Trophoblast function in normal and preeclamptic pregnancy

Fetal and Maternal Medicine Review

Volumn 8, Issue 2, 1996, Pages 57-66

  Cross, James C ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FETOPLACENTAL UNIT; FETUS HYPOXIA; HUMAN; INTRAUTERINE GROWTH RETARDATION; PLACENTA DEVELOPMENT; PREECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATION; REVIEW; SPONTANEOUS ABORTION; TROPHOBLASTIC DISEASE;

EID: 0029984975     PISSN: 09655395     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0965539500001492     Document Type: Review

References (91)

1. Roberts JM, Taylor RN, Friedman SA, Goldfien A. New developments in preeclampsia. Fetal and maternal medicine review 1990; 2: 125-141.
2. Redman CW. Current topic: preeclampsia and the placenta. Placenta 1991; 12: 301-308.
3. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 1989; 161: 1200-204.
4. Cross JC, Werb Z, Fisher SJ. Implantation and the placenta: key pieces of the development puzzle. Science 1994; 266: 1508-518.
5. Fisher SJ, Damsky CH. Human cytotrophoblast invasion. Semin Cell Biol 1993; 4: 183-88.
6. Fisher SJ, Cui T-Y, Zhang L, Hartman L, Grahl K, Zhang G-Y et al. Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. J Cell Biol 1989; 109: 891-902.
7. Genbacev O, White TEK, Gavin CE, Miller RK. Human trophoblast cultures: models for implantation and peri-implantation toxicology. Reprod Toxicol 1993; 7: 75-94.
8. Damsky CH, Fitzgerald ML, Fisher SJ. Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway in vivo. J Clin Invest 1992; 89: 210-22.
9. Damsky CH, Librach C, Lim KH, Fitzgerald ML, McMaster MT, Janatpour M et al. Integrin switching regulates normal trophoblast invasion. Development 1994; 120: 3657-66.
10. Librach CL, Werb Z, Fitzgerald ML, Chiu K, Corwin NM, Esteves RA et al. 92-kD type IV collagenase mediates invasion of human cytotrophoblasts. J Cell Biol 1991; 113: 437-49.
11. Pijnenborg R, Dixon G, Robertson WB, Brosens I. Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnancy. Placenta 1980; 1: 3-19.
12. Moore KL, Persaud TVN, Shiota K. Placenta and fetal membranes. Color atlas of clinical embryology. Toronto Canada: WB Saunders Company, 1994: 79-104.
13. Jaffe R, Genbacev O. In vivo assessment of the early uteroplacental circulation. Am J Obstet Gynecol 1993; 169: 1077.
14. Jaffe R, Dorgan A, Abramowicz JS. Color Doppler imaging of the uteroplacental circulation in the first trimester: value in predicting pregnancy failure or complication. Am J Roentgenol 1995; 164: 1255-58.
15. Jauniaux E, Zaidi J, Jurkovic D, Campbell S, Hustin J. Comparison of colour Doppler features and pathological findings in complicated early pregnancy. Hum Reprod 1994; 9: 2432-37.
16. Kurjak A, Zudenigo D, Funduk-Kurjak B, Shalan H, Predanic M, Sosic A. Transvaginal color Doppler in the assessment of the uteroplacental circulation in normal early pregnancy. J Perinat Med 1993; 21: 25-34.
17. Jauniaux E, Jurkovic D, Campbell S, Hustin J. Doppler ultrasonographic features of the developing placental circulation: correlation with anatomic findings. Am J Obstet Gynecol 1992; 166: 585-87.
18. Jurkovic D, Jauniaux E, Kurjak A, Hustin J, Campbell S, Nicolaides KH. Transvaginal color Doppler assessment of the uteroplacental circulation in early pregnancy. Obstet Gynecol 1991; 77: 365-69.
19. Thaler I, Manor D, Itskovitz J, Rottem S, Levit N, Timor-Tritsch I et al. Changes in uterine blood flow during human pregnancy. Am J Obstet Gynecol 1990; 162: 121-25.
20. Matijevic R, Meekins JW, Walkinshaw SA, Neilson JP, McFadyen IR. Spiral artery blood flow in the central and peripheral areas of the placental bed in the second trimester. Obstet Gynecol 1995; 86: 289-92.
21. Curran-Everett D, Morris KG, Moore LG. Regional circulatory contributions to increased systemic vascular conductance of pregnancy. Am J Physiol 1991; 261 H1842-47.
22. Malassine A, Cronier L, Mondon F, Mignot TM, Ferre F. Localization and production of immunoreactive endothelin-1 in the trophoblast of human placenta. Cell Tissue Res 1993; 271: 491-97.
