Synaptophysin expression in the anterior horn of Werdnig-Hoffmann disease

Journal of the Neurological Sciences

Volumn 136, Issue 1-2, 1996, Pages 94-100

  Ikemoto, Akito ^a   Hirano, Asao ^a   Matsumoto, Sadayuki ^b   Akiguchi, Ichiro ^c   Kimura, Jun ^c  

^a MONTEFIORE MEDICAL CENTER   (United States)

^b Kitano Hospital   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Anterior horn cell; Axonal reaction; Ballooned neuron; Immunohistochemistry; Motor neuron disease; Presynaptic terminal; Synaptophysin; Werdnig Hoffmann disease

Indexed keywords

SYNAPTOPHYSIN;

ARTICLE; CASE REPORT; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MOTOR NEURON DISEASE; PRIORITY JOURNAL; SPINAL CORD VENTRAL HORN; WERDNIG HOFFMANN DISEASE;

EID: 0029985237     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-510X(95)00297-F     Document Type: Article

References (23)

1. Chou, S.M. and Fakadej, A.V. (1971) Ultrastructure of chromatolytic motoneurons and anterior spinal roots in a case of Werdnig-Hoffmann disease. J. Neuropathol. Exp. Neurol., 30: 368-379.
2. DeLeon, G.A., Grover, W.D. and D'Guss, C.A. (1984) Amyotrophic cerebellar hypoplasia: a specific form of infantile spinal atrophy. Acta Neuropathol., 63: 282-286.
3. Delisle, M.B. and Carpenter, S. (1981) Neurofibrillary axonal swelling and amyotrophic lateral sclerosis. J. Neurol. Sci., 63: 241-250.
4. Goto, S., Hirano, A. and Rojas-Carona, R.R. (1989) A comparative immunocytochemical study of human cerebellar cortex in X-chro-mosome-linked copper malabsorption (Menkes' kinky hair disease) and granule cell type cerebellar degeneration. Neuropathol. Appl. Neurobiol., 15: 419-431.
5. Graeber, M.B., Streit, W.J. and Kreutzberg, G.W. (1990) The glial response to motor neuron axotomy: role of microglia and astrocytes. In: Yonezawa, T. (Ed.), Proceedings of the 11th International Congress of Neuropathology, held in Kyoto, September 2-8, Neuropathology, Suppl. 4, pp. 282-287.
6. Graeber, M.B., Bise, K. and Mehraein, P. (1993) Synaptic stripping in the human facial nucleus. Acta Neuropathol., 86: 179-181.
7. Hirano, A. (1982) Aspects of the ultrastructure of amyotrophic lateral sclerosis. In: Rowland, L.P. (Ed.), Human motor neuron diseases, Raven Press, New York, pp. 75-88.
8. Ikemoto, A., Kawanami, T., Llena, J.F. and Hirano, A. (1994) Immunocytochemical studies on synaptophysin in the anterior horn of lower motor neuron disease. J. Neuropathol. Exp. Neurol., 53: 196-201.
9. Ikemoto, A. and Hirano, A. (1995) Immunohistochemical study on synaptophysin in the spinal cord of chronic anterior poliomyelitis. In: Dalakas, M., Bartfeld, H., Kurland, L.T. (Eds.), The post-polio syndrome: advances in the pathogenesis and treatment. Ann. N.Y. Acad. Sci., 753: 381-382.
10. Inoue, K. and Hirano, A. (1979) Early pathological changes of amyotrophic lateral sclerosis: autopsy findings of a case of 10 months' duration. Neurol. Med. (Jpn.), 11: 448-455.
11. Iwata, M. and Hirano, A. (1978a) A neuropathological study of the Werdnig-Hoffmann disease. Neurol. Med. (Jpn.), 8: 40-53.
12. Iwata, M. and Hirano, A. (1978b) A neuropathological study of healed chronic anterior poliomyelitis. Neurol. Med. (Jpn.), 8: 334-343.
13. Iwata, M. and Hirano, A. (1979) A neuropathological study of amyotrophic lateral sclerosis. Neurol. Med. (Jpn.), 11: 569-594.
14. Jahn, R., Schiebler, W., Ouimet, C. and Greengard, P. (1985) A 38,000 dalton membrane protein (p38) present in synaptic vesicles. Proc. Natl. Acad. Sci. USA, 82: 4137-4141.
15. Kato, S. and Hirano, A. (1990) Ubiquitin and phosphorylated neurofilament epitopes in ballooned neurons of the extraocular muscle nuclei in a case of Werdnig-Hoffmann disease. Acta Neuropathol., 80: 334-337.
16. Kato, S., Hirano, A., Umahara, T., Llena, J.F., Herz, F. and Ohama, E. (1992) Ultrastructual and immunohistochemical studies on ballooned cortical neurons in Creutzfeldt-Jakob disease: expression of αB-crystallin, ubiquitin and stress-response protein 27. Acta Neuropathol., 84: 443-448.
17. Kawanami, T., Ikemoto, A., Llena, J.F. and Hirano, A. (1993) Synaptophysin immunoreactivity pattern in the anterior horn cells in amyotrophic lateral sclerosis (Abstract). Can. J. Neurol. Sci., 20: 75.
18. Matsumoto, S., Goto, S., Kusaka, H. et al. (1993) Ubiquitin-positive inclusion in anterior horn cells in subgroups of motor neuron diseases: a comparative study of adult-onset amyotrophic lateral sclerosis, juvenile amyotrophic lateral sclerosis and Werdnig-Hoffman disease. J. Neurol. Sci., 115: 208-213.
19. Matsumoto, S,. Kusaka, H., Ito, H. and Imai, T. (1994) Immunohistochemical study of synaptic alterations of spinal anterior horn cells in motor neuron diseases (Abstract). Brain Pathol., 4: 527.
20. Mizusawa, H. and Hirano, A. (1991) Chromatolytic neurons in WerdnigHoffmann disease. Neurol. Med. (Jpn.), 34: 413-415.
21. Murayama, S., Bouldin, T.W. and Suzuki, K. (1991) Immunocytochemical and ultrastrucrual studies of Werdnig-Hoffman disease. Acta Neuropathol., 81: 408-417.
22. Navone, F., Jahn, R., Digioia, G., Stukenbrok, H., Greengard, P. and DeCamilli, P. (1986) Protein p38: an integral protein specific for small vesicles of neurons and neuroendocrine cells. J. Cell Biol., 103: 2511-2527.
23. Rhen, H., Wiedenmann, B. and Betz, H. (1986) Molecular characterization of synaptophysin, a major calcium-binding protein of the presynaptic vesicle membrane. EMBO J., 5: 535-541.