메뉴 건너뛰기




Volumn 40, Issue 11, 1996, Pages 2637-2643

N-1-tert-butyl-substituted quinolones: In vitro anti-Mycobacterium avium activities and structure-activity relationship studies

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; PAZUFLOXACIN; PD 138926; PD 158804; PD 161314; PD 161315; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TOSUFLOXACIN; UNCLASSIFIED DRUG;

EID: 0029981122     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.11.2637     Document Type: Article
Times cited : (27)

References (22)
  • 1
    • 0025882895 scopus 로고
    • Recent developments in the field of quinolone antibacterial agents
    • Chu, D. T. W., and P. B. Fernandes. 1991. Recent developments in the field of quinolone antibacterial agents. Adv. Drug Res. 21:39-144.
    • (1991) Adv. Drug Res. , vol.21 , pp. 39-144
    • Chu, D.T.W.1    Fernandes, P.B.2
  • 2
    • 0028316927 scopus 로고
    • Structure-activity and structure-side-effect relationships for quinolone antibacterials
    • Domagala, J. M. 1994. Structure-activity and structure-side-effect relationships for quinolone antibacterials. J. Antimicrob. Chemother. 33:685-706.
    • (1994) J. Antimicrob. Chemother. , vol.33 , pp. 685-706
    • Domagala, J.M.1
  • 4
    • 0027462143 scopus 로고
    • Quinolone antibacterials containing the new 7-[3-(1-aminoethyl)-1-pyrrolidinyl] side chain: The effects of the 1-aminoethyl moiety and its stereochemical configurations on potency and in vivo efficacy
    • Domagala, J. M., S. E. Hagen, T. Joannides, J. S. Kiely, E. Labordo, and M. C. Schroeder. 1993. Quinolone antibacterials containing the new 7-[3-(1-aminoethyl)-1-pyrrolidinyl] side chain: the effects of the 1-aminoethyl moiety and its stereochemical configurations on potency and in vivo efficacy. J. Med. Chem. 36:871-882.
    • (1993) J. Med. Chem. , vol.36 , pp. 871-882
    • Domagala, J.M.1    Hagen, S.E.2    Joannides, T.3    Kiely, J.S.4    Labordo, E.5    Schroeder, M.C.6
  • 5
    • 0022633174 scopus 로고
    • New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay
    • Domagala, J. M., L. D. Hanna, C. L. Heifetz, M. P. Hutt, T. F. Mich, J. P. Sanchez, and M. Solomon. 1986. New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay. J. Med. Chem. 29:394-404.
    • (1986) J. Med. Chem. , vol.29 , pp. 394-404
    • Domagala, J.M.1    Hanna, L.D.2    Heifetz, C.L.3    Hutt, M.P.4    Mich, T.F.5    Sanchez, J.P.6    Solomon, M.7
  • 6
    • 0023885198 scopus 로고
    • 1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydto-4-oxo-3- quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials
    • Domagala, J. M., C. L. Heifetz, M. P. Hutt, T. F. Mich, J. B. Nichols, M. Solomon, and D. F. Worth. 1988. 1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydto-4-oxo-3- quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials. J. Med. Chem. 31:991-1001.
    • (1988) J. Med. Chem. , vol.31 , pp. 991-1001
    • Domagala, J.M.1    Heifetz, C.L.2    Hutt, M.P.3    Mich, T.F.4    Nichols, J.B.5    Solomon, M.6    Worth, D.F.7
  • 7
    • 0025726861 scopus 로고
    • Synthesis and biological activity of 5-alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic acids
    • Hagen, S. E., J. M. Domagala, C. L. Heifetz, and J. Johnson. 1991. Synthesis and biological activity of 5-alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic acids. J. Med. Chem. 34:1155-1161.
    • (1991) J. Med. Chem. , vol.34 , pp. 1155-1161
    • Hagen, S.E.1    Domagala, J.M.2    Heifetz, C.L.3    Johnson, J.4
  • 8
    • 0025057986 scopus 로고
    • New quinolone antibacterial agents. Synthesis and biological activity of 7-(3,3- Or 3,4-disubstituted-1-pyrrolidyl)quinoline-3-carboxylic acid
    • Hagen, S. E., J. M. Domagala, C. L. Heifetz, J. P. Sanchez, and M. Solomon. 1990. New quinolone antibacterial agents. Synthesis and biological activity of 7-(3,3- or 3,4-disubstituted-1-pyrrolidyl)quinoline-3-carboxylic acid. J. Med. Chem. 33:849-854.
    • (1990) J. Med. Chem. , vol.33 , pp. 849-854
    • Hagen, S.E.1    Domagala, J.M.2    Heifetz, C.L.3    Sanchez, J.P.4    Solomon, M.5
  • 9
    • 0021529312 scopus 로고
