The Saccharomyces cerevisiae RTG2 gene is a regulator of aconitase expression under catabolite repression conditions

Genetics

Volumn 144, Issue 3, 1996, Pages 893-903

  Vélot, Christian ^a   Haviernik, Peter ^a   Lauquin, Guy J M ^b  

^a Institut de Biochimie et Genetique Cellulaires   (France)

^b Physics and Informatics   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITATE HYDRATASE;

AEROBIC METABOLISM; ALLELE; ARTICLE; ENZYME INDUCTION; FUNGUS GROWTH; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; SACCHAROMYCES CEREVISIAE;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0029981135     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (69)

1. BÉCAM, A.-.M., Y. JIA, P. P. SI.ONIMSKI and C. J. HERBERT, 1995 The CIT3gcnc olS. cerevisiaeencodes a second mitochondrial isoform of citrate synthase, p. 300 in Abstracts of the 17th International Conference on Yeast Genetics and Molecular Iliology. Lisbon, Portugal.
2. BEGCJS, J. D., 1978 Transformation of yeast by a replicating hybrid plasmid. Nature 275: 104-109.
3. BERBEN, G., J. DUMOXT, V. GIU.IQUKT, P.-A. BOU.E and F. HII.C.ER, 1991 The YPp plasmids: a uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae. Yeast 7: 475-477.
4. BURGERS, P. M.J., and K.J. PERCIVAI., 1987 Transformation of yeast spheroplasts without cell fusions. Anal. Biochem. 163: 391-397.
5. CHELSTOWSKA, A., and R. A. Burow, 1995 RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisomal proteins. J. Biol. Chem. 270: 18141-18146.
6. COOPER, T. G, 1982 Nitrogen metabolism in Saccharomyces cerevisiae, pp. 39-99 in The Molecular Biology of the Yeast Saccharomyces, edited byj. N. STRATHERN, E. \V. JONES andj. R. BROACH. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
7. Curp, J. R., and L. McAl.iSTER-HENN, 1991 NAD+-dependent isocitrate dehydrogenase: cloning, nucleotide sequence, and disruption of the IDHZgcne from Saccharomyces cerevisiae.]. Biol. Chem. 266: 22199-22205.
8. DE BEI.I.IS, L., P. PICCIAREU.I, L. PISTEI.U and A. AI.PI, 1990 Localisation of glyoxylate cycle mark'er enzymes in peroxisomes of senescent leaves and green cotyledons. Planta 180: 435-439.
9. DUNTZE, W., D. NEUMANN, J. M. GAXCEDO, W. ATZPODIEN and H. HOLZER, 1969 Studies on the regulation and localization of the glyoxylate cycle enzymes in Saccharomyces cerevisiae. Eur. J. Biochem. 10: 83-89.
10. FANSI.ER, B., and J. M. LOVENSTEIX, 1969 Aconitase from pig heart. Methods Enzymol. 13: 26-31.
11. FEIXBERG, A. P., and B. VOGELSTEIN, 1984 A technic for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 137: 266-267.
12. FINK, G. R., 1970 Biochemical genetics of yeast. Methods Enzymol. 17: 59-78.
13. FOLCII, J.-L., A. ANTARA.MIAN, L. RODRIGUEZ, A. BRAVO, A. BRUNNER et al., 1989 Isolation and characterization of a Saccharomyces cerevisiae mutant with impaired glutamate synthase activity. J. Bacteriol. 171: 6776-6781.
14. FORSBURG, S. L., and L. GUARENTE, 1988 Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: a HAP2-HAP3 responsive site. Mol. Cell. Biol. 8: 647-657.
15. FORSBURG, S. L., and L. GUARENTE, 1989 Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer. Genes Dev. 3: 1166-1178.
16. GANGLOFF, S. P., 1990 Ph.D. thesis. University of Aix-Marseille II. Marseille.
17. GANGLOFF, S. P., D. MARGUET and G. J.-M. LAUQUIN, 1990 Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate. Mol. Cell. Biol. 10: 3551-3561.
18. GIETZ, D., A. ST.-JEAN, R. A. WOODS and R. H. SCHIESTL, 1992 Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20: 1425.
19. GUARENTE, L., 1983 Yeast promoters and lacZ fusions designated to study expression of cloned genes in yeast. Methods Enzymol. 101: 181-191.
20. GUARENTE, L., B. LAI.ONDE, P. GIFFORD and E. AIANI, 1984 Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae. Cell 36: 503-511.
21. HANAIIAN, D., and M. MESF.I.SON, 1980 Plasmicl screening at high colony density. Gene 10: 63-67.
