Roles of active site residues and the NH2-terminal domain in the catalysis and substrate binding of human Cdc25

Journal of Biological Chemistry

Volumn 271, Issue 9, 1996, Pages 5118-5124

  Xu, Xu ^a   Burke, Shannon Plisinski ^a  

^a GPC Biotech Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOPROTEIN PHOSPHATASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL CYCLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; GROWTH REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CATALYSIS; CATTLE; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CLONING, MOLECULAR; DNA PRIMERS; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; PHOSPHOPROTEIN PHOSPHATASE; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; SUBSTRATE SPECIFICITY; THROMBIN;

EID: 0029981395     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.9.5118     Document Type: Article

References (56)

1. Draetta, G , Piwnica-Worms, H., Morrison, D., Druker, B , Roberts, T., and Beach, D. (1988) Nature 326, 738-744
2. Gould, K., and Nurse, P, (1989) Nature 342, 39-45
3. Krek, W., and Nigg, E (1991) EMBO J 10, 305-316
4. Norbury, C., Blow, J., and Nurse, P, (1991) EMBO J. 10, 3321-3329
5. Russell, P., and Nurse, P. (1987) Cell 49, 559-567
6. Parker, L., Atheron-Fessler, S., and Piwruca-Worms, H. (1992) Proc. Natl. Acad. Sci U. S. A. 89, 2917-2921
7. Poon, R Y. C., Yamashita, K., Adamczewski, J. P . Hunt, T , and Shuttleworth, J. (1993) EMBO. J. 12, 3123-3132
8. Solomon, M. J., Harper, J W., and Shuttleworth, J. (1993) EMBO J. 12, 3133-3142
9. Dunphy, W. G., and Kumagai, A (1991) Cell 67, 189-196
10. Gautier, J , Solomon, M. J., Booher, R. N., Bazan, J. F , and Kirschner, M W. (1991) Cell 67, 197-211
11. Millar, J B., McGowan, C H., Lenaers, G., Jones, R and Russell, P. (1991) EMBO J. 10, 4301-4309
12. Strausfeld, U., Labbe, J. C., Fesquet, D., Cavadore, J C., Picard, A., Sadhu, K., Russell, P., and Doree, M. (1991) Nature 351, 242-245
13. Lee, M. S., Ogg, S., Xu, M., Parker, L L., Donoghue, D. J, Maller, J. L., and Piwnica-Worms, H. (1992) Mol. Biol. Cell 3, 73-84
14. Sadhu, K., Reed, S. I., Richardson, H., and Russel, P. (1990) Proc. Natl Acad. Sci. U. S. A. 87, 5130-5143
15. Galaktionov, K., and Beach, D (1991) Cell 67, 1181-1194
16. Strausfeld, U., Fernandez, A, Capony. J. P., Girard, F , Lautredou, N., Derancourt, J , Labbe, J C., and Lamb, N J C. (1994) J Biol. Chem. 269, 5989-6000
17. Hoffmann, L. Draetta, G., and Karsenti, E. (1994) EMBO J. 13, 4302-4310
18. Jinno, S., Suto, K., Nagata, A., Igarashi, M., Kanaoka, Y., Nojima, H., and Okayama, H. (1994) EMBO J. 13, 1549-1556
19. Kumagai, A., and Dunphy, W. G. (1992) Cell 70, 139-151
20. Hoffmann, I., Clarke, P R., Marcote, M J., Karsenti, E , and Draetta, G (1993) EMBO J. 12, 53-63
21. Streuli, M., Krueger, N. X , Tsai, A Y , and Saito, H (1989) Proc. Natl. Acad. Sci U S A. 86, 8698-8702
22. Walton, K. M , and Dixon, J E. (1993) Annu. Rev. Biochem 62, 101-102
23. Zhang, Z Y., Thieme-Sefler, A. M., Maclean, D., McNamara, D. J., Dobrusin, E. M., Sawyer, T. K., and Dixon, J. E (1993) Proc Natl. Acad. Sci. U. S A. 90, 4446-4450