    • Artificial intelligence approach to structure-activity studies. Computer automated structure evaluation of biological activity of organic molecules
    • Klopman, G. 1984. Artificial intelligence approach to structure-activity studies. Computer automated structure evaluation of biological activity of organic molecules. J. Am. Chem. Soc. 106:7315-7321.
    • (1984) J. Am. Chem. Soc. , vol.106 , pp. 7315-7321
    • Klopman, G.1
  • 10
    • 0026778110 scopus 로고
    • MULTICASE: A hierarchical computer automated structure evaluation program
    • Klopman, G. 1992. MULTICASE: a hierarchical computer automated structure evaluation program. Quant. Struct.-Act. Relat. 11:176-184.
    • (1992) Quant. Struct.-Act. Relat. , vol.11 , pp. 176-184
    • Klopman, G.1
  • 11
    • 0029880891 scopus 로고    scopus 로고
    • Antimycobacterial quinolones: A comparative analysis of structure-activity and structure-cytotoxicity relationships
    • Klopman, G., D. Fercu, J.-Y. Li, H. S. Rosenkranz, and M. R. Jacobs. 1996. Antimycobacterial quinolones: a comparative analysis of structure-activity and structure-cytotoxicity relationships. Res. Microbiol. 147:86-96.
    • (1996) Res. Microbiol. , vol.147 , pp. 86-96
    • Klopman, G.1    Fercu, D.2    Li, J.-Y.3    Rosenkranz, H.S.4    Jacobs, M.R.5
  • 15
    • 0027254969 scopus 로고
    • Anti-Mycobacterium avium activity of quinolones: Structure-activity relationship studies
    • Klopman, G., S. Wang, M. R. Jacobs, and J. J. Ellner. 1993. Anti-Mycobacterium avium activity of quinolones: structure-activity relationship studies. Antimicrob. Agents Chemother. 37:1807-1815.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 1807-1815
    • Klopman, G.1    Wang, S.2    Jacobs, M.R.3    Ellner, J.J.4
  • 17
    • 0027162938 scopus 로고
    • Penetration of lipophilic agents with multiple protonation sites into bacterial cells: Tetracyclines and fluoroquinolones as examples
    • Nikaido, H., and D. G. Thanassi. 1993. Penetration of lipophilic agents with multiple protonation sites into bacterial cells: tetracyclines and fluoroquinolones as examples. Antimicrob. Agents Chemother. 37:1393-1399.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 1393-1399
    • Nikaido, H.1    Thanassi, D.G.2
  • 18
    • 0030041117 scopus 로고    scopus 로고
    • Structure-activity relationships of the quinolone antibacterials against mycobacteria: Effect of structural changes at N-1 and C-7
    • Renau, T. E., J. P. Sanchez, J. W. Gage, J. A. Denver, M. A. Shapiro, S. J. Gracheck, and J. M. Domagala. 1996. Structure-activity relationships of the quinolone antibacterials against mycobacteria: effect of structural changes at N-1 and C-7. J. Med. Chem. 39:729-735.
    • (1996) J. Med. Chem. , vol.39 , pp. 729-735
    • Renau, T.E.1    Sanchez, J.P.2    Gage, J.W.3    Denver, J.A.4    Shapiro, M.A.5    Gracheck, S.J.6    Domagala, J.M.7
  • 20
    • 0028693339 scopus 로고
    • Molecular mechanisms of DNA gyrase inhibition by quinolone antibacterials
    • Shen, L. L. 1994. Molecular mechanisms of DNA gyrase inhibition by quinolone antibacterials. Adv. Pharmacol. 29A:285-304.
    • (1994) Adv. Pharmacol. , vol.29 A , pp. 285-304
    • Shen, L.L.1
  • 21
    • 0021669296 scopus 로고
    • Inactivation of cytochrome P-450 and monoamine oxidase by cyclopropylamine
    • Tullman, R. H., and R. P. Hanzlik. 1984. Inactivation of cytochrome P-450 and monoamine oxidase by cyclopropylamine. Drug Metab. Rev. 15:1163-1182.
    • (1984) Drug Metab. Rev. , vol.15 , pp. 1163-1182
    • Tullman, R.H.1    Hanzlik, R.P.2
  • 22
    • 0023231360 scopus 로고
    • Broth microdilution testing of susceptibilities to 30 antimicrobial agents of Mycobacterium avium strains from patients with acquired immune deficiency syndrome
    • Yajko, D. M., P. S. Nassos, and W. K. Hadley. 1987. Broth microdilution testing of susceptibilities to 30 antimicrobial agents of Mycobacterium avium strains from patients with acquired immune deficiency syndrome. Antimicrob. Agents Chemother. 31:1579-1584.
    • (1987) Antimicrob. Agents Chemother. , vol.31 , pp. 1579-1584
    • Yajko, D.M.1    Nassos, P.S.2    Hadley, W.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.