22. HANSON, R. S., and D. P. Cox, 1967 Effect of different nutritional conditions on the synthesis of tricarboxylic acid cycle enzymes. J. Bacteriol. 93: 1777-1787.
23. ITO, H., Y. FUKUDA, K. MURATA and A. KIMURA, 1983 Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153: 163-168.
24. JONES, E. W., and G. R. FINK, 1982 Regulation of amino acid and nucleotide biosynthesis in yeast, pp. 181-299 in The Molecular Biology of the Yeast Saccharomyces, edited byj. N. STRATI IER.X, E. W. JONES and J. R. BROACH. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
25. KAWAMOTO, S., A. TANAKA, M. YAMA.MURA, Y. TERANISHI, S. FUKUI et al., 1977 Microbody of n-alkane-grown yeast. Enzyme localization in the isolated microbody. Arch. Microbiol. 112: 1-8.
26. KIM, K.-S., M. S. ROSENKRANTZ and L. GUARENTE, 1986 Saccharomyces cerevisiae contains two functional citrate synthase genes. Mol. Cell. Biol. 6: 1936-1942.
27. KISPAL, G., C. T. EVANS, C. MALLOY and P. A. SRERE, 1989 Metabolic studies of citrate synthase mutants of yeast: a change in phenotype following transformation with an inactive enzyme. J. Biol. Chem. 264: 11204-11210.
28. KOONIN, E. V., 1994 Yeast protein controlling inter-organelle com
29. Munication is related to bacterial pliosphatascs containing the Hsp70-t)pe ATP-bincling domain. Trends Biochem. Sei. 19: 156-157.
30. KREBS, H. A., and j. M. LOWENSTEIN, 1960 The tricarboxylic acid cycle, pp. 129-303 in Metabolic Pathways, edited by D. M. GREENBERG. Academic Press, Inc., New York.
31. LEWIN, A. S., V. HIXES and G. M. SMALL, 1990 Citrate synthase encoded by the CIT2 gene of Saccharomyces cerevisiae is peroxisomal. Mol. Cell. Biol. 10: 1399-1405.
32. LIAO, X., and R. A. Burow, 1993 RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72: 61-71.
33. LIAO, X., \V. C. SMALL, P. A. SRERE and R. A. Burow, 1991 Intramitochondrial functions regulate nonmitochondrial citrate synthase (C1T2) expression in Saccharomyces cerevisiae. Mol. Cell. Biol. 11: 38-46.
34. MAGASANIK, B., 1992 Regulation of nitrogen utilization, pp. 283317 in The Molecular and Cellular Biology of the Yeast Saccharomyces, edited by E. W. JONES, J. R. PRINGLE and J. R. BROACH. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
35. MANIATIS, T., E. F. FRITSCII and J. SAMBROOK, 1982 Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
36. McAi.iSTER-HENN, L., and L. M. THOMPSON, 1987 Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase. J. Bacteriol. 169: 5157-5166.
37. McCAMMON, M. T., M. VEENHUIS, S. B. TRAPP andj. M. GOODMAN, 1990 Association of glyoxylate and beta-oxidation enzymes with peroxisomes of Saccharomyces cerevisiae. J. Bacteriol. 172: 5816-5827.
38. MCîS'ABB, D. S., Y. XING and L. GUARE.NTE, 1995 Cloning of yeast HAP5: a novel subunit of a heterotrimeric complex required for CCAAT binding. Genes Dev. 9: 47-58.
39. MIOOEI.HOVEN, W. J., 1964 The pathway of arginine breakdown in Saccharomyces cerevisiae. Biochim. Biophys. Acta 93: 650-652.
40. MII.I.ER, J. H., 1972 Experiments in Molecular Genetics. Cold Spring Harbor laboratory Press, Cold Spring Harbor, NY.
41. MILLER, S. M., and B. MAGASANIK. 1990 Role of NAD-linked glutamate dehydrogcnase in nitrogen metabolism in Saccharomyces cerevisiae. J. Bacteriol. 172: 4927-4935.
42. MITCHELI, A. P., 1985 The G/JV7 locus of Saccharomyces cerevisiae encodes glutamine synthetase. Genetics 111: 243-258.
43. MITCHELI., A. P., and B. MAGASANIK, 1983 Purification and properties of glutamine synthctase from Saccharomyces cerevisiae.]. Biol. Chem. 258: 119-124.
44. MYERS, A. M., A. TZAGOI.OFF, D. M. KINNEY and C. J. LUSTY, 1986 Yeast shuttle and integrative vectors with multiple cloning sites suitable for construction of lacZ fusions. Gene 45: 299-310.
45. OGUR, M., L. COKER and S. OGUR, 1964 Glutamate auxotrophs in Saccharomyces. I. The biochemical lesion in the glt-1 mutants. Biochem. Biophys. Res. Commun. 14: 193-197.
