Hemochromatosis: Diagnosis and management

American Family Physician

Volumn 53, Issue 8, 1996, Pages 2623-2628

  Little, David R ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFERIPRONE; DEFEROXAMINE; FERRITIN; TRANSFERRIN;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; DIABETES MELLITUS; DIAGNOSTIC APPROACH ROUTE; FERRITIN BLOOD LEVEL; HEMOCHROMATOSIS; HUMAN; LIVER BIOPSY; LIVER DYSFUNCTION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PHLEBOTOMY; TRANSFERRIN BLOOD LEVEL; TREATMENT PLANNING;

ADULT; DIAGNOSIS, DIFFERENTIAL; HEMOCHROMATOSIS; HUMANS; MALE; PROGNOSIS;

EID: 0029982397     PISSN: 0002838X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Tavill AS, Bacon BR. Hemochromatosis: iron metabolism and the iron overload syndromes. In: Zakim D, Boyer TD, eds. Hepatology: a textbook of liver disease. Philadelphia: Saunders, 1990:1273-94.
2. Niederau C, Fischer R, Sonnenberg A, Stremmel W, Trampisch HJ, Strohmeyer G. Survival and causes of death in cirrhotic and noncirrhotic patients with primary hemochromatosis. N Engl J Med 1985;313:1256-62.
3. Nichols GM, Bacon BR. Hereditary hemochromatosis: pathogenesis and clinical features of a common disease. Am J Gastroenterology 1989;84:851-62.
4. Adams PC, Gregor J. Hemochromatosis and yersiniosis. Can J Gastroenterol 1990;4:160-2.
5. Edwards CQ, Griffen LM, Goldgar D, Drummond C, Skolnick MH, Kushner JP. Prevalence of hemochromatosis among 11,065 presumably healthy blood donors. N Engl J Med 1988;318:1355-62.
6. Rouault TA. Hereditary hemochromatosis. JAMA 1993;269:3152-4.
7. Bassett ML, Halliday JW, Powell LW. HLA typing in idiopathic hemochromatosis: distinction between homozygotes and heterozygotes with biochemical expression. Hepatology 1981;1:120-6.
8. Olynyk JK, Bacon BR. Hereditary hemochromatosis. Detecting and correcting iron overload. Postgrad Med 1994;96(5):151-8,161,165.
9. Adams PC, Kertesz AE, Valberg LS. Clinical presentation of hemochromatosis: a changing scene. Am J Med 1991;90:445-9.
10. Edwards CQ, Cartwright GE, Skolnick MH, Amos DB. Homozygosity for hemochromatosis: clinical manifestations. Ann Intern Med 1980;93:519-25,
11. Bassett ML, Halliday JW, Powell LW. Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis. Hepatology 1986;6:24-9.
12. Di Bisceglie AM, Axiotis CA, Hoofnagle JH, Bacon BR. Measurements of iron status in patients with chronic hepatitis. Gastroenterology 1992;102:2108-13.
13. Gandon Y, Guyader D, Heautot JF, Reda MI, Yaouanq J, Buhe T, et al. Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging. Radiology 1994;193:533-8.
14. Cutler P. Deferoxamine therapy in high-ferritin diabetes. Diabetes 1989;38:1207-10.
15. Olivieri NF, Brittenham GM, Matsui D, Berkovitch M, Blendis LM, Cameron RG, et al. Iron-chelation therapy with oral deferiprone in patients with thalassemia major. N Engl J Med 1995;332:918-22.
16. Adams PC, Speechley M, Kertesz AE. Long-term survival analysis in hereditary hemochromatosis. Gastroenterology 1991;101:368-72.
17. Fargion S, Fracanzani AL, Piperno A, Braga M, D'Alba R, Ronchi G, et al. Prognostic factors for hepatocellular carcinoma in genetic hemochromatosis. Hepatology 1994;20:1426-31.
18. Balan V, Baldus W, Fairbanks V, Michels V, Burritt M, Klee G. Screening for hemochromatosis: a cost-effectiveness study based on 12,258 patients. Gastroenterology 1994;107:453-9.
19. Phatak PD, Guzman G, Woll JE, Robeson A, Phelps CE. Cost-effectiveness of screening for hereditary hemochromatosis. Arch Intern Med 1994;154:769-76.
20. Phelps G, Chapman I, Hall P, Braund W, Mackinnon M. Prevalence of genetic haemochromatosis among diabetic patients. Lancet 1989;2(8657): 233-4.