Transforming activity of the E6 gene of HPV-11gt in NIH 3T3 and REF 52 cells: Correlation with the level of E6 transcription

Virology

Volumn 220, Issue 1, 1996, Pages 1-9

  Trujillo, Jorge M ^a   Mounts, Phoebe ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MOLECULAR HYBRIDIZATION; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; VIRUS CELL TRANSFORMATION; WART VIRUS;

ANIMALIA; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPES;

EID: 0029982579     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0279     Document Type: Article

References (49)

1. Barbosa, M. S., Vass, W. C., Lowy, D. R., and Schiller, J. T. (1991). In vitro biological activities of E6 and E7 genes vary among human papillomaviruses of different oncogenic potential. J. Virol. 65, 292-298.
2. Berg, J. M. (1986). Potential metal-binding domains in nucleic acid binding proteins. Science 242, 485-487.
3. Byrne, J. C., Tsao, M. S., Fraser, R. S., and Howley, P. M. (1987). Human papillomavirus-11 DNA in a patient with chronic tracheobronchial papillomatosis and metastatic squamous cell carcinoma of the lung. N. Engl. J. Med. 317, 873-878.
4. Chen, J. J., Reid, C. E., Band, V., and Androphy, E. J. (1995). Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein. Science 269, 529-531.
5. Chen, S.-L., and Mounts, P. (1990). Transforming activity of E5a protein of human papillomavirus type 6 in NIH 3T3 and C127 cells. J. Virol. 64, 3226-3243.
6. Crook, T., Tidy, J. A., and Vousden, K. H. (1991). Degradation of p53 can be targeted by HPV-E6 sequences distinct from those required for p53 binding and trans-activation. Cell 67, 547-556.
7. Dartmann, K., Schwartz, E., Gissmann, L., and Zur Hausen, H. (1986). The nucleotide sequence and genome organization of human papillomavirus type 11. Virology 151, 124-130.
8. Desaintes, C., Hallez, S., Alphen, P. V., and Burny, A. (1992). Transcriptional activation by several heterologous promoters by the E6 protein of human papillomavirus type 16. J. Virol. 66, 325-333.
9. de Villiers, E. M. (1989). Heterogeneity of the human papillomavirus group. J. Virol. 63, 4898-4903.
10. Doebritz, M. V. K., Rittmuller, C., Aengeneyndt, F., Jansen-Durr, P., and Spitkovsky, D. (1994). Reversible repression of papillomavirus oncogene expression in cervical carcinoma cells: Consequences for the phenotype and E6-p53 and E7-pRB interactions. J. Virol. 68, 2811-2822.
11. Farthing, A. J., and Vousden, K. H. (1994). Functions of human papillomavirus E6 and E7 oncoproteins. Trends Microbiol. 2, 170-174.
12. Gage, J. R., Meyers, C., and Wettstein, F. O. (1990). The E7 proteins of the nononcogenic human papillomavirus type 6b (HPV-6b) and of the oncogenic HPV-16 differ in retinoblastoma protein binding and other properties. J. Virol. 64, 724-730.
13. Giri, I., and Danos, O. (1986). Papillomavirus genomes: From sequence data to biological properties. Trends Genet. September, 227-242.
14. Gissmann, L. (1992). Papillomaviruses and human oncogenesis. Curr. Opinion Genet. Dev. 2, 97-102.
15. Gissmann, L., Wolnik, L., Ikenberg, H., Koldovsky, U., Schnürch, H. G., and zur Hausen, H. (1983). Human papillomaviruses types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers. Proc. Natl. Acad. Sci. USA 80, 560-563.
16. Gissmann, L., Diehl, V., Schultz-Coulon, H. J., and zur Hausen, H. (1982). Molecular cloning and characterization of human papillomavirus DNA derived from a laryngeal papilloma. J. Virol. 44, 393-400.
17. Grossman, S. R., and Laimins, L. A. (1989). E6 protein of human papillomavirus type 18 binds zinc. Oncogene 4, 1089-1093.
18. Halbert, C. L., Demers, G. W., and Galloway, D. A. (1992). The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells. J. Virol. 66, 2225-2234.
19. Halbert, C. L., Demers, G. W., and Galloway, D. (1991). The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells. J. Virol. 65, 473-478.
20. Hiraiwa, A., Kiyono, T., Segawa, K., Utsumi, K. R., Ohashi, M., and Ishibashi, M. (1993). Comparative study on E6 and E7 genes of some cutaneous and genital papillomaviruses of human origin for their ability to transform 3Y1 cells. Virology 192, 102-111.
21. Huibregtse, J. M., Scheffner, M., and Howley, P. (1991). A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J. 10(13), 4129-4135.
22. Iwasaka, T., Yokoyama, M., Hayashi, Y., and Sugimori, H. (1993). Human papillomavirus 16 and 18 DNA can solely induce oncogenic transformation of mammalian cells in primary culture. Acta Obstet. Gynecol. Scand. 72, 81-86.
23. Kiyono, T., Hiraiwa, A., and Ishibashi, M. (1992). Differences in transforming activity and coded amino acid sequence among E6 genes of several papillomaviruses associated with epidermodysplasia verruciformis. Virology 186, 628-639.
