Sensitization and desensitization to capsaicin and menthol in the oral cavity: Interactions and individual differences

Physiology and Behavior

Volumn 59, Issue 3, 1996, Pages 487-494

  Cliff, Margaret A ^a   Green, Barry G ^b  

^a AGRICULTURE AND AGRI FOOD CANADA   (Canada)

^b MONELL CHEMICAL SENSES CENTER   (United States)

Author keywords

Capsaicin; Cold; Desensitization; Human; Irritation; Menthol; Oral; Sensitization

Indexed keywords

CAPSAICIN; IRRITANT AGENT; MENTHOL;

ADULT; ARTICLE; COLD SENSATION; CONTROLLED STUDY; CROSS ALLERGY; DESENSITIZATION; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; MALE; MOUTH CAVITY; NORMAL HUMAN; PRIORITY JOURNAL; SENSITIZATION; SENSORY NERVE; TOPICAL DRUG ADMINISTRATION;

EID: 0029981254     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/0031-9384(95)02089-6     Document Type: Article

References (40)

1. Armstrong, D.; Dry, R. M. L.; Keele, C. A.; Markham, J. W. Observations on chemical excitants of cutaneous pain in man. J. Physiol. 120:326-351; 1953.
2. Barthó, L.; Stein, C.; Herz, A. Involvement of capsaicin-sensitive neurones in hyperalgesia and enhanced opioid antinociception in inflammation. Naunyn Schmiedeberg's Arch. Pharmacol. 342:666-670; 1990.
3. Baumann, T. K.; Simone, D. A.; Shain, C. N.; LaMotte, R. H. Neurogenic hyperalgesia: The search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia. J. Neurophysiol. 66:212-227; 1991.
4. Bini, G.; Cruccu, G.; Hagbarth, K.-E.; Shady, W.; Torebjork, E. Analgesic effect of vibration and cooling on pain induced by intraneural electrical stimulation. Pain 18:239-248; 1984.
5. Borg, G. Psychophysical scaling with applications in physical work and the perception of exertion. Scand. J. Work Environ. Health 16:55-58; 1990.
6. Buck, S. H.; Burks, T. F. The neuropharmacology of capsaicin: Review of some recent observations. Pharmacol. Rev. 38:179-226; 1986.
7. Chapman, C. E. Can the use of physical modalities for pain control be rationalized by the research evidence?. Can. J. Physiol. Pharmacol. 69:704-712; 1991.
8. Cliff, M. A.; Green, B. G. Sensory irritation and coolness produced by menthol: Evidence for selective desensitization of irritation. Physiol. Behav. 56:1021-1029; 1994.
9. Craft, R. M.; Porreca, F. Treatment parameters of desensitization to capsaicin. Life Sci. 51:1767-1775; 1992.
10. Craig, A. D.; Bushnell, M. C. The thermal grill illusion: Unmasking the burn of cold pain. Science 265:252-255; 1994.
11. Dodt, E.; Skouby, A. P.; Zotterman, Y. The effect of cholinergic substances on the discharge from thermal receptors. Acta Physiol. Scand. 28:101-114; 1953.
12. Foster, R. W.; Ramage, A. G. The action of some chemical irritants on somatosensory receptors of the cat. Neuropharmacology 20:191-198; 1981.
13. Garcia Medina, M. R.; Cain, W. S. Bilateral integration in the common chemical sense. Physiol. Behav. 29:349-353; 1982.
14. Gilmore, M. M.; Green, B. G. Sensory irritation and taste produced by NaCl and citric acid: Effects of capsaicin desensitization. Chem. Senses 18:257-272; 1993.
15. Green, B. G. Sensory interactions between capsaicin and temperature. Chem. Senses 11:371-382; 1986.
16. Green, B. G. Spatial and temporal factors in the perception of ethanol irritation on the tongue. Percept. Psychophys. 44:108-116; 1988.
17. Green, B. G. Capsaicin sensitization and desensitization on the tongue produced by brief exposures to a low concentration. Neurosci. Lett. 107:173-178; 1989.
