Cytokine patterns and viral load in lymph nodes during the early stages of SIV infection

Research in Virology

Volumn 147, Issue 2-3, 1996, Pages 181-189

  Khatissian, E ^a   Chakrabarti, L ^a   Hurtrel, B ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

AIDS; Cytokine; Early infection stages; Lymph node; SIV

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION; IMMUNE RESPONSE; IN SITU HYBRIDIZATION; LYMPH NODE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION; VIRUS REPLICATION;

ANIMALIA; MACACA MULATTA; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0029981692     PISSN: 09232516     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-2516(96)80233-0     Document Type: Conference Paper

References (14)

1. Biberfeld, P., Chayt, K.J., Marselle, L.M., Biberfeld, G., Gallo, R.C. & Harper, M.E. (1986), HTLV-III expression in infected lymph nodes and relevance to pathogenesis of lymphadenopathy. Am. J. Pathol., 125, 436-442.
2. Chalifoux, L.V., Ringler, D.J., King, N.W., Sehgal, P.K., Desrosiers, R.C., Daniel, M.D. & Letvin, N.L. (1987), Lymphadenopathy in macaques experimentally infected with the simian immunodeficiency virus. Am. J. Pathol., 128, 104-110.
3. Chakrabarti, L., Guyader, M., Alizon, M., Daniel, M.D., Desrosiers, R.C., Tiollais, P. & Sonigo, P. (1987), Sequence from simian immunodeficiency virus from macaques and its relationship to other human and simian retroviruses. Nature (Lond.), 328, 543-547.
4. Chakrabarti, L., Isola, P., Cumont, M.C., Claessens-Maire, M.A., Hurtrel, M., Montagnier, L. & Hurtrel, B. (1994a), Early stages of SIV infection in lymph nodes. Evidence for high virus load and successive populations of target cells. Am. J. Pathol., 144, 1226-1237.
5. Chakrabarti, L., Cumont, M.C., Montagnier, L. & Hurtrel, B. (1994b), Variable course of primary simian immunodeficiency virus infection in lymph nodes: relation to disease progression. J. Virol., 68, 6634-6643.
6. Clerici, M. & Shearer, M. (1993), A TH1/TH2 switch is a critical step in the etiology of HTV infection. Immunol. Today, 14, 107-111.
7. Emilie, D., Peuchmaur, M., Maillot, M.C., Crevon, M.C., Brousse, N., Delfraissy, J.F., Dormont, J. & Galanaud, P. (1990), Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes. J. Clin. Invest., 86, 148-159.
8. Gaines, H., Von Sydow, M.A.E., Von Stedingk, L.V., Biberfield, G., Böttiger, B., Hansson, L.O., Lundbergy, P., Sönnerborg, A.B., Wasserman, J. & Strannergard, O.O. (1990), Immunological changes in primary HIV-1 infection. AIDS, 4, 995-999.
9. Kaaya, E., Li, S.L., Feichtinger, H., Stahmer, I., Putkonen, P., Mandache, E., Mgaya, E., Biberfeld, G. & Biberfeld, P. (1993), Accessory cells and macrophages in the histopathology of SIVsm-infected cynomolgus monkeys. Res. Virol., 144, 81-92.
10. Li, S.L., Kaaya, E.E., Feichtinger, H., Putkonen, P., Parravicini, C., Bottiger, D., Biberfeld, G. & Biberfeld, P. (1991), Monocyte/macrophage giant cell disease in SIV-infected cynomolgus monkeys. Res. Virol., 142, 173-182.
11. Pantaleo, G., Graziosi, C., Demarest, J.F., Butini, L., Montroni, M., Fox, C.H., Orenstein, J.M., Kotler, D.P. & Fauci, A.S. (1993), HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature (Lond.), 362, 355-358.
12. Sheppard, H.W., Ascher, M.S., McRae, B., Anderson, R.E., Lang, W. & Allain, J.P. (1991), The initial immune response to HIV and immune system activation determine the outcome of HIV disease. J. Acquired Immune Defic. Syndr., 4, 704-712.
13. Stahmer, I., Zimmer, J.P., Ernst, M., Fenner, T., Finnern, R., Schmitz, H., Flad, H.D. & Gerdes, J. (1991), Isolation of normal human follicular dendritic cells and CD4-independent in vitro infection by human immunodeficiency virus (HIV-1). Eur. J. Immunol., 21, 1873-1878.
14. Tindall, B. & Cooper, D.A. (1990), Primary HIV infection: host responses and intervention strategies. AIDS, 5, 1-14.