24. Kulski, J. K., Demeter, T., Mutavdzic, S., Sterrett, G. F., Mitchell, K. M., and Pixley, E. C. (1990). Survey of histologic specimens of human cervical cancer for human papillomavirus types 6/11/16/18 by filter in situ hybridization. Am. J. Clin. Pathol. 94, 566-570.
25. Lancaster, W., and Jensen, A. (1978). A natural history of human papillomavirus infection of the anogenital tract. Cancer Metastasis Rev. 6, 653-664.
26. Logan, J., Nicholas, J. C., Topp, W. C., Girard, M., Shenk, T., and Levine, A. J. (1981). Transformation by adenovirus early region 2A temperature-sensitive mutants and their revertants. Virology 115, 419-422.
27. McGlennen, R. C., Ghai, J., Ostrow, R. S., LaBresh, K., Schneider, J. F., and Faras, A. J. (1992). Cellular transformation by a unique isolate of human papillomavirus type 11. Cancer Res. 52, 5872-5878.
28. Metcalfe, L., Chen, S.-L., and Mounts, P. (1989). Structural analysis of human papillomavirus type 6c isolates from condyloma acuminatum and juvenile-onset and adult-onset laryngeal papillomata. Virus Genes 3(1), 11-27.
29. Mounts, P., Shah, K. V., and Kashima, H. (1982). Viral etiology of juvenile-and adult-onset squamous papilloma of the larynx. Proc. Natl. Acad. Sci. USA 79, 5425-5429.
30. Mounts, P., and Kelly, T. J. (1984). Rearrangements of host and viral DNA in mouse cells transformed by simian virus 40. J. Mol. Biol. 177, 431-460.
31. Peden, K. W. C., Charles, C., Sanders, L., and Tennekoon, G. (1989). Isolation of rat schwann cell lines: use of SV40 T Ag gene regulated by synthetic metallothionein promoters. Exp. Cell. Res. 185, 60-72.
32. Sanger, F., and Coulson, A. R. (1975). A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. J. Mol. Biol. 94, 441-448.
33. Scheffner, M., Werness, B. A., Huibregste, J. M., Levine, A. J., and Howley, P. M. (1990). The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes degradation of p53. Cell 63, 1129-1136.
34. Schiffman, M. H., Bauer, H. M., Hoover, R. N., Glass, A. G., Cadell, D. M., Rush, B. B., Scott, D. R., Sherman, M. E., Kurman, R. J., Wacholder, S., Stanton, C. K., and Manos, M. M. (1993). Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J. Natl. Cancer Inst. 85, 958-964.
35. Schmitt, A., Harry, J. B., Rapp, B., Wettstein, F. O., and Iftner, T. (1994). Comparison of the properties of the E6 and E7 genes of low-and high-risk cutaneous papillomavirus reveals strongly transforming and high Rb-binding activity for the E7 protein of the low-risk human papillomavirus type 1. J. Virol. 68, 7051-7059.
36. Schwarz, E., Durst, M., Demankowski, C., Lattermann, O., Zech, R., Wolfsperger, E., Duhai, S., and Zur Hausen, H. (1983). DNA sequence and genome organization of human papillomavirus type 6b. EMBO J. 2, 2441-2448.
37. Sedman, S. A., Barbosa, M. S., Vass, W. C., Hubert, N. L., Haas, J. A., Lowy, D. R., and Schiller, J. T. (1991). The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture. J. Virol. 65, 4860-4866.
38. Sedman, S. A., Hubbert, N. L., Vass, W. C., Lowy, D. R., and Schiller, J. T. (1992). Mutant p53 can substitute for human papillomavirus type 16 E6 in immortalization of human keratinocytes but does not have E6-associated trans-activation or transforming activity. J. Virol. 66, 4201-4208.
39. Shah, K. V., and Howley, P. M. (1990). Papillomaviruses. In "Virology" (B. N. Fields and D. M. Knipe, Eds.), pp. 1651-1676. Raven Press, New York.
40. Sort, S. (1990). "Statistics for Health Professionals," Saunders, Philadelphia.
41. Storey, A., Pim, D., Murray, A., Osborn, K., Banks, L., and Crawford, L. (1988). Comparison of the in vitro transforming activities of human papillomavirus types. EMBO J. 7, 1815-1820.
42. Storey, A., Osborn, K., and Crawford, L. (1990). Co-transformation by human papillomavirus types 6 and 11. J. Gen. Virol. 71, 165-171.
43. Storey, A., and Banks, L. (1993). Human papillomavirus type 16 E6 cooperates with EJ-ras to immortalize primary mouse cells. Oncogens 8, 919-924.
44. Sutton, G. P., Stehman, F. B., Ehrlich, C. E., and Roman, A. (1987). Human papillomavirus deoxyribonucleic acid in lesions of the female genital tract: Evidence for type 6/11 in squamous carcinoma of the vulva. Obstet. Gynecol. 70, 564-568.
45. Ward, P., and Mounts, P. (1988). Transcriptional activity of human papillomavirus type 6 in respiratory tract papillomata. J. Gen. Virol. 19, 1671-1682.
46. Werness, B. A., Levine, A. J., and Howley, P. M. (1990). Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 248, 76-79.
47. Wu, T.-C., and Mounts, P. (1989). Sensitive detection of nucleic acids and protein of human papillomavirus type 6 in respiratory and genital tract papillomata. J. Virol. Methods 25(1), 31-47.
48. Wu, T.-C., Trujillo, J. M., Kashima, H. K., and Mounts, P. (1993). Association of human papillomavirus with nasal neoplasia. Lancet 341, 522-524.
49. zur Hausen, H. (1987). Papillomaviruses in human cancer. Cancer 59, 1692-1696.