The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-β, and embryonic mouse lung development in vivo

Pediatric Research

Volumn 39, Issue 5, 1996, Pages 749-759

  Jaskoll, Tina ^a   Choy, Henry A ^a   Melnick, Michael ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN; MESSENGER RNA; MONOCLONAL ANTIBODY; SURFACTANT ASSOCIATED PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; TRIAMCINOLONE HEXACETONIDE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA BINDING; EMBRYO; EMBRYO DEVELOPMENT; FETUS LUNG MATURATION; GENE EXPRESSION; LUNG DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0029981943     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199605000-00002     Document Type: Article

References (94)

1. Ballard PL 1989 Hormonal regulation of pulmonary surfactant. Endocr Rev 10:165-181
2. Kresch MJ, Gross I 1987 The biochemistry of fetal lung development. Clin Perinatol 14:481-507
3. Weaver TE, Whitsett JA 1991 Function and regulation of pulmonary surfactant-associated proteins. Biochem J 273:249-264
4. Danielpour D, Kim KY, Winokur TS, Sporn MB 1991 Differential regulation of the expression of transforming growth factor-β1 and 2 by retinoic acid, epidermal growth factor, and dexamethasone in NRK-49F and A549 cells. J Cell Physiol 148:235-244
5. Oberg KC, Carpenter G 1989 Dexamethasone acts as a negative regulator of epidermal growth factor receptor synthesis in fetal rat lung cells. Mol Endocrinol 3:915-922
6. Oberg KC, Carpenter G 1991 Dexamethasone and retinoic acid regulate the expression of epidermal growth factor receptor mRNA by distinct mechanisms. J Cell Physiol 149:244-251
7. Phelps DS, Church S, Kourembanas S, Taeusch HW, Floros J 1987 Increases in the 35 kDa surfactant-associated protein and its mRNA following in vivo dexamethasone treatment of fetal and neonatal rats. Electrophoresis 8:235-238
8. Guettari N, Marin L, Bourbon J, Dufour ME, Rietort M, Tordet C 1989 Effects of the antiglucocorticoid RU486 on the maturation of fetal rat lung surfactant. Exp Lung Res 15:151-166
9. Jaskoll TF, Don-Wheeler G, Johnson R, Slavkin HC 1988 Embryonic mouse lung morphogenesis and type II cytodifferentiation in serumless, chemically defined medium using prolonged in vitro culture. Cell Differ 24:105-118
10. Hu CC, Jaskoll T, Minkin C, Melnick M 1990 The mouse major histocompatibility complex (H-2) and fetal lung development: implications for human pulmonary maturation. Am J Med Genet 35:126-131
11. Kauffman SL 1977 Acceleration of canalicular development in lungs of fetal mice exposed transplacentally to dexamethasone. Lab Invest 36:395-401
12. Schellhase DE, Shannon JM 1991 Effects of maternal dexamethasone on expression of SP-A, SP-B, SP-C in the fetal rat lung. Am J Res Cell Mol Biol 4:304-312
13. Wilson GN 1993 Relevance of the genetics of embryonic development. Growth Gen Horm 9:1-5
14. Winter RM 1993 The importance and methods of using animal models to study human disease. Growth Gen Horm 9:6-8
15. Jaskoll T, Hu CC, Melnick M 1991 Mouse major histocompatibility complex and lung development: haplotype variation, H-2 immunolocalization and progressive maturation. Am J Med Genet 36:422-436
16. Boyer P, Rich KA, Jaskoll T, Melnick M 1994 IGF-II receptors and heterochronic embryonic lung development. Endocrinology 134:547A
17. Becker B, Shin DH, Palmberg PF, Waltman SR 1976 HLA antigens and corticosteroid response. Science 194:1427-1428
18. Hafez M, El-Sallab SH, Khashaba M, Risk MS, El-Morsy Z, Bassiony MR, Elkenawy F, Zaghloul W 1989 Evidence of HLA-linked susceptibility gene(s) in respiratory distress syndrome. Dis Markers 7:201-208
19. Beato M 1989 Gene regulation by steroid hormones. Cell 56:335-344
20. Meisfeld R 1989 The structure and function of steroid receptor proteins. Crit Rev Biochem Mol Biol 24:101-117
21. Yamamoto KR 1985 Steroid regulated transcription of specific genes and gene networks. Annu Rev Genet 19:209-252
