Synthesis and antibacterial activity of 6-deoxysporeamicin A

Journal of Antibiotics

Volumn 49, Issue 5, 1996, Pages 493-495

  Faghih, Ramin ^a   Freiberg, Leslie ^a   Leonard, James ^a   Plattner, Jacob J ^a   Lartey, Paul A ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 DEOXYSPOREAMICIN A; MACROLIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

EID: 0029980887     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.493     Document Type: Article

References (10)

1. KIRST, H. A.: Structural modification of macrolide antibiotics. In Recent Progress in the Chemical Synthesis of Antibiotics. Eds., G. LUKACS & M. OHNO, pp. 39-63, Springer-Verlag, Heidelberg, 1990
2. LARTEY, P. A. & T. J. PERUN: Synthetic modifications of the erythromycin A macrolactone: Effects on antibacterial activity. In Studies in Natural Products Chemistry, Bioactive Natural Products (Part A), Volume 13, Eds. A. U. RAHMAN & F. Z. BASHA, pp. 155-185, Elsevier, Amsterdam 1993
3. LARTEY, P. A. & R. FAGHIH: Recent progress in the chemical modification of erythromycin. In Recent Progress in the Chemical Synthesis of Antibiotics and Related Microbial Products. Vol. 2, Ed., G. LUKACS, pp. 39-63, Springer-Verlag Heidelberg, 1993
4. LARTEY, P. A.; H. N. NELLANS & S. K. TANAKA: New developments in macrolides: Structures and antibacterial and prokinetic activities. In Advances in Pharmacology, Vol. 28, Ed. J. T. AUGUST, M. W. ANDERS, F. MURAD & J. T. COYLE, pp. 307-343, Academic Press, San Diego, 1994
5. FREIBERG, L. A.; C. M. EDWARDS, D. J. BACINO, L. L. KLEIN, R. STEPHENS, S. SPANTON & K. KIM: Synthesis of (9S,11S)-9-deoxo-12-deoxy-9,12-epoxyerythromycin A (A-63483) and related compounds, a new class of acid stable macrolide antibiotics. Program and Abstracts of the 29th. Intersci. Conf. on Antimicrob. Agents Chemother., No. 1028, p. 276, Houston, Sept. 17-20, 1989
6. YAGINUMA, S.; A. MORISHITA, K. ISHIZAWA, S. MUROFUSHI, M. HAYASHI & N. MUTOH: Sporeamicin A, a new macrolide antibiotic. I. Taxonomy, fermentation, isolation and characterization. J. Antibiotics 45: 599-606, 1992
7. MORISHITA, A.; K. ISHIZAWA, N. MUTOH, T. YAMAMOTO, M. HAYASHI & S. YAGINUMA: Sporeamicin A, a new macrolide antibiotic. II. Structure determination. J. Antibiotics 45: 607-612, 1992
8. MORISHITA, A.; N. MUTOH, K. ISHIZAWA, T. SUZUKI, S. YOKOIYAMA & S. YAGINUMA: Sporeamicin A, a new macrolide antibiotic. III. Biological properties. J. Antibiotics 45: 613-617, 1992
9. WEBER, J. M.; J. O. LEUNG, S. J. SWANSON, K. B. IDLER & J. B. MCALPINE: An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea. Science 252: 114-117, 1991
10. National Committee for Clinical Laboratory Standards: Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. M7-A, Vol. 5, No. 22, 1985