18. Green, B. G. Capsaicin cross-desensitization on the tongue: Psychophysical evidence that oral chemical irritation is mediated by more than one sensory pathway. Chem. Senses 16:675-689; 1991.
19. Green, B. G. Temporal characteristics of capsaicin sensitization and desensitization on the tongue. Physiol. Behav. 49:501-505; 1991.
20. Green, B. G. The effects of temperature and concentration on the perceived intensity and quality of carbonation. Chem. Senses 17:435-450; 1992.
21. Green, B. G. Evidence that removal of capsaicin accelerates desensitization on the tongue. Neurosci. Lett. 150:44-48; 1993.
22. Green, B. G.; Shaffer, G. S. The sensory response to capsaicin during repeated topical exposures: Differential effects on sensations of itching and pungency. Pain 53:323-334; 1993.
23. Green, B. G.; Shaffer, G. S.; Gilmore, M. M. Derivation and evaluation of a semantic scale of oral sensation magnitude with apparent ratio properties. Chem. Senses 18:683-702; 1993.
24. Hellekant, G. Action and interaction of ethyl alcohol and some other substances on the receptors of the tongue. In: Hayashi, T., ed. Olfaction and Taste II. New York: Pergamon Press; 1967:465-479.
25. Hellekant, G. The effect of menthol on taste receptors. Acta Physiol. Scand. 76:361-368; 1969.
26. Hensel, H.; Zotterman, Y. The effect of menthol on thermoreceptors. Acta Physiol. Scand. 24:27-34; 1951.
27. Holzer, P. Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol. Rev. 43:143-201; 1991.
28. Jancso, N. Role of the nerve terminals in the mechanism of inflammatory reactions.. Bull. Millard Fillmore Hosp. 7:53-77; 1960.
29. Jancso, N.; Jancso-Gabor, A.; Takats, I. Pain and inflammation induced by nicotine, acetylcholine and structurally related compounds and their prevention by desensitizing agents.. Acta Physiol. Acad. Sci. Hung. 19:113-132; 1961.
30. Karrer, T.; Bartoshuk, L. Capsaicin desensitization and recovery on the human tongue. Physiol. Behav. 49:757-764; 1991.
31. Kenins, P. Responses of single nerve fibres to capsaicin applied to the skin. Neurosci. Lett. 29:83-88; 1983.
32. Kilo, S.; Schmelz, M.; Koltzenburg, M.; Handwerker, H. O. Different patterns of hyperalgesia induced by experimental inflammation in human skin. Brain 117:385-396; 1994.
33. LaMotte, R. H.; Shain, C. N.; Simone, D. A.; Tsai, E.-F. P. Neurogenie hyperalgesia: Psychophysical studies of underlying mechanisms. J. Neurophysiol. 66:190-211; 1991.
34. Maggi, C. A. Capsaicin and primary afferent neurons: From basic science to human therapy. J. Auton. Nerv. Syst. 33:1-14; 1991.
35. Nasrawi, C. W.; Pangborn, R. M. Temporal effectiveness of mouth-rinsing on capsaicin mouth-burn. Physiol. Behav. 47:617-623; 1990.
36. Sizer, F.; Harris, N. The influence of common food additives and temperature on threshold perception of capsaicin. Chem. Senses 10:279-286; 1985.
37. Stevens, D. A.; Lawless, H. T. Enhancement of responses to sequential presentation of oral chemical irritants. Physiol. Behav. 39:63-65; 1987.
38. Swandulla, D.; Carbone, E.; Shafer, K.; Ix, H. D. Effect of menthol on two types of calcium currents in cultured sensory neurons of vertebrates. Pflugers Arch. 409:52-59; 1987.
39. Swandulla, D.; Schafer, K.; Ix, H. D. Calcium channel current inactivation is selectively modulated by menthol. Neurosci. Lett. 68:23-28; 1986.
40. Szolcsanyi, J. A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain. J. Physiol. (Paris) 73:251-259; 1977.