Upregulation of B50/GAP-43 protein mRNA in rat dorsal root ganglia during cisplatin intoxication

Journal of Neuroscience Research

Volumn 44, Issue 2, 1996, Pages 142-148

  Hamers, F P T ^a,b   Plantinga, L C ^a   Verhaagen, J ^a,c   Neijt, J P ^a   Gispen, W H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

B50 GAP 43; cisplatin neurotoxicity; in situ hybridization; ORG 2766

Indexed keywords

2 AMINO 4 (METHYLSULFONYL)BUTYRYLGLUTAMYLHISTIDYLPHENYLALANYL DEXTRO LYSYLPHENYLALANINE; CISPLATIN; CORTICOTROPIN DERIVATIVE; CORTICOTROPIN[4-9]; NEUROMODULIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IN SITU HYBRIDIZATION; INTOXICATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SPINAL GANGLION; SUBCUTANEOUS DRUG ADMINISTRATION;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; CISPLATIN; GANGLIA, SPINAL; GAP-43 PROTEIN; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; MALE; MEMBRANE GLYCOPROTEINS; NERVE REGENERATION; NERVE TISSUE PROTEINS; NEUROFILAMENT PROTEINS; NEURONS; NEURONS, AFFERENT; NEUROTOXINS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0029983742     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19960415)44:2<142::AID-JNR6>3.0.CO;2-D     Document Type: Article

References (39)