22. Giguere V, Evans RM 1990 Identification of receptors for retinoids as members of the steroid and thyroid hormone receptor family. Methods Enzymol 189:223-232
23. Gross I, Ballard PL, Ballard RA 1983 Corticosteroid stimulation of phospatidylcholine synthesis in cultured fetal rabbit lung. Evidence for de novo protein synthesis mediated by glucocorticoid receptors. Endocrinology 112:829-837
24. Ballard PL, Gonzales LK 1984 Mechanism of glucocorticoid and thyroid hormone action in fetal lung. In: Raivio KO, Hallman N, Kouvalainen, Valimaki I (eds) Respiratory Distress Syndrome. Academic Press, New York, pp 67-86
25. Jaskoll T, Boyer PD, Melnick M 1994 TNF-α and embryonic mouse lung morphogenesis. Dev Dyn 201:137-150
26. Pratt, WB 1993 The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor. J Biol Chem 268:21455-21458
27. Melnick M, Jaskoll T, Slavkin HC 1981 The association of H-2 haplotype with implantation, survival, and growth of murine embryos. Immunogenetics 13:303-308
28. Theiler K 1972 The House Mouse. Springer-Verlag, Berlin
29. Jaskoll T, Choy HA, Cheri H, Melnick M 1995 The CORT-GR signal transduction pathway and CORT-induced cleft palate in H-2 congenic mice. J Craniofac Genet Dev Biol 15:57-65
30. Bradford M 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
31. Jaskoll T, Luttge WG, Sakai DD, Nichols NR, Melnick M 1993 H-2 gene complex and corticosteroid responsiveness: evidence that the corticosteroid hormone signal transduction pathway in the adult mouse lung is not associated with haplotype-specific responses to corticosteroids. Steroids 58:400-406
32. Eisen LP, Reichman ME, Thompson EB, Gametchu B, Harrison RW. Eisen HJ 1985 Monoclonal antibody to the rat glucocorticoid receptor. Relationship between the immunoreactive and DNA-binding domain. J Biol Chem 260:11805-11810
33. Gametchu B, Harrison RW 1984 Characterization of a monoclonal antibody to the rat liver glucocorticoid receptor. Endocrinology 114:274-279
34. Northrop JP, Gametchu B, Harrison RW, Ringold GM 1985 Characterization of wild type and mutant glucocorticoid receptors from rat hepatoma and mouse lymphoma cells. J Biol Chem 260:6398-6403
35. Whitsett JA, Weaver TE, Hull H, Ross G, Dion C 1985 Synthesis of surfactant-associated glycoprotein A by rat type II epithelial cells. Primary translation products and post-translational modification. Biochim Biophys Acta 828:162-171
36. Weaver TE, Hull WM, Ross GR, Whitsett JA 1985 Intracellular and oligomeric forms of surfactant-associated apolipoprotein(s) in the rat. Biochim Biophys Acta 827:260-267
37. Slavkin HC, Johnson R, Oliver P, Bringas P, Don-Wheeler G, Mayo M, Whitsett JA 1989 Lamellar body formation precedes surfactant apoprotein expression during embryonic mouse lung development in vivo and in vitro. Differentiation 41:223-236
38. Garner M, Revzin A 1981 A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: applications to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res 9:3047-3060
39. Fried M, Crothers DM 1981 Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res 9:6505-6525
40. Strahle U, Kloch G, Schutz G 1987 A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression. Proc Natl Acad Sci USA 84:7871-7875
41. Sokal RR, Rohlf FF 1981 Biometry. W. H. Freeman Co., San Francisco
42. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
43. Derynck R, Jarrett JA, Chen EY, Goeddel DV 1986 The murine transforming growth factor precursor. J Biol Chem 261:4377-4379
44. Miller DA, Lee A, Pelton RW, Chen EY, Moses HL, Derynck R 1989 Murine transforming growth factor-β2 cDNA sequences and expression in adult tissues and embryos. Mol Endocrinol 3:1108-1114
45. Denhez F, Layyatis R, Kondiah P, Roberts A, Sporn M 1990 Cloning by polymerase chain reaction a new mouse TGF-β, mTGFβ3. Growth Factors 3:139-146
46. Fisher JH, Emrie PA, Shannon J, Sano K, Hattler B, Mason RJ 1988 Rat pulmonary surfactant protein A is expressed as two differently sized mRNA species which arise from differential polyadenylation of one transcript. Biochim Biophys Acta 950:338-345
