Kar4p, a karyogamy-specific component of the yeast pheromone response pathway

Molecular and Cellular Biology

Volumn 16, Issue 8, 1996, Pages 3990-4002

  Kurihara, Laurie Jo ^a   Stewart, Bruce G ^a   Gammie, Alison E ^a   Rose, Mark D ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PHEROMONE;

ARTICLE; CELL FUSION; CELL NUCLEUS; DIPLOIDY; FUNGUS MUTANT; GENE EXPRESSION; GENE INDUCTION; HAPLOIDY; MEIOSIS; MICROTUBULE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; YEAST;

EID: 0029982404     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.8.3990     Document Type: Article

References (49)

1. Berlin, V., C. A. Styles, and G. R. Fink. 1990. BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin. J. Cell Biol. 111:2573-2586.
2. Burns, N., B. Grimwade, P. B. Ross-Macdonald, E.-Y. Choi, K. Finberg, G. S. Roeder, and M. Snyder. 1994. Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae. Genes Dev. 8:1087-1105.
3. Defoor, E., R. Debrabandere, B. Keyers, M. Voet, and G. Volckaert. 1992. Nucleotide sequence of D10B, a BamHI fragment on the small-ring chromosome III of Saccharomyces cerevisiae. Yeast 8:681-687.
4. Dolan, J. W., and S. Fields. 1990. Overproduction of the yeast STE12 protein leads to constitutive transcriptional induction. Genes Dev. 4:492-502.
5. Dolan, J. W., C. Kirkman, and S. Fields. 1989. The yeast STE12 protein binds to the DNA sequence mediating pheromone induction. Proc. Natl. Acad. Sci. USA 86:5703-5707.
6. Endow, S. A., S. J. Kang, L. L. Satterwhite, M. D. Rose, V. P. Skeen, and E. D. Salmon. 1994. Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends. EMBO J. 13:2708-2713.
7. Errede, B., and G. Ammerer. 1989. STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes. Genes Dev. 3:1349-1361.
8. Gimeno, C. J., P. O. Ljungdahl, C. A. Styles, and G. R. Fink. 1992. Unipolar cell divisions in the yeast Saccharomyces cerevisiae lead to filamentous growth: regulation by starvation and ras. Cell 68:1077-1090.
9. Guarente, L., and M. Ptashne. 1981. Fusion of Escherichia coli LacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 78:2199-2203.
10. Hagen, D. C., G. McCaffrey, and G. F. Sprague. 1991. Pheromone response elements are necessary and sufficient for basal and pheromone-induced transcription of the FUSI gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 11:2952-2961.
11. Hereford, L. M., and L. H. Hartwell. 1974. Sequential gene function in the initiation of Saccharomyces cerevisiae. DNA synthesis J. Mol. Biol. 84:445-461.
12. Hoffman, C. S., and F. Winston. 1987. A ten minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of E. coli. Gene 57:267-272.
13. Huffaker, T. C., J. H. Thomas, and D. Botstein. 1988. Diverse effects of β-tubulin mutations on microtubule formation and function. J. Cell Biol. 106:1997-2010.
14. Kassir, Y., and G. Simchen. 1991. Monitoring meiosis and sporulation in Saccharomyces cerevisiae. Methods Enzymol. 194:94-109.
15. Koch, C., and K. Nasmyth. 1994. Cell cycle regulated transcription in yeast. Curr. Opin. Cell Biol. 6:451-459.
16. Kronstad, J. W., J. A. Holly, and V. L. MacKay. 1987. A yeast operator site overlaps an upstream activation site. Cell 50:369-377.
17. Kurihara, L. J., C. T. Beh, M. Latterich, R. Schekman, and M. D. Rose. 1994. Nuclear congression and membrane fusion: two distinct events in the yeast karyogamy pathway. J. Cell Biol. 126:911-923.
18. Latterich, M., and R. Schekman. 1994. The karyogamy gene KAR2 and novel proteins are required for ER membrane fusion. Cell 78:87-98.
19. Liu, H., C. A. Styles, and G. R. Fink. 1993. Elements of the yeast pheromone response pathway required for filamentous growth of diploids. Science 262: 1741-1744.
20. McCaffrey, G., F. J. Clay, K. Kelsay, and G. F. Sprague, Jr. 1987. Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 7:2680-2690.
21. Meluh, P. B. 1992. KAR3, a kinesin-related gene required for nuclear fusion, mitosis and meiosis in Saccharomyces cerevisiae. Ph.D. thesis. Princeton University Department of Molecular Biology, Princeton, N.J.