1. Apfel SC, Lipton RB, Arezzo JC, Kessler JA (1991): Nerve growth factor prevents toxic neuropathy in mice. Ann Neurol 29,87-90.
2. Bär PRD, Schrama LH, Gispen WH (1990): Neurotrophic effects of the ACTH/MSH-like peptides in the peripheral nervous system. In De Wied D (ed): "Neuropeptide Concept." Amserdam: Elsevier Science Publishers BV, pp 175-211.
3. Basi GS, Jacobson RD, Virag I, Schilling J, Skene JHP (1987): Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. Cell 49:785-791.
4. Bisby MA, Redshaw JD (1987): Acrylamide neuropathy: Changes in the composition of proteins of fast axonal transport resemble those observed in regenerating axons. J Neurochem 48:924-928.
5. Chong MS, Reynolds ML, Irwin N, Coggeshall RE, Emson PC, Benowitz LI (1994): GAP-43 expression in primary sensory neurons following central axotomy. J Neurosci 14:4375-4384.
6. Corda Y, Anin MA, Leng M, Job D (1992): RNA polymerases react differently at d(ApG) and d(GpG) adducts in DNA modified by cis-diamminedichloroplatinum(IT). Biochemistry 31:1904-1908.
7. Curtis R, Stewart HJS, Hall SM, Wilkin GP, Mirsky R, Jessen KR (1992): GAP-43 is expressed by nonmyelin-forming Schwann cells of the peripheral nervous system. J Cell Biol 116:1455-1464.
8. De Koning P, Neijt JP, Jennekens FGI, Gispen WH (1987): Evaluation of cis-diamminedichloroplatinum(II) (cisplatin) neurotoxicity in rats. Toxicol Appl Pharmacol 89:81-87.
9. De Koning P, Neijt JP, Jennekens FGI, Gispen WH (1988): ORG 2766 protects from cisplatin-induced neurotoxicity in rats. Exp Neurol 97:746-750.
10. Dyer JK, Philipsen HLA, Tonnaer JADM, Hermkens PHH, Haynes LW (1995): Melanocortin analogue Org2766 binds to rat Schwann cells, upregulates NGF low-affinity receptor p75, and releases neurotrophic activity. Peptides 16:515-522.
11. Elderson A, Gerritsen van der Hoop R, Haanstra W, Neijt JP, Gispen WH, Jennekens FGI (1989): Vibration perception and thermoperception as quantitative measurements in the monitoring of cisplatin-induced neurotoxicity. J Neurol Sci 93:167-174.
12. Gerritsen van der Hoop R, De Koning P, Boven E, Neijt JP, Jennekens FGI, Gispen WH (1988): Efficacy of the neuropeptide ORG 2766 in the prevention and treatment of cisplatin-induced neurotoxicity in rats. Eur J Cancer 24:637-642.
13. Gerritsen van der Hoop R, Van Houwelingen JC, Van der Burg MEL, Ten Bokkel Huinink WW, Neijt JP (1990): The incidence of neuropathy in 395 ovarian cancer patients treated with or without cisplatin. Cancer 66:1697-1702.
14. Gerritsen van der Hoop R, Hamers FPT, Neijt JP, Veldman H, Gispen WH, Jennekens FGI (1994): Protection against cisplatin induced neurotoxicity by ORG 2766: histological and electrophysiological evidence. J Neurol Sci 126:109-115.
15. Gispen WH (1990): Therapeutic potential for melanocortins in peripheral nerve disease. Trends Pharmacol Sci 11:221-222.
16. Hamers FPT, Gerritsen van der Hoop R, Steerenburg PA, Neijt JP, Gispen WH (1991a): Putative neurotrophic factors in the protection of cisplatin-induced peripheral neuropathy in rats. Toxicol Appl Pharmacol 111:514-522.
17. Hamers FPT, Gispen WH, Neijt JP (1991b): Neurotoxic side-effects of cisplatin. Eur J Cancer 27:372-376.
18. Hamers FPT, Pette C, Bravenboer B, Vecht CJ, Neijt JP, Gispen WH (1993): Cisplatin-induced neuropathy in mature rats: Effects of the melanocortin-like peptide ORG 2766. Cancer Chemother Pharmacol 32:162-166.
19. Hoi EM, Mandys V, Sodaar P, Gispen WH, Bär PRD (1994): Protection by an ACTH4-9 analogue against the toxic effects of cisplatin and taxol on sensory neurons and glial cells in vitro. J Neurosci Res 39:178-185.
20. Neve RL, Perrone-Bizzozero NI, Finklestein S, Zwiers H, Bird E, Kurnit DM, Benowitz LI (1987): The neuronal growth-associated protein GAP 43 (B-50, F1): Neuronal specificity, developmental regulation and regional distribution of the human and rat mRNA. Mol Brain Res 2:177-183.
21. Oestreicher AB, Dekker LV, Gispen WH (1986): A radioimmunoassay for the phosphoprotein B-50: Distribution in rat brain. J Neurochem 46:1366-1369.
22. Plantinga LC, Verhaagen J, Edwards PM, Hoi EM, Bär PRD, Gispen WH (1993): The expression of B-50/GAP-43 in Schwann cells is upregulated in degenerating peripheral nerve stumps following nerve injury. Brain Res 602:69-76.
23. Richardson PM, Verge VMK, Riopelle RJ (1989): Quantitative radio-autography for NGF receptors. In Rush RA (ed): "Nerve Growth Factors." Chichester: John Wiley & Sons, Ltd., pp 315-326.
24. Skene JHP (1989): Axonal growth-associated proteins. Annu Rev Neurosci 12:127-156.
25. Skene JHP, Willard M (1981): Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems. J Cell Biol 89:96-103.
26. Strand FL, Rose KJ, King JA, Segarra AC, Zuccarelli LA (1989): ACTH modulation of nerve development and regeneration. Prog Neurobiol 33:45-85.
27. Thompson SW, Davis LE, Kornfeld M, Hilgers RD, Standefer JC (1984): Cisplatin neuropathy. Cancer 54:1269-1275.
28. Van der Zee CEEM, Nielander H, Vos JP, Lopes da Silva S, Verhaagen J, Oestreicher AB, Schrama LH, Schotman P, Gispen WH (1989): Expression of growth associated protein B-50 (GAP-43) in dorsal root ganglia and sciatic nerve during regenerative sprouting. J Neurosci 10:3505-3512.
29. Verge VMK, Tetzlaff W, Richardson PM, Bisby MA (1990): Correlation between GAP43 and nerve growth factor receptors in rat sensory neurons. J Neurosci 10:926-934.
30. Verhaagen J, Van Hooff COM, Edwards PM, De Graan PNE, Oestreicher AB, Schotman P, Jennekens FGI, Gispen WH (1986): The kinase C substrate protein B-50 and axonal regeneration. Brain Res Bull 17:737-741.
31. Verhaagen J, Edwards PM, Jennekens FGI, Schotman P, Gispen WH (1987): Early effects of an ACTH(4-9) analog (Org 2766) on regenerative sprouting demonstrated by the use of neurofilament binding antibodies isolated from a serum raised by α-MSH immunization. Brain Res 404:142-150.
32. Verhaagen J, Oestreicher AB, Gispen WH, Margolis FL (1989): The expression of the growth associated protein B-50/GAP43 in the olfactory system of neonatal and adult rats. J Neurosci 9:683-691.
33. Verhaagen J, Greer CA, Margolis FL (1990a): B-50/GAP43 gene expression in the rat olfactory system during postnatal development and aging. Eur J Neurosci 2:397-407.
34. Verhaagen J, Oestreicher AB, Grillo M, Khew-Goodall Y-S, Gispen WH, Margolis FL (1990b): Neuroplasticity in the olfactory system: Differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B-50/ GAP-43 and the olfactory marker protein. J Neurosci Res 26:31-44.
35. Verhaagen J, Zhang Y, Hamers FPT, Gispen WH (1993): Elevated expression of B-50 (GAP-43)-mRNA in a subpopulation of olfactory bulb mitral cells following axotomy. J Neurosci Res 35:162-169.
36. Windebank AJ, Smith AG, Russell JW (1994): The effect of nerve growth factor, ciliary neurotrophic factor, and ACTH analogs on cisplatin neurotoxicity in vitro. Neurology 44:488-494.
37. Woolf CJ, Reynolds ML, Molander C, O'Brien C, Lindsay RM, Benowitz LI (1990): The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury. Neuroscience 34:465-478.
38. Yankner BA, Benowitz LI, Villa Komaroff L, Neve RL (1990): Transfection of PC12 cells with the human GAP-43 gene: Effects on neuriteoutgrowth and regeneration. Brain Res Mol Brain Res 7:39-44.
39. Zwiers H, Veldhuis HD, Schotman P, Gispen WH (1976): ACTH. cyclic nucleotides, and brain protein phosphorylation in vitro. Neurochem Res 1:669-677.