47. Jaskoll TF, Slavkin HC 1984 Ullrastructural and immunofluorescence studies of basal-lamina alterations during mouse-lung morphogenesis. Differentiation 28:36-48
48. Kalinyak JE, Griffin CA, Hamilton RW, Bradshw JG, Perlman AJ, Hoffman AR 1989 Developmental and hormonal regulation of glucocorticoid receptor messenger RNA in the rat. J Clin Invest 84:1843-1848
49. Kalimi M, Hubbard J, Gupta S 1988 Modulation of glucocorticoid receptor from development to aging. Ann NY Acad Sci 521:149-154
50. Bronnegard M, Okret S 1988 Characterization of the glucocorticoid receptor in fetal lung during development: influence of proteolytic activity. J Steroid Biochem 31:809-817
51. Cadepond F, Schweizer-Groyer G, Segard-Maurel I, Jibard N, Hollenberg SM, Giguere V, Evans RM, Baulieu E-E 1991 Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a functional state. J Biol Chem 266:5834-5841
52. Pratt WB, Scherrer LC, Hutchinson KA, Dalman FC 1992 A model of glucocorticoid receptor unfolding and stabilization by a heat shock protein complex. J Steroid Biochem Mol Biol 41:223-229
53. Sanchez, ER, Hirst M, Scherrer LC, Tang H-Y, Welsch MJ, Harmon JM, Simmons SS, Ringold GM, Pratt WB 1990 Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90. J Biol Chem 265:20123-20130
54. Odom MJ, Snyder JM, Boggaram V, Mendelson CR 1988 Glucocorticoid regulation of the major surfactant associated protein (SP-A) and its messenger ribonucleic acid and of morphological development of human fetal lung in vitro. Endocrinology 123:1712-1720
55. Iannuzzi DM, Ertsey R, Ballard PL 1993 Biphasic glucocorticoid regulation of pulmonary SP-A: characterization of inhibitory process. Am J Physiol 264:L236-L244
56. Deterding RR, Shimizu H, Fisher JH, Shannon JM 1994 Regulation of surfactant protein D expression by glucocorticoids in vitro and in vivo. Am J Res Cell Mol Biol 10:30-37
57. Lacaze-Masmonteil T, Fraslon C, Bourbon J, Raymondjean M, Kahn A 1992 Characterization of the rat pulmonary surfactant protein A promoter. Eur J Biochem 206:613-623
58. Jaskoll TF, Phelps D, Taeusch HW, Smith BT, Slavkin HC 1984 Localization of pulmonary surfactant protein during mouse lung development. Dev Biol 106:256-261
59. Heine UI, Munoz E, Flanders KC, Roberts AB, Sporn MB 1990 Colocalization of TGF-β 1 and collagen I and III, fibronectin and glycosaminoglycans during lung branching morphogenesis. Development 109:29-36
60. Pelton RW, Dickinson ME, Moses HL, Hogan BL 1990 In situ hybridization analysis of TGF-β3 RNA expression during mouse development: comparative studies with TGFβ1 and TGF-β2. Development 110:609-620
61. Pelton RW, Moses HL 1990 The Beta-type transforming growth factor: mediators of cell regulation in the lung. Am Rev Respir Dis 142:S31-S35
62. Pelton RW, Saxena B, Jones M, Moses HL, Gold LI 1991 Immunohistochemical localization of TGFβ1, TGFβ2, and TGFβ3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol 115:1091-1105
63. Millan FA, Denhez F, Kondaiah P, Akhurst RJ 1991 Embryonic gene expression patterns of TGF β1, β2 and β3 suggest different developmental functions in vivo. Development 111:131-144
64. Nichols NR, Finch CE 1991 Transforming growth factor-β1 mRNA decreased in brain in response to glucocorticoid treatment of adrenalectomized rats. Mol Cell Neurosci 2:221-227
65. Jaskoll T, Choy HA, Melnick M 1994 Glucocorticoids, TGF-β, and embryonic mouse salivary gland morphogenesis. J Craniofac Genet Dev Biol 14:217-230
66. Warburton D, Bu DS, Lee MK, Wuendschell CM, Hall FL, Slavkin HC 1994 Role of transforming growth factor (TGF) β signalling in early mouse embryo lung branching morphogenesis: crosstalk with EGF signalling pathways. Am J Respir Crit Care Med 149:A255
67. r = 35,000 surfactant-associated protein in fetal lung. J Biol Chem 262:7908-7913
68. Torday JS, Kourembanas S 1990 Fetal rat lung fibroblasts produce a TGFβ homolog that blocks alveolar type II cell maturation. Dev Biol 139:35-41