22. Meluh, P. B., and M. D. Rose. 1990. KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell 60:1029-1041.
23. Middleton, K., and J. Carbon. 1994. KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding protein (CBF3) on an in vitro yeast kinetochore. Proc. Natl. Acad. Sci. USA 91:7212-7216.
24. Oehlen, L. J. W. M., and F. R. Cross. 1994. G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at Start in the yeast cell cycle. Genes Dev. 8:1058-1070.
25. Ohashi, A., J. Gibson, I. Gregor, and G. Schatz. 1982. Import of proteins into mitochondria. J. Biol. Chem. 257:13042-13047.
26. Oliver, S. G., et al. 1992. The complete DNA sequence of yeast chromosome III. Nature (London) 357:38-46.
27. Page, B. D., L. L. Satterwhite, M. D. Rose, and M. Snyder. 1994. Localization of the KAR3 kinesin heavy chain-like protein requires the CIK1 interacting protein. J. Cell Biol. 124:507-519.
28. Page, B. D., and M. Snyder. 1992. CIK1: a developmentally regulated spindle pole body-associated protein important for microtubule functions in Saccharomyces cerevisiae. Genes Dev. 6:1414-1429.
29. Riles, L., J. E. Dutchik, A. Baktha, B. K. McCauley, E. C. Thayer, M. P. Leckie, V. V. Braden, J. E. Depke, and M. V. Olson. 1993. Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs. Genetics 134:81-150.
30. Rose, M. D. 1991. Nuclear fusion in yeast. Annu. Rev. Microbiol. 45:539-567.
31. Rose, M. D., and G. R. Fink. 1987. KAR1, a gene required for function of both intranuclear and extranuclear microtubules in yeast. Cell 48:1047-1060.
32. Rose, M. D., P. Novick, J. H. Thomas, D. Botstein, and G. R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60:237-243.
33. Rose, M. D., F. Winston, and P. Hieter. 1990. Methods of yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
34. Rothstein, R. J. 1983. One-step gene disruption in yeast. Methods Enzymol. 101:202-211.
35. Satterwhite, L., and M. Rose. Unpublished data.
36. Saunders, W. S., and M. A. Hoyt. 1992. Kinesin-related proteins required for structural integrity of the mitotic spindle. Cell 70:451-458.
37. Scidmore, M. 1993. A genetic analysis of KAR2, the yeast homologue of mammalian BiP. Ph.D. thesis. Princeton University Department of Molecular Biology, Princeton, N.J.
38. Scidmore, M. A., H. H. Okamura, and M. D. Rose. 1993. Genetic interactions between KAR2 and SEC63, encoding eukaryotic homologues of DnaK and DnaJ in the endoplasmic reticulum. Mol. Biol. Cell 4:1145-1159.
39. Sengupta, P., and B. H. Cochran. 1990. The PRE and PQ box are functionally distinct yeast pheromone response elements. Mol. Cell. Biol. 10:6809-5812.
40. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:9-27.
41. Sprague, G. F., and J. Thorner. 1992. Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae, p. 657-744. In J. R. Broach, J. R. Pringle, and E. W. Jones (ed.), The molecular biology of the yeast Saccharomyces, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
42. Stewart, B., A. Gammie, and M. Rose. Unpublished data.
43. Trueheart, J., J. D. Boeke, and G. R. Fink. 1987. Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol. Cell. Biol. 7:2316-2328.
44. Vallen, E. A., M. A. Hiller, T. Y. Scherson, and M. D. Rose. 1992. Separate domains of KAR1 mediate distinct functions in mitosis and nuclear fusion. J. Cell Biol. 117:1277-1287.
45. Van Arsdell, S. W., G. L. Stetler, and J. Thorner. 1987. The yeast repeated element sigma contains a hormone-inducible promoter. Mol. Cell. Biol. 7:749-759.
46. Wilson, I. A., H. L. Niman, R. A. Houghten, A. R. Cherenson, M. L. Connolly, and R. A. Lerner. 1984. The structure of an antigenic determinant in a protein. Cell 37:767-778.
47. Yuan, Y. O., and S. Fields. 1991. Properties of the DNA-binding domain of the Saccharomyces cerevisiae Ste12 protein. Mol. Cell. Biol. 11:5910-5918.
48. Yuan, Y. O., I. L. Stroke, and S. Fields. 1993. Coupling of cell identity to signal response in yeast: interaction between the α1 and STE12 proteins. Genes Dev. 7:1584-1597.
49. Zanolari, B., and H. Riezman. 1991. Quantitation of α-factor internalization and response during the Saccharomyces cerevisiae cell cycle. Mol. Cell. Biol. 11:5251-5258.