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Volumn 24, Issue 4, 1996, Pages 390-394

Excretion and identification of methacrylonitrile metabolites in the bile of male F344 rats

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; GLUTATHIONE; METHACRYLONITRILE; PHENOBARBITAL; PROADIFEN;

EID: 0029983780     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (14)
  • 1
    • 0026099218 scopus 로고
    • Toxicology of methacrylonitrile
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    • Farooqui, M.Y.H.1    Mumtaz, M.M.2
  • 2
    • 0019825946 scopus 로고
    • In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione and irreversible binding to proteins and nucleic acids
    • F. P. Guengerich, L. E. Geiger, L. L. Hogy, and P. L. Wright: In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione and irreversible binding to proteins and nucleic acids. Cancer Res. 41, 4925-4933 (1981).
    • (1981) Cancer Res. , vol.41 , pp. 4925-4933
    • Guengerich, F.P.1    Geiger, L.E.2    Hogy, L.L.3    Wright, P.L.4
  • 3
    • 0019199109 scopus 로고
    • Metabolism of acrylonitrile to cyanide in vitro studies
    • M. E. Abreu and A. E. Ahmed: Metabolism of acrylonitrile to cyanide in vitro studies. Drug Metab. Dispos. 8, 376-379 (1980).
    • (1980) Drug Metab. Dispos. , vol.8 , pp. 376-379
    • Abreu, M.E.1    Ahmed, A.E.2
  • 4
    • 0022000828 scopus 로고
    • Acrylonitrile-induced gastric lesions: Role of gastric glutathione
    • B. I. Ghanayem, P. J. Boor, and A. E. Ahmed: Acrylonitrile-induced gastric lesions: Role of gastric glutathione. J. Pharmacol. Exp. Ther. 232, 570-577 (1985).
    • (1985) J. Pharmacol. Exp. Ther. , vol.232 , pp. 570-577
    • Ghanayem, B.I.1    Boor, P.J.2    Ahmed, A.E.3
  • 5
    • 0023731834 scopus 로고
    • Mutagenicity of acrylonitrile and its metabolite 2-cyanoethylene oxide in human lymphoblasts in vitro
    • L. Recio and T. R. Skopec: Mutagenicity of acrylonitrile and its metabolite 2-cyanoethylene oxide in human lymphoblasts in vitro. Mutat. Res. 206, 297-305 (1988).
    • (1988) Mutat. Res. , vol.206 , pp. 297-305
    • Recio, L.1    Skopec, T.R.2
  • 6
    • 0028046087 scopus 로고
    • Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats
    • L. T. Burka, M. I. Sanchez, A. E. Ahmed, and B. I. Ghanayem: Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats. Arch. Toxicol. 68, 611-618 (1994).
    • (1994) Arch. Toxicol. , vol.68 , pp. 611-618
    • Burka, L.T.1    Sanchez, M.I.2    Ahmed, A.E.3    Ghanayem, B.I.4
  • 7
    • 0028363335 scopus 로고
    • Investigation of the metabolic basis for the differences in methacrylonitrile acute toxicity in rats and mice
    • B. I. Ghanayem, M. I. Sanchez, and L. T. Burka: Investigation of the metabolic basis for the differences in methacrylonitrile acute toxicity in rats and mice. J. Pharmacol. Exp. Ther. 269, 581-588 (1994).
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 581-588
    • Ghanayem, B.I.1    Sanchez, M.I.2    Burka, L.T.3
  • 8
    • 0026739479 scopus 로고
    • Effects of dose, strain and dosing vehicle on methacrylonitrile disposition in rats and identification of a novel exhaled metabolite
    • B. I. Ghanayem, M. I. Sanchez, and L. T. Burka: Effects of dose, strain and dosing vehicle on methacrylonitrile disposition in rats and identification of a novel exhaled metabolite. Drug Metab. Dispos. 20, 643-652 (1992).
    • (1992) Drug Metab. Dispos. , vol.20 , pp. 643-652
    • Ghanayem, B.I.1    Sanchez, M.I.2    Burka, L.T.3
  • 9
    • 0021262884 scopus 로고
    • Studies on the mechanism of acute toxicity of nitriles in mice
    • H. Tanii and K. Hashimoto: Studies on the mechanism of acute toxicity of nitriles in mice. Arch. Toxicol. 55, 47-54 (1984).
    • (1984) Arch. Toxicol. , vol.55 , pp. 47-54
    • Tanii, H.1    Hashimoto, K.2
  • 10
    • 0026604418 scopus 로고
    • Methacrylonitrile: In vivo metabolism to cyanide in rats, mice, and gerbils
    • M. Y. H. Farooqui, R. G. Diaz, and J. H. Deleon: Methacrylonitrile: In vivo metabolism to cyanide in rats, mice, and gerbils. Drug Metab. Dispos. 20, 156-160 (1992).
    • (1992) Drug Metab. Dispos. , vol.20 , pp. 156-160
    • Farooqui, M.Y.H.1    Diaz, R.G.2    Deleon, J.H.3
  • 12
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    • (NIH Publication No. 86-23.) NIH, Bethesda, MD
    • US Department of Health and Human Services, National Institutes of Health: "Guide to the Care and Use of Laboratory Animals." (NIH Publication No. 86-23.) NIH, Bethesda, MD 1985.
    • (1985) Guide to the Care and Use of Laboratory Animals
  • 13
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    • Metabolism of methacrylonitrile to cyanide: In vitro studies
    • M. Y. H. Farooqui, R. G. Diaz, and R. J. Cavazos: Metabolism of methacrylonitrile to cyanide: In vitro studies. J. Biochem. Toxicol. 5, 109-114 (1990).
    • (1990) J. Biochem. Toxicol. , vol.5 , pp. 109-114
    • Farooqui, M.Y.H.1    Diaz, R.G.2    Cavazos, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.