Unitary excitatory synaptic currents in preganglionic neurons mediated by two distinct groups of interneurons in neonatal rat sacral parasympathetic nucleus

Journal of Neurophysiology

Volumn 76, Issue 1, 1996, Pages 215-226

  Araki, Isao ^a   De Groat, William C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; BICUCULLINE; GLYCINE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; STRYCHNINE;

ANIMAL CELL; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLADDER FUNCTION; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; INTERNEURON; LUMBOSACRAL SPINE; MICTURITION; NEWBORN; NONHUMAN; PARASYMPATHETIC NERVE; PRIORITY JOURNAL; RAT; SACRAL SPINAL CORD; SYNAPTIC TRANSMISSION;

EID: 0029982689     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1996.76.1.215     Document Type: Article

References (42)

1. ANDERSON, C. R. AND EDWARDS, S. L. Intraperitoneal injections of Fluorogold reliably labels all sympathetic preganglionic neurons in the rat. J. Neurosci. Methods 53: 137-141, 1994.
2. ARAKI, I. Inhibitory postsynaptic currents and the effects of GABA on visually identified sacral parasympathetic preganglionic neurons in neonatal rats. J. Neurophysiol. 72: 2903-2910, 1994.
3. ARAKI, I. AND DE GROAT, W. C. Patch clamp and morphological analysis of synaptic transmission in the lumbosacral parasympathetic nucleus (SPN) of neonatal rats. Soc. Neurosci. Abstr. 20: 115, 1994.
4. BEKKERS, J. M. AND STEVENS, C. F. NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus. Nature Lond 341: 230-233, 1989.
5. BIRDER, L. A. AND DE GROAT, W. C. Induction of c-fos gene expression of spinal neurons in the rat by nociceptive and non-nociceptive stimulation of the lower urinary tract. Am. J. Physiol. 265 (Regulatory Integrative Comp. Physiol. 34): R326-R333, 1992.
6. BLANKENSHIP, J. E. AND KUNO, M. Analysis of spontaneous subthreshold activity in spinal motoneuron of the cat. J. Neurophysiol. 31: 195-209, 1968.
7. CABOT, J. B., ALESSI, V., CARROLL, J., AND LIGORIO, M. Spinal cord lamina V and lamina VII interneuronal projections to sympathetic preganglionic neurons. J. Comp. Neurol. 347: 515-530, 1994.
8. COLLINGRIDGE, G. L., HERRON, C. E., AND LESTER, R. A. J. Frequency-dependent N-methyl-D-aspartate receptor-mediated synaptic transmission in rat hippocampus. J. Physiol. Lond. 399: 301-312, 1988.
9. DE GROAT, W. C., BOOTH, A. M., MILNE, R. J., AND ROPPOLO, J. R. Parasympathetic preganglionic neurons in the sacral spinal cord. J. Auton. Nerv. Syst. 5: 23-43, 1982.
10. DE GROAT, W. C., NADELHAFT, I., MILNE, R. J., BOOTH, A. M., MORGAN, C., AND THOR, K. Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine. J. Auton. Nerv. Syst. 3: 135-160, 1981.
11. DE GROAT, W. C., ROPPOLO, J. R., YOSHIMURA, N., AND SUGAYA, K. Neural control of the urinary bladder and colon. In: Innervation of the Gut: Pathophysiological Implications, edited by Y. Tache, D. L. Wingate, and T. F. Burks. Boca Raton, FL: CRC, 1994, p. 167-190.
12. DE GROAT, W. C. AND RYALL, R. W. Recurrent inhibition in sacral parasympathetic pathways to the bladder. J. Physiol. Lond. 196: 579-591, 1968.
13. DINGLEDINE, R., HYNES, M. A., AND KING, G. L. Involvement of N-methyl-D-aspartate receptors in epileptiform bursting in the rat hippocampal slice. J. Physiol. Lond. 380: 175-189, 1986.
14. DUN, N. J. AND Mo, N. Inhibitory postsynaptic potentials in neonatal rat sympathetic preganglionic neurones in vitro. J. Physiol. Lond. 410: 267-281, 1989.
15. EDWARDS, F. A., KONNERTH, A., SAKMANN, B., AND TAKAHASHI, T. A thin slice preparation for patch clamp recordings from neurons of the mammalian central nervous system. Pfluegers Arch. 414: 600-612, 1989.
16. HESTRIN, S., NICOLL, R. A., PERKEL, D. J., AND SAH, P. Analysis of excitatory synaptic action in pyramidal cells using whole-cell recording from rat hippocampal slices. J. Physiol. Lond. 422: 203-225, 1990.
17. JONAS, P., MAJOR, G., AND SAKMANN, B. Quantal components of unitary EPSCs at the mossy fibre synapse on CA3 pyramidal cells of rat hippocampus. J. Physiol. Lond. 472: 615-663, 1993.
18. KAY, A. R., MILES, R., AND WONG, K. S. Intracellular fluoride alters the kinetic properties of calcium currents facilitating the investigation of synaptic events in hippocampal neurons. J. Neurosci. 6: 2915-2920, 1986.
