Plasmodium falciparum lacks sialidase and trans-sialidase activity

Parasitology

Volumn 112, Issue 5, 1996, Pages 443-449

  Clough, B ^a   Atilola, F A ^a   Healy, N ^b   Pereira, M E A ^c   Bethell, R C ^b   Penn, C R ^b   Pasvol, G ^a  

^a NORTHWICK PARK HOSPITAL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c TUFTS MEDICAL CENTER   (United States)

Author keywords

cytoadherence; invasion; malaria; rosetting; sialidase

Indexed keywords

ANTIMALARIAL AGENT; ENZYME INHIBITOR; SIALIDASE;

ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ERYTHROCYTE; HOST PARASITE INTERACTION; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

EID: 0029984933     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0031182000076903     Document Type: Article

References (24)

1. AL-YAMAN, F., GENTON, B., MOKELA, D., RAIKO, A., KATI, S., ROGERSON, S., REEDER, J. & ALPERS, M. (1995). Human cerebral malaria: lack of significant association between erythrocyte rosetting and disease severity. Transactions of the Royal Society of Tropical Medicine and Hygiene 89, 55-8.
2. DLUZEWSKI, A. R., LING, I. T., RANGACHARI, K., BATES, P. A. & WILSON, R. J. M. (1984). A simple method for isolating viable mature parasites of Plasmodium falciparum from cultures. Transactions of the Royal Society for Tropical Medicine and Hygiene 78, 622-4.
3. k). Journal of Clinical Investigation 80, 1190-3.
4. HOWARD, R. J. (1982). Alterations in the surface membrane of red blood cells during malaria. Immunological Reviews 61, 67-107.
5. HOWARD, R. J., BROWN, G. V., SMITH, P. M., MITCHELL, G. F., STACE, J. D., ALPERS, M. P., WEMBER, M. & SCHAUER, R. (1981). Studies on malaria in Papua New Guinea. I. Comparison of the surface glycoproteins on red cells from infected and uninfected individuals. Parasitology 83, 357-72.
6. MAC-PHERSON, G. G., WARRELL, M. J., WHITE N. J., LOOAREESUWAN, S. & WARRELL, D. A. (1985). Human cerebral malaria: a quantitative structural analysis of parasitised erythrocyte sequestration. American Journal of Pathology 119, 385-401.
7. MAKLER, M. T. (1987). P. falciparum invasion of human red cells and cytoadherence to endothelial cells is dependent upon a parasite produced glycosidase. Biochemical and Biophysical Research Communications 143, 461-6.
8. MARSH, K., OTOO, L., HAYES, R. J., CARSON, D. C. & GREENWOOD, D. M. (1989). Antibodies to blood stage antigens of Plasmodium falciparum and their relation to protection against infection. Transactions of the Royal Society of Tropical Medicine and Hygiene 83, 293-303.
9. MITCHELL, G. H., HADLEY, T. J., MCGINNIS, M. H., KLOTZ, F. W. & MILLER, L. H. (1986). Invasion of erythrocytes by Plasmodium falciparum malaria parasites: evidence for receptor heterogeneity and two receptors. CRC Critical Reviews in Oncology/Haematology 8, 225-310.
10. ORLANDI, P. A., KLOTZ, F. W. & HAYNES, J. D. (1992). A malaria invasion receptor, the 175 kilodalton erythrocyte binding antigen of Plasmodium falciparum recognises the terminal Neu5Ac(a2-3)Gal-sequences of glycophorin A. Journal of Cell Biology 116, 901-9.
11. PASVOL, G., JUNGERY, M., WEATHERALL, D. J., PARSONS, S. F., ANSTEE, D. J. & TANNER, M. J. A. (1982b). Glycophorin as a possible receptor for Plasmodium falciparum. Lancet 2, 947-50.
12. PASVOL, G., WAINSCOAT, J. S. & WEATHERALL, D. J. (1982a). Erythrocytes deficient in glycophorin resist invasion by the malarial parasite Plasmodium falciparum. Nature, London 297, 64-6.
13. PELLEGRIN, J. L. J., ORTEGA-BARRIA, E., PRIOLI, R. P., BUERGER, M., STROUT, R. G., ALROY, J. & PEREIRA, M. E. A. (1993). Identification of a developmentally regulated sialidase in Eimeria tenella that is immunologically related to the Trypanosoma cruzi enzyme. Glycoconjugate Journal 10, 57-63.
14. PEREIRA, M. E. A. (1983a). A developmentally regulated neuraminidase activity in Trypanosoma cruzi. Science 219, 1444-6.
15. PEREIRA, M. E. A. (1983b). A rapid and sensitive assay for neuraminidase using peanut lectin haemagglutination : application to Vibrio cholera and Trypanosoma cruzi. Journal of Immunological Methods 63, 25-34.
16. POTIER, M., MAMELI, L., BELISLE, M., DALLAIRE, L. & MELANCON, S. B. (1979). Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-a-D-N-acetylneuraminate) substrate. Analytical Biochemistry 94, 287-96.
17. SCHAUER, R., WEMBER, M. & HOWARD, R. J. (1984). Malaria parasites do not contain or synthesise sialic acids. Hoppe-Seyler's Zeitschrift für physiologische Chemie 365, 185-94.
18. SCUDDER, P., DOOM, J. P., CHUENKOVA, M., MANAGER, I. D. & PEREIRA, M. E. A. (1993). Enzymatic characterization of β-D-galactoside a 2,3-trans-sialidase from Trypanosoma cruzi. Journal of Biological Chemistry 268, 9886-91.
19. SHERMAN, I. W. & JONES, L. A. (1979). Plasmodium lophurae: Membrane proteins of erythrocyte-free plasmodia and malaria-infected red cells. Journal of Protozoology 26, 489-501.
20. TRAGER, W. & JENSEN, J. B. (1976). Human malaria parasites in continuous culture. Science 193, 673-5.
21. TREUTIGER, C. J., HEDLUND, I., HELMBY, H., CARLSON, J., JEPSON, A., TWUMASI, P., KWAITKOWSKI, D., GREENWOOD, B. M. & WAHLGREN, M. (1992). Rosette formation in Plasmodium falciparum isolates and anti-rosette activity of sera from Gambians with cerebral or uncomplicated malaria. American Journal of Tropical Medicine and Hygiene 46, 503-10.
22. UDOMSANGPETCH, R., WAHLIN, B., CARLSON, J., BERZINS, K., TORII, M., AIKAWA, M., PERLMANN, P. & WAHLGREN, M. (1989). Plasmodium falciparum-infected erythrocytes form spontaneous erythrocyte rosettes. Journal of Experimental Medicine 169, 1835-40.
23. VON ITZSTEIN, M., WU, M. Y., KOK, G. B., PEGG, M. S., DYASON, J. C., JIN, B., PHAN, T. V., SMYTHE, M. L., WHITE, H. F., OLIVER, S. W., COLMAN, P. M., VARGHESE, J. N., RYAN, D. M., WOODS, J. M., BETHELL, R. C., HOTHAM, V. J., CAMERON, J. M. & PENN, C. R. (1993). Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature, London 363, 418-23.
24. ZOUALI, M., DRUILHE, P., GENTILINI, M. & EYQUEM, A. (1982). High titres of anti-T antibodies and other haemagglutinins in human malaria. Clinical Experimental Immunology 50, 83-91.