Repeated analysis of sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes: Effect of glutathione S-transferase T1 and M1 genotype

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 351, Issue 1, 1996, Pages 79-85

  Landi, Stefano ^a,c   Ponzanelli, Isabella ^a   Hirvonen, Ari ^b   Norppa, Hannu ^b   Barale, Roberto ^a  

^a UNIVERSITY OF PISA   (Italy)

^b FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^c Dpt Sci Ambiente e del Territorio   (Italy)

Author keywords

Diepoxybutane; Individual sensitivity; Repeated measurement; Sister chromatid exchange

Indexed keywords

BUTADIENE DIEPOXIDE; GLUTATHIONE TRANSFERASE;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENOTOXICITY; GENOTYPE; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; MALE; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE;

EID: 0029983811     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(95)00215-4     Document Type: Article

References (31)

1. Al Saadi, A., Palutke, M., and Kumar, G.K. (1980) Evolution of chromosomal abnormalities in sequential cytogenetic studies of ataxia telangiectasia. Hum. Genet., 55, 23-29.
2. Auerbach, A.D. and Wolman, S.R. (1979) Carcinogen-induced chromosome breakage in chromosome instability syndromes. Cancer Genet. Cytogenet., 1, 21-28.
3. Cohen, M.M., Shaham, M., Dagan, J., Shmueli, E. and Kohn, G. (1975) Cytogenetic Investigatons in families with ataxiatelangiectasia. Cytogenet. Cell Genet., 15, 338-356.
4. Cohen, M.M. and Levy H. (1989) Chromosome instability syndromes, in H. Harris and K. Hirschhorn (Eds,), Advances in Human Genetics, Vol. 18, Plenum Press. New York, pp. 43-149.
5. Dallapiccola, B., Porfirio, B., Mokini, V., Alimena, G., Isacchi, G. and Gandini, E. (1985) Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes. Hum. Genet., 69, 62-65.
6. Dabholkar, M., Bostick-Bruton, F., Weber, C., Egwuagu, C., Bohr, V.A. and Reed, E. (1993) Expression of excision repair genes in non-malignant bone marrow from cancer patients. Mutation Res., 293, 151-160.
7. Daly, A.K., Cholerton, S., Gregory, W. and Idle, J.R. (1993) Metabolic polymorphisms. Pharmacol. Ther., 57, 129-160.
8. Ejima, Y. and Sasaki, M.S. (1986) Enhanced expression of X-ray and UV-induced chromosome aberrations by cytosine arabinoside in ataxia-telangiectasia cells. Mutation Res., 159, 117-123.
9. Fryer, A.A., Zhao, L., Alldersea, J., Pearson, W.R. and Strange, R.C. (1993) Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null genotype. Biochem. J., 295, 313-315.
10. Gebhart, E., Kysela, D., Matthee, H. and Nikol, M. (1985) Cytogenetic analyses utilizing various clastogens in two sibs with Fanconi anemia, their relatives and control individuals. Hum. Genet., 69, 309-315.
11. Hallier, E., Langhof, T., Dannappel, D., Leutbecher, M., Schroeder, K., Goergens, H.W., Muller, A. and Bolt, H. (1993) Polymorphism of glutathione conjugation of methylbromide, ethylene oxide and dichloromethane in human blood: influence of the induction of sister chromatid exchange (SCEs) in lymphocytes. Arch. Toxicol., 67, 173-178.
12. Heagerty, A.H.M., Fitzgerald, D., Snith, A., Bowers, B., Jones, P., Fryer, A.A., Zhao, L., Alldersea, J. and Strange, R.C. (1994) Glutathione 5-transferase GSTM1 phenotypes and protection against cutaneous malignancy. Lancet, 343, 266-268.
13. Kohn, P.H., Whang-Peng, J. and Levis, W.R. (1982) Chromosomal instability in ataxia-telangiectasia. Cancer Genet. Cytogenet., 6, 289-302
