Convenient preparation of di- and tri-ethynylbenzenes by cleavage of 2-hydroxy-2-methylbut-3-yn-4-yl-benzenes with water miscible reagents

Synthetic Communications

Volumn 26, Issue 12, 1996, Pages 2309-2316

  MacBride, J A Hugh ^a   Wade, Kenneth ^a  

^a DURHAM UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE DERIVATIVE; BENZENE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; TECHNIQUE;

EID: 0029984996     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919608004542     Document Type: Article

References (23)

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16. See e.g. Catalogue for 1995-6 Aldrich Chemical Company.
17. We observed rapid volatilisation of 1,4-diethynylbenzene on the rotary evaporator at ca. 45°C bath temperature. Ref. 11 reports deprotection of this compound using toluene with quantitative recovery, but without details of the evaporation conditions.
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19. Reactions of the alkynes described in this paper with decaborane derivatives will be described elsewhere.
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