23. Ferre F, Mondon D, Mignot TM, Cronier L, Cavero I, Rostene W et al. Endothelin-1 binding sites and immunoreactivity in the cultured human placental trophoblast: evidence for an autocrine and paracrine role for endothelin-1. J Cardiovasc Pharmacol 1993; 22 (Suppl. 8): S214-18.
24. Myatt L. Current topic: control of vascular resistance in the human placenta. Placenta 1992; 13: 329-41.
25. Magann EF, Martin JN. The laboratory evaluation of hypertensive gravidas. Obstet Gynecol Surv 1995; 50: 138-45.
26. Redman CW. Platelets and the beginnings of preeclampsia. N Engl J Med 1990; 323: 478-80.
27. Friedman SA, Taylor RN, Roberts JM. Pathophysiology of preeclampsia. Clin Perinatol 1991; 18: 661-82.
28. Brown MA. The physiology of preeclampsia. Clin Exp Pharmacol Physiol 1995; 22: 781-91.
29. Eskenazi B, Fenster L, Sidney S. A multivariate analysis of risk factors for preeclampsia. JAMA 1991; 266: 237-41.
30. Sibai BM, Gordon T, Thom E, Caritis SN, Klebanoff M, McNellis D et al. Risk factors for preeclampsia in healthy nulliparous women: a prospective multicenter study. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. Am J Obstet Gynecol 1995; 172: 642-48.
31. Arngrimsson R, Bjornsson H, Geirsson RT. Analysis of different inheritance patterns in preeclampsia/eclampsia syndrome. Hypertens Pregnancy 1995; 14: 27-38.
32. Ward K, Hata A, Jeunemaitre X, Helin C, Nelson L, Namikawa C et al. A molecular variant of angiotensinogen associated with preeclampsia. Nat Genet 1993; 4: 59-61.
33. Zamudio S, Droma T, Norkyel KY, Acharya G, Zamudio JA, Niermeyer SN et al. Protection from intrauterine growth retardation in Tibetans at high altitude. Am J Phys Anthropol 1993; 91: 215-24.
34. Reshetnikova OS, Burton GJ, Milovanov AP. Effects of hypobaric hypoxia on the fetoplacental unit: the morphometric diffusing capacity of the villous membrane at high altitude. Am J Obstet Gynecol 1994; 171: 1560-65.
35. Arnholdt H, Meisel F, Fandrey K, Lohrs U. Proliferation of villous trophoblast of the human placenta in normal and abnormal pregnancies. Virchows Archiv B Cell Pathol incl Mol Pathol 1991; 60: 365-72.
36. Genbacev O, Bass KE, Joslin RJ, Fisher SJ. Maternal smoking inhibits early human cytotrophoblast differentiation. Reprod Toxicol 1995; 9: 245-55.
37. Teasdale F, Ghislaine J-J. Morphological changes in the placentas of smoking mothers: a histomorphometric study. Biol Neonate 1989; 55: 251-59.
38. Spinillo A, Capuzzo E, Egbe TO, Nicola S, Piazzi G, Baltaro F. Cigarette smoking in pregnancy and risk of pre-eclampsia. J Hum Hypertens 1994; 8: 771-75.
39. Klonoff-Cohen H, Edelstein S, Savitz D. Cigarette smoking and preeclampsia. Obstet Gynecol 1993; 81: 541-44.
40. Redman CW. Immunological aspects of preeclampsia. Baillieres Clin Obstet Gynaecol 1992; 6: 601-15.
41. Teasdale F. Histomorphometry of the human placenta in maternal preeclampsia. Am J Obstet Gynecol 1985; 152: 25-31.
42. Fox H. The villous cytotrophoblast as an index of placental ischaemia. J Obstet Gynaecol Br Commonw 1964; 71: 885-93.
43. Redline RW, Patterson P. Pre-eclampsia is associated with an excess of proliferative immature intermediate trophoblast. Hum Pathol 1995; 26: 594-600.
44. Jones CJP, Fox H. An ultrastructural and ultrahistochemical study of the human placenta in maternal pre-eclampsia. Placenta 1980; 1: 61-76.
45. Jackson MR, Walsh AJ, Morrow RJ, Mullen JB, Lye SJ, Ritchie JW. Reduced placental villous tree elaboration in small-for-gestational-age pregnancies: relationship with umbilical artery Doppler waveforms. Am J Obstet Gynecol 1995; 172: 518-25.
46. Fuke Y, Aono T, Imai S, Suehara N, Fujita T, Nakayama M. Clinical significance and treatment of massive intervillous fibrin deposition associated with recurrent fetal growth retardation. Gynecol Obstet Invest 1994; 38: 5-9.
