Tailoring echistatin to possess higher affinity for integrin αiibβ3

FEBS Letters

Volumn 387, Issue 1, 1996, Pages 11-15

  Yamada, Takao ^a   Kidera, Akinori ^a  

^a BIOMOL ENG RESEARCH INSTITUTE   (Japan)

Author keywords

Arg Gly Asp; Conformational constraint; Echistatin; Integrin IIb 3; Monte Carlo simulation; Type II turn

Indexed keywords

DISINTEGRIN; ECHISTATIN; FIBRINOGEN; FIBRINOGEN RECEPTOR;

ARTICLE; BINDING AFFINITY; COMPUTER SIMULATION; HUMAN; MASS SPECTROMETRY; MUTANT; PEPTIDE MAPPING; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMINO ACID SEQUENCE; DISULFIDES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; OLIGOPEPTIDES; PEPTIDES; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0029982188     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00409-7     Document Type: Article

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