Adrenal gland volume in major depression: Relationship to basal and stimulated pituitary-adrenal cortical axis function

Biological Psychiatry

Volumn 40, Issue 2, 1996, Pages 89-97

  Rubin, Robert T ^a,d   Phillips, Jeffrey J ^b   McCracken, James T ^c   Sadow, Todd F ^b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b HARBOR UCLA MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ALLEGHENY GENERAL HOSPITAL   (United States)

Author keywords

ACTH; adrenal cortex; adrenal volume; cortisol; CRH; magnetic resonance imaging; pituitary gland

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE;

ADRENAL GLAND; ADULT; ANXIETY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; PRIORITY JOURNAL; SOMATIZATION; VOLUMETRY;

EID: 0029984024     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-3223(95)00358-4     Document Type: Article

References (42)

1. American Psychological Association (1987): Diagnostic and Statistical Manual of Mental Disorders (Third Edition-Revised). American Psychiatric Association Press, Washington, DC.
2. Amsterdam JD, Marinelli DL, Arger P, Winokur A (1987): Assessment of adrenal gland volume by computed tomography in depressed patients and healthy volunteers: a pilot study. Psychiatry Res 21:189-197.
3. Amsterdam JD, Maislin G, Berwish N, Phillips J, Winokur A (1989): Enhanced adrenocortical sensitivity to submaximal doses of cosyntropin (alpha-24-corticotropin) in depressed patients. Arch Gen Psychiatry 46:550-554.
4. Azziz R, Bradley E Jr, Huth J, Boots LR, Parker CR Jr, Zacur HA (1990): Acute adrenocorticotropin-(1-24) (ACTH) adrenal stimulation in eumenorrheic women: Reproducibility and effect of ACTH dose, subject weight, and sampling time. J Clin Endocrinol Metab 70:1273-1279.
5. Carroll BJ (1976): Limbic system-adrenal cortex regulation in depression and schizophrenia. Psychosom Med 38:106-121.
6. Chang PC, Rubin RT, Yu M (1975): Optimal statistical design of radioimmunoassays and competitive protein binding assays. Endocrinology 96:973-981.
7. Charlton BG (1995): Noradrenergic innervation to the adrenal cortex is responsible for control of basal glucocorticoid secretion: A model. Med Hypotheses 44:214-216.
8. Chrousos GP, Luger A, Avgerinos PC, Kling MA, Oldfield EE, Nieman K, Schuermeyer T, Loriaux DL, Gold PW (1987): Corticotropin-releasing hormone: Relevance to human physiology and pathophysiology. In D'Agata R, Loriaux L, Chrousos GP (eds), Recent Advances in Adrenal Regulation and Function. Raven Press, New York, pp 121-136.
9. Dorovini-Zis K, Zis AP (1987): Increased adrenal weight in victims of violent suicide. Am J Psychiatry 144:1214-1215.
10. Dorovini-Zis K, Zis AP (1991): Innervation of the zona fasciculata of the adult human adrenal cortex: a light and electron microscopic study. J Neural Transm 84:75-84.
11. Engeland WC, Dallman MF (1975): Compensatory adrenal growth is neurally mediated. Neuroendocrinology 19: 352-362.
12. Fang VS, Jiang HK, Lu RB, Rose RP, Luchins DJ (1988): Cortisol response to ACTH infusion in depressed patients: Comparison with age-, sex-, and weight-matched normal subjects. Psychoneuroendocrinology 13:497-503.
13. Gold PW, Chrousos G, Kellner C, Post R, Roy A, Augerinos P, Schulte H, Oldfield E, Loriaux DL (1984): Psychiatric implications of basic and clinical studies with corticotropin-releasing factor. Am J Psychiatry 141:619-627.
14. Gold PW, Loriaux DL, Roy A, Kling MA, Calabrese JR, Kellner CH, Nienian LK, Post RM, Pickar D, Gallucci W, Avgerinos P, Paul S, Oldfield EH, Cutler GB, Chrousos GP (1986): Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. Pathophysiologic and diagnostic implications. N Engl J Med 314:1329-1335.
15. Graybeal ML, Fang VS (1985): Physiological dosing of exogenous ACTH. Acta Endocrinol 108:401-406.
16. Hamilton M (1967): Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 6:278-296.
17. Holsboer F, Müller OA, Doerr HG, Sippell WG, Stalla GK, Müller OA (1984): ACTH and multisteroid responses to corticotropin-releasing factor in depressive illness: Relationship to multisteroid responses after ACTH stimulation and dexamethasone suppression. Psychoneuroendocrinology 9: 147-160.
18. Hornsby PJ (1985): The regulation of adrenocortical function by control of growth and structure. In Anderson DC, Winter JSD (eds.), Adrenal Cortex. London: Butterworths, pp 1-31.