47. Robertson WB, Brosens I, Dixon G. Uteroplacental vascular pathology. Eur J Obstet Gynecol Reprod Biol 1975; 5: 47-65.
48. Gerretsen G, Huisjes HJ, Elema JD. Morphological changes of the spiral arteries in the placental bed in relation to pre-eclampsia and fetal growth retardation. Br J Obstet Gynaecol 1981; 88: 876-81.
49. Khong TY, De Wolf F, Robertson WB, Brosens I. Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small-for-gestational age infants. Br J Obstet Gynaecol 1986; 93: 1049-59.
50. Brosens IA, Robertson WB, Dixon HG. The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet Gynecol Ann 1972; 1: 177-91.
51. Lin S, Shimizu I, Suehara N, Nakayama M, Aono T. Uterine artery Doppler velocimetry in relation to trophoblast migration into the myometrium of the placental bed. Obstet Gynecol 1995; 85: 760-65.
52. Iwata M, Matsuzaki N, Shimizu I, Mitsuda N, Nakayama M, Suehara N. Prenatal detection of ischemic changes in the placenta of the growth-retarded fetus by Doppler flow velocimetry of the maternal uterine artery. Obstet Gynecol 1993; 82: 494-99.
53. Khong TY, Sawyer IH, Heryet AR. An immunohistologic study of endothelialization of uteroplacental vessels in human pregnancy. Evidence that endothelium is focally disrupted by trophoblast in preeclampsia. Am J Obstet Gynecol 1992; 167: 751-56.
54. Zhou Y, Damsky CH, Chiu K, Roberts JM, Fisher SJ. Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts. J Clin Invest 1993; 91: 950-60.
55. Lim KH, Damsky C, Fisher SJ. Differentiation of invasive cytotrophoblasts in normal and abnormal pregnancy. Soc Gynecol Invest 1993; abstract no. S166.
56. Roberts JM, Taylor RN, Goldfen A. Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia. Am J Hypertens1991; 4: 700-708.
57. Zeeman GG, Dekker GA. Pathogenesis of preeclampsia: a hypothesis. Clin Obstet Gynecol 1992; 35: 317-37.
58. Rodesch F, Simon P, Donner C, Jauniaux E. Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet Gynecol 1992; 80: 283-85.
59. Watson AL, Palmer ME, Burton GJ. Problems associated with oxygen tension in the maintenance of first trimester placental tissue in organ culture. Placenta 1995; 16: A.75.
60. Janatpour MJ, Israel MA, Fisher SJ. The transcriptional negative regulator Id-2 can control MMP-9 expression. Mol Biol Cell 1995; Suppl 6: 304a, abstract 1768.
61. Tominaga T, Page E. Accommodation of the human placenta to hypoxia. Am J Obstet Gynecol 1966; 94: 679-91.
62. MacLennan AH, Sharp F, Shaw-Dunn J. The ultrastructure of human trophoblast in spontaneous and induced hypoxia using a system of organ culture: a comparison with ultrastructural changes in pre-eclampsia and placental insufficiency. J Obstet Gynaecol Br Commonw 1972; 79: 113-21.
63. Karimu AL, Burton GJ. Significance of changes in fetal perfusion pressure to factors controlling angiogenesis in the human term placenta. J Reprod Fertil 1994; 102: 447-50.
64. Lunell NO, Nylund LE, Lewlander R, Sarby B. Uteroplacental blood flow in pre-eclampsia. Measurements with indium-113m and a computer-linked gamma camera. Clin Exp Hypertens [Part B] 1982; 1: 105-17.
65. Kraayenbrink AA, Dekker GA, van Kamp GJ, van Geijn HP. Endothelial vasoactive mediators in preeclampsia. Am J Obstet Gynecol 1993; 169: 160-65.
66. Vince GS, Starkey PM, Austgulen R, Kwiatkowski D, Redman CW. Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with preeclampsia. Br J Obstet Gynaecol 1995; 102: 20-25.
67. Pahl HL, Baeuerle PA. Oxygen and the control of gene expression. Bioessays 1994; 16: 497-502.
68. Endresen MJ, Lorentzen B, Henriksen T. Increased lipolytic activity and high ratio of free fatty acids to albumin in sera from women with preeclampsia leads to triglyceride accumulation in cultured endothelial cells. Am J Obstet Gynecol 1992; 167: 440-47.
69. Lorentzen B, Drevon CA, Endresen MJ, Henriksen T. Fatty acid pattern of esterified and free fatty acids in sera of women with normal and pre-eclamptic pregnancy. Br J Obstet Gynaecol 1995; 102: 530-37.