24. Zhang, Z. Y., and Dixon, J. E. (1993) Biochemistry 32, 9340-9345
25. Zhang, Z. Y., and Dixon, J. E. (1994) Adv Enzymol Relat. Areas Mol. Biol 68, 1-36
26. Zhang, Z. Y., Wang, Y., and Dixon, J E. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1624-1627
27. Zhou, G , Denu, J. M , Wu, L., and Dixon, J E. (1994) J. Biol. Chem. 269, 28084-28090
28. Barford, D , Flint, A. J., and Tonks, N. K. (1994) Science 263, 1397-1404
29. Logan, T., Zhou, M. M., Nettesheim, D. G , Meadows, R. P., Van Etten, R. L., and Feski, S. W. (1994) Biochemistry 33, 11087-11096
30. Su, X. D., Taddel, N., Stefani, M., Ramponi, G., and Nordlund, P. (1994) Nature 370, 575-578
31. Jia, Z. C., Barford, D., Flint, A. J., and Tonks, N. (1995) Science 268, 1754-1758
32. Denu, J M., Zhou, Y. G., and Dixon, J. E. (1995) Biochemistry 34, 3396-3403
33. Stuckey, J. A., Schubert, H. L., Fauman, E. B., Zhang, Z. Y., Dixon, J. E., and Saper, M. A. (1994) Nature 370, 571-575
34. Higuchi, R. B , Krummel, B., and Saiki, R. K. (1988) Nucleic Acids Res. 16, 7351-7367
35. Studier, W F., Rosenberg, A. H., Dunn, J. J., and Dubendorff, J. W. (1990) Methods Enzymol 185, 60-89
36. Pagano, M., Pepperkok, R., Verde, F., Ansorge, W., and Draetta, G. (1992) EMBO J. 11, 961-971
37. Laemmli, U. K (1970) Nature 227, 680-685
38. Elledge, S. J., and Spottswood, M. R. (1991) EMBO J. 10, 2653-2659
39. Tsai, A Y., Itoh, M., Streuli, M., Thai, T., and Saito, H. (1991) J. Biol. Chem. 266, 10534-10543
40. Gu, Y., Rosenblatt, J., and Morgan, D. O. (1992) EMBO J. 11, 3995-4005
41. Terada, Y , Tatska, M., Jinno, S., and Okayama, H. (1995) Nature 376, 358-362
42. Dulic, V., Lees, E., and Reed, S. I. (1992) Science 257, 1958-1961
43. Millar, J , McGowan, C., Jones, R., Sadhu, K., Bueno, A., Richardson, H. and Russell, P. (1991) Cold Spring Harb. Symp. Quant. Biol. 56, 577-584
44. Vernet, T., Khouri, H. E., Laflamme, P., Tessier, D. C., Musil, R., Gour-Salin, B. J., Storer, A C., and Thomas, D. Y. (1991) J. Biol Chem. 266, 21451-21457
45. Polasko-Lapat, L., Maley, G. F., and Maley, F. (1990) Biochemistry 29, 9561-9572
46. Climie, S., Ruiz-Perez, L., Gonzalez-Pacanowska, D., Prapunwattana, P., Cho, S. W., Stroud, R., and Santi, D. V (1990) J Biol. Chem. 265, 18776-18779
47. Wyszynski, M. W., Gabbara, S., Kubareva, E. A., Romanova, E. A., Oretskaya, T. S., Gromova, E. S., Shabarova, Z. A. and Bhagwat, A. S. (1993) Nucleic Acids Res. 21, 295-301
48. Nurse, P. (1975) Nature 256, 547-551
49. Fantes, P. (1979) Nature 279, 428-430
50. Russell, P., and Nurse, P. (1986) Cell 45, 145-153
51. Millar, J. B., Blevitt, J., Gerace, L., Sadhu, K., Featherstone, C , and Russell, P. (1991) Proc. Natl Acad. Sci. U S. A. 88, 10500-10504
52. Nagata, A., Igarashi, M., Jinno, S., Suto, K., and Okayama, H. (1991) New Biol. 3, 959-968
53. Millar, J. B. A., and Russell, P. (1992) Cell 68, 407-410
54. Ducommun, B., Draetta, G., Young, P., and Beach, D. (1990) Biochem. Biophys. Res. Commun. 167, 301-309
55. Moreno, S., and Nurse, P. (1991) Nature 351, 194
56. Galaktionov, K., Jessus, C., and Beach, D. (1995) Genes & Dev. 9, 1046-1058