Stereotaxic summation analysis of human cerebral benzodiazepine binding maps

Journal of Cerebral Blood Flow and Metabolism

Volumn 16, Issue 3, 1996, Pages 409-417

  Frey, K A ^a   Minoshima, S ^b   Koeppe, R A ^b   Kilbourn, M R ^b   Berger, K L ^b   Kuhl, D E ^b  

^a UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

^b NONE

Author keywords

Benzodiazepine receptor; Flumazenil; Image analysis

Indexed keywords

BENZODIAZEPINE; CARBON 11; FLUMAZENIL;

ADULT; ARTICLE; BINDING SITE; BRAIN MAPPING; CALCULATION; CLINICAL TRIAL; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; LIGAND BINDING; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOISOTOPE DISTRIBUTION; SPATIAL SUMMATION; STEREOTAXIC SURGERY;

EID: 0029981379     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199605000-00007     Document Type: Article

References (35)

1. Adler RJ, Hasofer AM (1976) Level crossings for random fields. Ann Probabil 4:1-12
2. Barrett G (1986) Analytic techniques in the estimation of evoked potentials. In: Handbook of Electrophysiology and Clinical Physiology, Vol. 2: Clinical Applications of Computer Analysis of EEC and Other Neurophysiologic Signals (Lopes da Silva FH, van Leeuwen WS, Rémond A, eds), Amsterdam, Elsevier, pp 311-333
3. Beydoun A, Morrow TJ, Shen JF, Casey KL (1993) Variability of laser-evoked potentials: attention, arousal and lateralized differences. Electroencephalogr Clin Neurophysiol 88:173-181
4. Cho K, Frey KA, Minoshima S, Ishihara M, Kuhl DE (1994) Diagnostic criteria for Alzheimer's disease based on [F-18]FDG cerebral metabolic deficits. J Nucl Med 35:93P
5. Efron B (1982) The Jackknife, the Bootstrap, and other Resampling Plans. Philadelphia, Society for Industrial and Applied Mathematics, pp 5-6
6. Evans AC, Marrett S, Torrescorzo J, Ku S, Collins L (1991) MRI-PET correlative analysis using a volume of interest (VOI) atlas. J Cereb Blood Flow Metab 11:A69-A78
7. Fox PT, Raichle ME (1984) Stimulus rate dependence of regional cerebral blood flow in human striate cortex, demonstrated with positron emission tomography. J Neurophysiol 51: 1109-1121
8. Fox PT, Perlmutter JS, Raichle ME (1985) A stereotactic method of anatomical localization for positron emission tomography. J Comput Assist Tomogr 9:141-153
9. Fox PT, Mintun MA, Reiman EM, Raichle ME (1988) Enhanced detection of focal brain responses using intersubject averaging and change distribution analysis of subtracted PET images. J Cereb Blood Flow Metab 8:642-653
10. Frey KA, Holthoff VA, Koeppe RA, Jewett DM, Kilbourn MR, Kuhl DE (1991) Parametric in vivo imaging of benzodiaze- pine receptor distribution in human brain. Ann Neurol 30: 663-672
11. Friston KJ, Frith CD, Liddle PF, Frackowiack RSJ (1991) Comparing functional (PET) images: The assessment of significant changes. J Cereb Blood Flow Metab 11:690-699
12. Gevins AS, Cutillo BA (1986) Signals of cognition. In: Handbook of Electrophysiology and Clinical Physiology, Vol. 2: Clinical Applications of Computer Analysis of EEG and Other Neurophysiologic Signals (Lopes da Silva FH, van Leeuwen WS, Rémond A, eds), Amsterdam, Elsevier, pp 335-381
13. Henry TR, Frey KA, Sackellares JC, Gilman S, Koeppe RA, Brunberg JA, Ross DA, Berent S, Young AB, Kuhl DE (1993) In vivo cerebral metabolism and central benzodiazepine receptor binding in temporal lobe epilepsy. Neurology 43:1998-2006
14. Ishihara M, Cameron O, Minoshima S, Drury I, Kuhl DE, Frey KA (1994) PET determinations of benzodiazepine receptor occupancy by unlabeled drugs. J Nucl Med 35:141P
15. 11C]flumazenil kinetics for the estimation of ligand transport rate and receptor distribution using positron emission tomography. J Cereb Blood Flow Metab 11:735-744