69. Caniggia I, Tseu I, Han RN, Smith BT, Tanswell K, Post M 1991 Spatial and temporal differences in fibroblast behavior in fetal rat lung. Am J Physiol 261:L424-L433
70. Ten Have-Opbroek AAW 1981 The development of the lung in mammals: An analysis of concepts and findings. Am J Anat 162:201-219
71. Farrell PM 1982 Morphologic aspects of lung maturation. In Farrell PM (ed) Lung Development: Biologic and Clinical perspectives. Academic Press, New York, pp 13-27
72. Snyder JM, Mendelson CR, Johnston JM 1985 The morphology of human fetal lung development. Lung Biol Health Dis 27:19-46
73. 3H]dexamethasone binding in fetal lung. Dev Biol 105:351-364
74. Morrison NA, Qi JC, Tokita A, Kelly PA, Crofts L, Nguyen TV, Sambrook PN, Eisman JA 1994 Prediction of bone density from vitamin D receptor alleles. Nature 367:284-287
75. Cole TJ, Blendy JA, Schmid W, Strahle U, Shutz G 1993 Expression of the mouse glucocorticoid receptor and its role during development. J Steroid Biochem Mol Biol 47:49-53
76. Murphy BEPJ 1979 Cortisol and cortisone in human fetal development. J Steroid Biochem 11:509-513
77. Wessells NK 1977 Tissue Interactions and Development. Benjamin Cummins, Menlo Park, CA
78. Grant MM, Cutts NR, Brody JS 1983 Alterations in lung basement membrane during fetal growth and type-2 cell development. Dev Biol 97:173-183
79. Adamson IYR, King GM 1986 Epithelial-interstitial cell interactions in fetal rat lung development accelerated by steroids. Lab Invest 50:456-460
80. Snyder JM, Rodgers H, O'Brien J, Mahli N, Magliato S, Durham P 1992 The effects of glucocorticoids on rabbit fetal lung maturation in vivo: an ultrastructural morphometric study. Anat Rec 232:133-140
81. Reisfeld S, Vardimon L 1994 Cell to cell contacts control the transcription activity of the glucocorticoid receptor. Mol Endocrinol 94:1224-1233
82. Doyle D, Smith R, Krozowski ZS, Funder JW 1989 Mineralocorticoid specificity of renal type I receptors: binding and metabolism of corticosterone. J Steroid Biochem 33:165-170
83. Godowski PJ, Picard D 1989 How to be both a receptor and transcription factor. Biochem Pharmacol 38:3135-3143
84. Schule R, Rangarajan P, Kliewer S, Ransone LJ, Bolado J, Yang N, Verms IM, Evans RM 1990 Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 62:1217-1226
85. Sanchez ER, Toft DO, Schlesinger MJ, Pratt WB 1985 The 90 kD non-steroid-binding phosphoprotein that binds to the untransformed glucocorticoid receptor in molybdate stabilized L-cell cytosol is the murine 90 kD heat shock protein. J Biol Chem 260:12398-12401
86. Torday JS 1989 Transforming growth factor-β (TGFβ) blocks human fetal lung maturation while stimulating growth in expiant culture. Pediatr Res 25:62A
87. Torday JS 1992 Cellular timing of fetal lung development. Semin Perinatol 16:130-139
88. Whitsett JA, Budden A, Hull WM, Clark JC, O'Reilly 1992 Transforming growth factor-β inhibits surfactant protein A expression in vitro. Biochim Biophys Acta 1123:257-262
89. Wang J, Kuliszewski, Yee W, Sedlackova L, Xu J, Tseu I, Post M 1995 Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. J Biol Chem 270:2722-2728
90. Serra R, Pelton RW, Moses HL 1994 TGFβ1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. Development 120:2153-2161
91. Charron J, Malynn BA, Fisher P, Stewart V, Jeannotte L, Goff SP, Robertson EJ, Alt FW 1992 Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. Genes Dev 6:2248-2257
92. Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada L 1992 Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes Dev 6:2235-2247
93. Moens CB, Stanton BR, Parada LF, Rossant J 1993 Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus. Development 119:485-499
94. Cheifetz S, Hernandez H, Laiho M, ten Dijke P, Iwata KK, Massagues J 1990 Distinct transforming growth factor-β (TGFβ) receptor subsets as determinants of cellular responsiveness to three TGF-β isoforms. J Biol Chem 265:20533-20538