70. Walsh SW, Wang Y. Trophoblast and placental villous core production of lipid peroxides, thromboxane, and prostacyclin in preeclampsia. J Clin Endocrinol Metab 1995; 80: 1888-93.
71. Johnson MR, Riddle AF, Grundzinskas JG, Sharma V, Collins WP, Nicolaides KH. The role of trophoblast dysfunction in the aetiology of miscarriage. Br J Obstet Gynaecol 1993; 100: 353-59.
72. Jaffe R. Investigation of abnormal first-trimester gestations by color Doppler imaging. J Clin Ultrasound 1993; 21: 521-26.
73. Kurjak A, Zudenigo D, Predanic M, Kupesic S, Funduk B. Assessment of the fetomaternal circulation in threatened abortion by transvaginal color Doppler. Fetal Diagn Ther 1994; 9: 341-47.
74. Khong TY, Liddell HS, Robertson WB. Defective haemochorial placentation as a cause of miscarriage: a preliminary study. Br J Obstet Gynaecol 1987; 94: 649-55.
75. De Wolf F, Brosens I, Renaer M. Fetal growth retardation and the maternal arterial supply of the human placenta in the absence of sustained hypertension. Br J Obstet Gynaecol 1980; 87: 678-85.
76. Brosens I, Dixon HG, Robertson WB. Fetal growth retardation and the arteries of the placental bed. Br J Obstet Gynaecol 1977; 84: 656-63.
77. Althabe O, Labarrere C, Telenta M. Maternal vascular lesions in placentae of small-for-gestational infants. Placenta 1985; 6: 265-76.
78. Jones CJP, Fox H. An ultrastructural and ultrahistochemical study of the human placenta in maternal essential hypertension. Placenta 1981; 2: 193-204.
79. Naeye RL. Pregnancy hypertension, placental evidences of low uteroplacental blood flow and spontaneous premature delivery. Hum Pathol 1989; 20: 441-44.
80. Strigini FA, Lencioni G, De Luca G, Lombardo M, Bianchi F, Genazzani AR. Uterine artery velocimetry and spontaneous preterm delivery. Obstet Gynecol 1995; 85: 374-77.
81. Nicotra M, Muttinelli C, Sbracia M, Rolfi G, Passi S. Blood levels of lipids, lipoperoxides, vitamin E and glutanthione peroxidase in women with habitual abortion. Gynecol Obstet Invest 1994; 38: 223-26.
82. Zhou Y, Chiu K, Brescia RJ, Combs CA, Katz MA, Kitzmiller JL et al. Increased depth of trophoblast invasion after chronic constriction of the lower aorta in rhesus monkeys. Am J Obstet Gynecol 1993; 169: 224-29.
83. Hoffman LH, Wooding FBP. Giant and binucleate trophoblast cells of mammals. J Exp Zool 1993; 266: 559-77.
84. McKay DG, Goldenberg V, Kaunitz H, Csavossy I. Experimental eclampsia: an electron microscope study and review. Arch Path 1967; 84: 557-97.
85. Faas MM, Schuiling GA, Baller JFW, Visscher CA, Bakker WW. A new animal model for human preeclampsia: ultra-low-dose endotoxin infusion in pregnant rats. Am J Obstet Gynecol 1994; 171: 158-64.
86. Chari RS, Friedman SA, Sibai BM. Antihypertensive therapy during pregnancy. Fet Mat Med Rev 1995; 7: 61-75.
87. Brennecke SP, Brown MA, Crowther CA, Hague WM, King J, McCowan L et al. Aspirin and prevention of preeclampsia. Position statement of the use of low-dose aspirin in pregnancy by the Australasian Society for the Study of Hypertension in Pregnancy. Aust N Z J Obstet Gynaecol 1995; 35: 38-41.
88. Dekker GA, Sibai BM. Low-dose aspirin in the prevention of preeclampsia and fetal growth retardation: rationale, mechanisms and clinical trials. Am J Obstet Gynecol 1993; 168: 214-27.
89. Uotila JT, Tuimala RJ, Aarnio TM, Pyykko KA, Ahotupa MO. Findings on lipid peroxidation and antioxidant function in hypertensive complications of pregnancy. Br J Obstet Gynaecol 1993; 100: 270-76.
90. Valsecchi L, Fausto A, Grazioli V. Severe preeclampsia and antioxidant nutrients. Am J Obstet Gynecol 1995; 173: 773-74.
91. Bower S, Bewley S, Campbell S. Improved prediction of preeclampsia by two-stage screening of uterine arteries using the early diastolic notch and color Doppler imaging. Obstet Gynecol 1993; 82: 78-83.