16. 11C]Tropanyl benzilate binding to muscarinic cholinergic receptors: methodology and kinetic modeling alternatives. J Cereb Blood Flow Metab 14:85-99
17. Kuhl DE, Koeppe RA, Fessler JA, Minoshima S, Ackermann RJ, Carey JE, Gildersleve DL, Frey KA, Wieland DM (1994) In vivo mapping of cholinergic neurons in the human brain using SPECT and IBVM. J Nucl Med 35:405-410
18. Lopes da Silva F (1987) Event-related potentials: methodology and quantification. In: Electroencephalography: Basic Principles, Clinical Applications and Related Fields (Niedermeyer E, Lopes da Silva F, eds), Baltimore, Urban & Schwarzenberg, pp 763-772
19. Minoshima S, Berger KL, Lee KS, Mintun MA (1992) An automated method for rotational correction and centering of three-dimensional functional brain images. J Nucl Med 33: 1579-1585
20. Minoshima S, Frey KA, Henry TR, Koeppe RA, Sackellares JC, Kuhl DE (1993a) Regional alteration of benzodiazepine receptor distribution in refractory temporal lobe epilepsy revealed by group averaging techniques. J Nucl Med 34:22P-23P
21. 11C]flumazenil distribution in the human brain. J Cereb Blood Flow Metab 13:8411
22. Minoshima S, Koeppe RA, Fessler JA, Mintun MA, Berger KL, Taylor SF, Kuhl DE (1993c) Integrated and automated data analysis method for neuronal activation studies using [O-15]water PET. Proceedings of PET '93 Akita: Quantification of Brain Function, Tracer Kinetics and Image Analysis in Brain PET, Amsterdam, Elsevier, pp 409-415
23. Minoshima S, Koeppe RA, Mintun MA, Berger KL, Taylor SF, Frey KA, Kuhl DE (1993d) Automated detection of the intercommissural (AC-PC) line for stereotactic localization of functional brain images. J Nucl Med 34:322-329
24. Minoshima S, Koeppe RA, Frey KA, Kuhl DE (1994a) Anatomical standardization: linear scaling and nonlinear warping of functional brain images. J Nucl Med 35:1528-1537
25. Minoshima S, Koeppe RA, Mukhopadhyay S, Jewett D, Kuhl DE, Kilbourn MR, Frey KA (1994b) Equilibrium measurement of [C-11]raclopride distribution volume in the brain using a continuous infusion technique. J Nucl Med 35:140P
26. Mintun MA, Raichle ME, Kilbourn MR, Wooten GF, Welch MJ (1984) A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography. Ann Neural 15:217-227
27. 11C Ro 15-1788 binding to the human neocortex using positron emission tomography. Hum Psychopharmacol 4:21-31
28. Rice JA (1988) Mathematical Statistics and Data Analysis, Belmont, California, Wadsworth & Brooks/Cole, p 169
29. Talairach J, Tournoux P (1988) A Co-Planar Stereotaxic Atlas of a Human Brain. Stuttgart, Thieme-Verlag
30. Vander Borght TM, Desmond TJ, Kilbourn MR, Albin RL, Koeppe RA, Kuhl DE, Frey KA (1994) Evaluation of methoxytetrabenazine as an in vivo tracer of monoamine nerve terminal integrity. J Nucl Med 35:121P
31. 2, F and t fields. Adv Appl Prob 26:13-42
32. Worsley KJ, Evans AC, Marrett S, Neelin P (1992) A three-dimensional analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab 12:900-918
33. Worsley KJ, Evans AC, Marrett S, Neelin P (1993) Detecting and estimating the regions of activation in CBF activation studies in human brain. In: Quantification of Brain Function: Tracer Kinetics and Image Analysis in Brain PET (Uemura U, Lassen N, Jones T, Kanno I, eds), Amsterdam, Elsevier Science Publishers, pp 535-548
34. Zezula J, Cortes R, Probst A, Palacios JM (1988) Benzodiazepine receptor sites in the human brain: autoradiographic mapping. Neuroscience 25:771-795
35. Zubieta JK, Frey KA, Koeppe RA, Kuhl DE (1993) Quantification of muscarinic receptors in vivo with [C-11]NMPB and PET: distinction of ligand delivery and binding. J Nucl Med 34:108P