahashi Y, Mitani K, Kuwabara K, Hayashi T, Niwa M, Miyashita N, Moriwaki K, Kominami R: Methylation imprinting was observed of mouse mo-2 macrosatellite on the pseudoautosomal region but not on chromosome 9. Chromosoma 1994, 103:450-458.
16. Kawame H, Gartler SM, Hansen RS: Allele specific replication timing in imprinted domains; absence of asynchrony at several loci. Hum Mol Genet 1995, 4:2287-2291. A demonstration that the allelic asynchrony previously identified by flourescence in situ hybridization methods is not always attributable to replication asynchrony but may represent allelic differences in accessibility or segregation.
17. Paldi A, Gyapay G, Jami J: Sex specific recombination rates of imprinted DNA. Curr Biol 1995, 5:1030-1034. Imprinted genes lie in chromosomal regions that show a parental bias in recombination frequency. This had been previously suggested to explain male/female differences in meiotic recombination frequency.
18. Li E, Beard C, Jaenisch R: Role for DNA methylation in genomic imprinting. Nature 1993, 366:362-365.
19. Reik W, Allen ND: Imprinting with or without methylation. Curr Biol 1994, 4:145-147.
20. Beard C, Li E, Jaenisch R: Loss of methylation activates Xist in somatic cells but not in embryonic cells. Genes Dev 1995, 9:2325-2334. Allelic repression of Xist is methylation-dependent, increasing the number of imprinted genes which depend on methylation for allele-specific expression to a total of four.
21. •].
22. Zuccotti M, Monk M: Methylation of the mouse Xist gene in sperm and eggs correlates with imprinted. Xist expression and paternal X inactivation. Nature Genet 1995, 9:316-320. Xist is shown to inherit a methylation imprint from the female gamete which is preserved in the preimplantation embryo, and which could act as the gametic imprinting signal to identify parental alleles.
23. Tremblay KD, Saam JR, Ingram RS, Tilghman SM, Bartolomei MS: A paternal specific methylation imprint marks the alleles of the mouse H19 gene. Nature Genet 1995, 9:407-413. Demonstration that H19 inherits a methylation imprint from the paternal gamete which is preserved in the preimplantation embryo. This is the only example of a paternally inherited putative signalling molecule.
24. Razin A, Kafri T: DNA methylation from embryo to adult. Prog Nucleic Acid Res Mol Biol 1994, 48:53-81.
25. Feil R, Walter J, Allen ND, Reik W: Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes. Development 1994, 120:2933-2943.
26. Neumann B, Kubicka P, Barlow DP: Characteristics of imprinted genes. Nature Genet 1995, 9:12-13. It is argued that elements that are CG-rich and contain direct repeats are associated with imprinted genes.
27. Hatada I, Mukai T: Genomic imprinting of p57kip2, a cyclin dependent kinase inhibitor in mice. Nature Genet 1995, 11:204-207. Identification of a novel imprinted gene which is novel by virtue of its association with a CpG island rich in direct repeats.
28. Smrzka O, Fae I, Stöger R, Kurzbauer R, Fischer GF, Weith A, Barlow DP: Conservation of a maternal-specific methylation signal at the human IGF2R locus. Hum Mol Genet 1995, 4:1945-1952.
29. Riesewijk AM, Schepens MT, Welch TR, Bierg-Loonen EM, Mariman EM, Ropers H-H, Kalscheuer VM: Maternal methylation of the human IGF2R gene is not accompanied by allele-specific transcription. Genomics 1996, in press.
30. Cross SH, Bird AP: CpG islands and genes. Curr Opin Genet Dev 1995, 5:309-314.
31. Macleod D, Charlton J, Mullins J, Bird AP: Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev 1994, 8:2282-2292.
32. Brandeis M, Frank D, Keshet I, Siegfried Z, Mendelsohn M, Nemes A, Temper V, Ceder H: Sp1 sites protect a CpG island from de novo methylation. Nature 1994, 371:435-438.
33. Mummaneni P, Walker KA, Bishop PL, Turker MS: Epigenetic gene inactivation induced by a cis-acting methylation center. J Biol Chem 270:788-792.
34. Stöger R, Kubicka P, Liu C-G, Kafri T, Razin A, Cedar H, Barlow DP: Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 1993, 73:1-11.
35. Latham KE, Doherty AS, Scott CD, Schultz RM: Igf2r and Igf2 gene expression in androgenetic, gynogenetic and parthenogenetic preimplantation mouse embryos: absence of regulation by genomic imprinting. Genes Dev 1994, 8:290-299.
36. Moulton T, Crenshaw T, Hao Y, Moosikasuwan J, Lin N, Dembitzer F, Hensle T, Wiess L, McMorrow L, Loew T et al.: Epigenetic lesions at the H19 locus in Wilms' tumor patients. Nature Genet 1994, 7:440-447.
37. Buiting K, Saitoh S, Gross S, Dittrich B, Schwartz S, Nicholls RD, Horsthemke B: Inherited microdeletions in the Angelman and Prader-Willi syndromes define an imprinting center on human chromosome 15. Nature Genet 1995, 9:395-400. Demonstration that deletion of part of the imprinted SNRPN genes regulates in cis the imprinted expression of two other genes in the Prader-Willi consensus region.
38. Leighton PA, Ingram RS, Eggenschwiler J, Efstratiadis A, Tilghman SM: Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 1995, 375:34-39. A deletion of the imprinted H19 gene regulates in cis the imprinted expression of two upstream genes.
39. Kitsberg D, Selig S, Brandeis M, Simon I, Keshet I, Driscoll DJ, Nicholls RD, Cedar H: Allele-specific replication timing of imprinted gene regions. Nature 1993, 364:459-463.
40. Knoll JHM, Cheng S-D, Lalande M: Allele specificity of DNA replication timing in the Angelman/Prader-Willi syndrome region. Nature Genet 1993, 6:41-46.
41. Deltour L, Montagutelli X, Guenet J-L, Jami J, Paldi A: Tissue and developmental stage specific imprinting of the mouse proinsulin gene Ins2. Dev Biol 1995, 168:686-689.
42. Villar AJ, Pederson RA: Parental imprinting of the mas protooncogene in the mouse. Nature Genet 1994, 8:373-377.
43. Hatada I, Kitagawa K, Yamaoka T, Wang X, Arai Y, Hashido K, Ohishi S, Masuda J, Ogata J, Mukai T: Allele specific methylation and expression of an imprinted U2af1-rs1[SP2] gene. Nucleic Acids Res 1995, 23:36-41.
44. Glenn CG, Saitoh S, Jong MTC, Filbrandt MM, Surti U, Driscoll DJ, Nicholls RD: Gene structure, DNA methylation, and imprinted gene expression of the human SNRPN gene. Am J Hum Genet 1996, in press.
45. Hayashizaki Y, Shibata H, Hirotsune S, Sugino H, Okazaki Y, Sasaki N, Hirose K, Imoto H, Okuizumi H, Muramatsu M et al.: Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method. Nature Genet 1993, 6:33-39.