46. OGUR, M., A. ROSHANMANESH and S. OGUR, 1965 Tricarboxylic acid cycle mutants in Saccharomyces cerevisiae: comparison of independently derived mutants. Science 147: 1590.
47. OLESEN.J., S. HAIIN and L. GUARENTE, 1987 Yeast HAP2 and HAP3 activators botli bind to the CYC1 upstream activation site, UAS2, in an interdependent manner. Cell 51: 953-961.
48. OLSON, M. V., J. E. DUTCHIK, M. Y. GRAHAM, G. M. BRODEUR, C. HELMS et al., 1986 Random-clone strategy for genomic restriction mapping in yeast. Proc. Natl. Acad. Sei. USA 83: 7826-7830.
49. REITZER, L. J., and B. MAGASANIK, 1987 Ammonia assimilation and the biosynthesis of glutamine, glutamate, aspartate, asparagine, L-alaninc, and D-alaninc, p. 302-320 in Escherichia coli and Salmonella lyphimurium, Cellular and Molecular Biology, Vol. 1, edited by F. C. NEIDHARDT.J. L. INCRAHAM, K. BROOKS Low, B. MAGASANIK, M. SciLVECHTERrt al. American Society for Microbiology, Washington, DC.
50. REYNOLDS, S.J., and S. M. SMITH, 1995 The isocitrate lyase of cucumber: isolation, characterization and expression in cotyledons following seed germination. Plant Mol. Biol. 27: 487-497.
51. RILES, L., J. E. DUTCHIK, A. BAKTIIA, B. K. MCCAULEY, E. C. THAYER et al., 1993 Physical maps of the six smallest chromosomes of Saccharomyces cerniisiaeM a resolution of 2.6 kilobase pairs. Genetics 134:81-150.
52. ROSE, I. A., and E. L. O'CoNNEl.L, 1967 Mechanism of aconitase action. J. Biol. Chem. 242: 1870-1879.
53. ROSE, M. D., P. NoviCK, J. H. THOMAS, D. BOTSTEIN and G. R. FINK, 1987 A Saccharomyces cerevisiae genomic plasmid bank based on a centromeric-containing shuttle vector. Gene 60: 237-243.
54. ROSEXKRANTZ, M. S., D. \V. DiNGMAN and A. L. SONENSHEIN, 1985 Bacillus subtilis dlB gene is regulated synergistically by glucose and glutamine. J. Bacteriol. 164: 155-164.
55. ROSENKRANTZ, M. S., T. AIAM, K. Km, B. J. CIARK, P. A. SRERE et al., 1986 Mitochondrial and nonmitochondrial citrate synthase in Saccharomyces cerevisiae are encoded by distinct homologous genes. Mol. Cell. Biol. 6: 4509-4515.
56. SäNGER, F., S. NiCKl.EN and A. R. GOUI.SOX, 1977 DMA sequencing with chain termination inhibitors. Proc. Natl. Acad. Sei. USA 74: 5463-5467.
57. SIIERMAN, F., G. R. FINK and J. B..HICKS, 1986 Methods in Yeast Genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NT.
58. SIKORSKI, R. S., and P. HIETER, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
59. SMAI.L, W. C., R. D. BRODEUR, A. SANDOR, N. FEDOROVA, G. Li et al., 1995 Enzymatic and metabolic studies on retrograde regulation mutants of yeast. Biochemistry 34: 5569-5576.
60. SMITH, P. K., R. I. KROIIN, G. T. HERMAXSOX, A. K. MALLIA, F. H. GARTNER el al., 1985 Measurement of protein using bicinchoninic acid. Anal. Biochem. 150: 76-85.
61. SOUTHERN, E. M., 1975 Detection of specific sequences among DN'A fragments separated by gel electrophoresis. J. Mol. Biol. 98: 503-517.
62. TOLBERT, N. E., 1981 Metabolic pathways in peroxisomes and glyoxysomes. Annu. Rev. Biochem. 50: 133-157.
63. TREI.EASE, R. N., 1984 Biogenesis of glyoxysomes. Annu. Rev. Plant Physiol. 35: 321-347.
64. Twice, A. J., and D. SHERRATT, 1980 Trans-complemen table copy number mutants of plasmid colEl. Nature 283: 216-218.
65. VII.IAFRANCA, J. J., and A. S. MILDVAN, 1971 The mechanism of aconitase action. J. Biol. Chem. 246: 772-779.
66. WALES, D. S., T. G. CARTLEDGE and D. LLOYD, 1980 Effects of glucose repression and anaerobiosis on the activities and subcellular distribution of tricarboxylic acid cycle and associated enzymes in Saccharomyces carlsbergensis. J. Gen. Microbiol. 116: 93-98.
67. WANNER, G., and R. R. THEIMER, 1982 Two types of microbodies in Xeurospom croisa. Ann. NY Acad. Sei. 386: 269-284.
68. WiAME,J.-M., M. GRENSON and H. N. ARST, 1985 Nitrogen catabolite repression in yeasts and filamentous fungi. Adv. Microb. Physiol. 26: 1-87.
69. ZIMMERMANN R., and W. NEUPERT, 1980 Biogenesis of glyoxysomes. Eur.J. Biochem. 112: 225-233.