19. Hunter WM, Greenwood FC (1962): Preparation of iodine-131 labeled human growth hormone of high specific activity. Nature 194:495-496.
20. Krishnan KR, Ritchie JC, Saunders WB, Nemeroff CB, Carroll BJ (1990): Adrenocortical sensitivity to low-dose ACTH administration in depressed patients. Biol Psychiatry 27:930-933.
21. Maas JW, Katz MM, Koslow SH, Swann A, Davis JM, Berman N, Bowden CL, Stokes PE, Landis H (1994): Adrenomedullary function in depressed patients. J Psychiatr Res 28:357-367.
22. Markowska A, Nussdorfer GG, Malendowicz LK (1994): Proliferogenic effect of neurotensin (NT) and neuromedin-N (NMN) on the rat adrenal cortex: Evidence that angiotensin-II mediates the effect of NMN, but not of NT. Neuropeptides 27:91-94.
23. Nemeroff CB, Krishnan KRR, Reed D, Leder R, Beam C, Dunnick NR (1992): Adrenal gland enlargement in major depression: A computed tomographic study. Arch Gen Psychiatry 49:384-387.
24. Nicholson WE, Davis DR, Sherrell BJ, Orth DN (1984): Rapid radioimmunoassay for corticotropin in unextracted human plasma. Clin Chem 30:259-265.
25. Orth DN, Kovacs WJ, DeBold CR (1992): The adrenal cortex. In Wilson JD, Foster DW (eds), Williams Textbook of Endocrinology, 8th edition. Philadelphia: W.B. Saunders, pp 489-619.
26. Raff H, Findling JW (1989): New immunoradiometric assay of corticotropin evaluated in normal subjects and patients with Cushing's syndrome. Clin Chem 35:596-600.
27. Raff H, Findling JW, Wong J (1989): Short loop adrenocorticotropin (ACTH) feedback after ACTH-(1-24) injection in man is an artifact of the immunoradiometric assay. J Clin Endocrinol Metab 69:678-680.
28. Rao AJ, Long JA, Ramachandran J (1978): Effects of antiserum to adrenocorticotropin on adrenal growth and function. Endocrinology 102:371-378.
29. Rhoades HM, Overall JE (1983): The Hamilton Depression Scale: Factor scoring and profile classification. Psychopharmacol Bull 19:91-96.
30. Rubin RT (1989): Pharmacoendocrinology of major depression. Eur Arch Psychiatr Neurol Sci 238:259-267.
31. Rubin RT, Phillips JJ (1991): Adrenal gland volume determination by computed tomography and magnetic resonance imaging in normal subjects. Invest Radiol 26:465-469.
32. Rubin RT, Phillips JJ (1993): Adrenal gland volume in major depressives (letter to editor). Arch Gen Psychiatry 50:833-834.
33. Rubin RT, Gouin PR, Poland RE (1973): Biogenic amine metabolism and neuroendocrine function in affective disorders. In de la Fuente R, Weisman MN (eds), Psychiatry: Proceedings of the V World Congress of Psychiatry. Princeton, NJ: Excerpta Medica, pp 1036-1039.
34. Rubin RT, Poland RE, Lesser IM, Winston RA, Blodgett ALN (1987): Neuroendocrine aspects of primary endogenous depression I: Cortisol secretory dynamics in patients and matched control subjects. Arch Gen Psychiatry 44:329-336.
35. Rubin RT, Phillips JJ, Sadow TF, McCracken JT (1995): Adrenal gland volume in major depression: increase during the depressive episode and decrease with successful treatment. Arch Gen Psychiatry 52:213-218.
36. Sachar EJ, Hellman L, Roffwarg HP, Halpern FS, Fukushima DK, Gallagher TF (1973): Disrupted 24-hour patterns of cortisol secretion in psychotic depression. Arch Gen Psychiatry 28:19-24.
37. Spitzer RL, Williams JBW, Gibbon M, First MB (1990): Structured Clinical Interview for DSM-IH-R. Washington, DC: American Psychiatric Press.
38. Stalla GK, Stalla J, Schopohl J, von Werder K, Müller OA (1986): Corticotropin-releasing factor in humans. I. CRF stimulation in normals and CRF radioimmunoassay. Horm Res 24:229-245.
39. Stein E, McCrank E, Schaeffer B, Goyer R (1993): Adrenal gland weight and suicide. Can J Psychiatry 38:563-566.
40. Szigethy E, Conwell Y, Forbes NT, Cox C, Caine ED (1994): Adrenal weight and morphology in victims of completed suicide. Biol Psychiatry 36:374-380.
41. Thompson LM, Rubin RT, McCracken JT (1992): Neuroendocrine aspects of primary endogenous depression XII. Receiver operating characteristic and kappa analyses of serum and urine cortisol measures in patients and matched controls. Psychoneuroendocrinology 17:507-515.
42. von Bardeleben U, Holsboer F (1988): Human corticotropin releasing hormone: Clinical studies in patients with affective disorders, alcoholism, panic disorder and in normal controls. Prog Neuropsychopharmacol Biol Psychiatry 12:S165-S187.