14. Kuhn, E.M. (1978) Mitotic chiasmata and other quadriradials in mitomycin-C treated Bloom's syndrome lymphocytes. Chromosoma, 66, 287-297.
15. Norppa, H., Hirvonen, A., Jarvetnaus, H., Uuskula, M., Tasa, G., Ojajarvi, A. and Sorsa, M. (1995) Role of GSTT1 and GSTM1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes. Carcinogenesis, 16, 1261-1264.
16. Pemble, S., Schroeder, K.R., Spencer, S.R., Meyer, D.J., Hallier, E., Bolt, H.M., Ketterer, B. and Taylor, J.B. (1994) Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem. J., 300, 271-276.
17. Perry, P. and Wolff, S. (1974) New Giemsa method for the differential staining of sister chromatids. Nature, 251, 156-158.
18. Savage, J.R.K. and Reddy, K.S. (1987) On the localization of mitomycin C-induced aberrations in normal human and Fanconi's anaemia cells. Mutation Res., 178, 65-71.
19. Schwartz, S., Astemborski, J.A., Budacz, A.P., Boughman, J.A., Wasserman, S.S. and Cohen, M.M. (1990) Repeated measurement of spontaneous and clastogen-induced sister chromatid exchanges. Mutation Res., 234, 51-59.
20. Shirashi, Y. and Sandberg, A.A. (1979) Effect of chemicals on the frequency of sister chromatid exchanges and chromosome aberrations in normal and Bloom's syndrome lymphocytes. Cytobios, 26, 97-108.
21. Swift, M.R., Sholman, L., Perry, M. and Chase, C. (1976) Malignant neoplasm in the families of patients with Ataxia telangiectasia. Cancer Res., 36, 209-215.
22. Swift, M.R., Caldwell, R.J. and Chase, C. (1980) Reassessment of cancer predisposition of Fanconi Anemia heterozygotes. J. Natl. Cancer. Inst., 65, 863-867.
23. Swift, M.R., Reitnauer, P.J., Morrell, D. and Chase, C.L. (1987) Breast and other cancers in families with Ataxia telangiectasia. N. Eng. J. Med., 316, 1289-1294.
24. Swift, M.R., Morrell, D., Massey, R. and Chase, C.L. (1991) Cancer incidence in 161 ataxia telangiectasia families studied prospectively. New Engl. J. Med., 326, 1831-1836.
25. Uusküla, M., Järventaus, H., Hirvonen, A., Sorsa, M. and Norppa, H. (1995) Influence of GSTM1 genotype on sister chromatid exchange induction by styrene-7,8-oxide and 1.2-epoxy-3-butene in cultured human lymphocytes. Carcinogenesis, 16, 947-950.
26. van Poppel, G., de Vogel, N., van Balderen, P.J., Kok, F.J. (1992) Increased cytogenetic damage in smokers deficient in glutathione S-transferase isozyme μ. Carcinogenesis, 13, 303-305.
27. Verma, R.S. and Babu, A. (1989) Human chromosomes. Manual of Basic Techniques. Pcrgamon press, New York.
28. Wiencke, J.K., Kelsey, K.T., Lamela, R.A. and Toscano Jr., W.A. (1990) Human glutathione S-transferase deficiency as a marker of susceptibility to epoxide-induced cytogenetic damage. Cancer Res., 50, 1585-1590.
29. Wiencke, J.K., Christiani, D.C. and Kelsey, K.T. (1991) Bimodal distribution of sensitivity to SCE induction by diepoxybutane in human lymphocytes. I. Correlation with chromosomal aberrations. Mutation Res., 248, 17-26.
30. Wiencke, J.K. and Kelsey, K.T. (1993) Susceptibility to induction of chromosomal damage by metabolites of 1,3-butadiene and its relationship to spontaneous sister chromatid exchange frequencies in human lymphocytes, in: M. Sorsa, K. Peltonen, H. Vainio and K. Hemminki (Eds.), Butadiene and Styrene: Assessment of Health Hazards. IARC Scientific Publications No. 127, IARC, Lyon, 265-273.
31. Wiencke, J.K., Pemble, S., Ketterer, B. and Kelsey, K.T. (1995) Gene deletion of glutathione S-transferase theta: correlation with induced genetic damage and potential role in endogenous mutagenesis. Cancer Epidemiol. Biomarkers Prevent., 4, 253-259.