19. KELLER, B. U., KONNERTH, A., AND YAARI, Y. Patch clamp analysis of excitatory synaptic currents in granule cells of rat hippocampus. J. Physiol. Lond. 435: 275-293, 1991.
20. KONNERTH, A., LLANO, I., AND ARMSTRONG, C. M. Synaptic currents in cerebellar Purkinje cells. Proc. Natl. Acad. Sci. USA 87: 2662-2665, 1990.
21. KUNO, M. Quantal aspects of central and ganglionic synaptic transmission in vertebrates. Physiol. Rev. 51: 647-678, 1971.
22. KUNO, M. AND WEAKLY, J. N. Facilitation of monosynaptic excitatory synaptic potentials in spinal motoneurones evoked by internuncial impulses. J. Physiol. Lond. 224: 271-286, 1972.
23. MALLORY, B., STEERS, W. D., AND DE GROAT, W. C. Electrophysiological study of micturition reflexes in rats. Am. J. Physiol. 257 (Regulatory Integrative Comp. Physiol. 26): R410-R421, 1989.
24. MANABE, T., ARAKI, I., TAKAHASHI, T., AND KUNO, M. Membrane currents recorded from sexually dimorphic motoneurones of the bulbocavernosus muscle in neonatal rats. J. Physiol. Lond. 440: 419-435, 1991.
25. MARSON, L., PLATT, K. B., AND MCKENNA, K. E. Central nervous system innervation of the penis as revealed by the transneuronal transport of pseudorabies virus. Neuroscience 55: 263-280, 1993.
26. MCKENNA, K. E. AND NADELHAFT, I. The organization of the pudendal nerve in the male and female rat. J. Comp. Neurol. 248: 532-549, 1986.
27. MCMAHON, S. B. AND MORRISON, J. F. B. Two groups of spinal interneurones that respond to stimulation of the abdominal viscera of the cat. J. Physiol. Lond. 322: 21-34, 1982.
28. MORI, A., TAKAHASHI, T., MIYASHITA, Y., AND KASAI, H. Two distinct glutamatergic synaptic inputs to striatal medium spiny neurones of neonatal rats and paired-pulse depression. J. Physiol. Lond. 476: 217-228, 1994.
29. NADELHAFT, I. AND BOOTH, A. M. The location and morphology of preganglionic neurones and the distribution of visceral afferents from the rat pelvic nerve: a horseradish peroxidase study. J. Comp. Neurol. 226: 238-245, 1984.
30. NADELHAFT, I., VERA, P. L., CARD, J. P., AND MISELIS, R. R. Central nervous system neurons labelled following the injection of pseudorabies virus into the rat urinary bladder. Neurosci. Lett. 143: 271-274, 1992.
31. NICOLL, R. A., MALENKA, R. C., AND KAUER, J. A. Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system. Physiol. Rev. 70: 513-565, 1990.
32. PAULSEN, O. AND HEGGELUND, P. The quantal size at retinogeniculate synapses determined from spontaneous and evoked EPSCs in guinea-pig thalamic slices. J. Physiol. Lond. 480: 505-511, 1994.
33. SILVER, R. A., TRAYNELIS, S. F., AND CULL-CANDY, S. G. Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature Lond. 355: 163-166, 1992.
34. STEERS, W. D., CIAMBOTTI, J., ETZEL, B., ERDMAN, S., AND DE GROAT, W. C. Alterations in afferent pathways from the urinary bladder of the rat in response to partial urethral obstruction. J. Comp. Neurol. 310: 401-410, 1991.
35. STERN, P., EDWARD, F. A., AND SAKMANN, B. Fast and slow components of unitary EPSCs on stellate cells elicited by focal stimulation in slices of rat visual cortex. J. Physiol. Lond. 449: 247-278, 1992.
36. SUGAYA, K. AND DE GROAT, W. C. Effects of MK-801 and CNQX, glutamate receptor antagonists, on bladder activity in neonatal rats. Brain Res. 640: 1-10, 1994.
37. TAKAHASHI, T. The minimal inhibitory synaptic currents evoked in neonatal rat motoneurones. J. Physiol. Lond. 450: 593-611, 1992.
38. VIZZARD, M. A., ERICKSON, V. L., CARD, J. P., ROPPOLO, J. R., AND DE GROAT, W. C. Transneuronal labeling of neurons in the adult rat brainstem and spinal cord after injection of pseudorabies virus into the urethra. J. Comp. Neurol. 355: 629-640, 1995.
39. WHITE, L. E., HODGES, H. D., CARNES, K. M., PRICE, J. L., AND DUBINSKY, J. M. Colocalization of excitatory and inhibitory neurotransmitter markers in striatal projection neurons in the rat. J. Comp. Neurol. 339: 328-340, 1994.
40. 1-Adrenergic receptor-mediated excitation from the locus coeruleus of the sacral parasympathetic preganglionic neuron. Life Sci. 47: 789-797, 1990.
41. YOSHIYAMA, M., ROPPOLO, J. R., AND DE GROAT, W. C. Alteration by urethane of glutamatergic control of micturition. Eur. J. Pharmacol. 264: 417-425, 1994.
42. ZUCKER, R. S. Short term synaptic plasticity. Annu. Rev. Neurosci. 12: 13-31, 1989.