Inhibition of interleukin-6 synthesis in an animal model of septic shock by anti-C5a monoclonal antibodies

European Journal of Immunology

Volumn 26, Issue 5, 1996, Pages 1103-1109

  Höpken, Uta ^a   Mohr, Michael ^a   Strüber, Andreas ^a   Montz, Hildegard ^a   Burchardi, Hilmar ^a   Götze, Otto ^a   Oppermann, Martin ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

C5a; Interleukin 6; Sepsis

Indexed keywords

COBROTOXIN; COMPLEMENT COMPONENT C5A; INTERLEUKIN 6; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEREMIA; COMPLEMENT ACTIVATION; COMPLEMENT INHIBITION; CONTROLLED STUDY; ESCHERICHIA COLI; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; SEPSIS; SEPTIC SHOCK; SWINE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; COBRA VENOMS; COMPLEMENT C5A; DISEASE MODELS, ANIMAL; INTERLEUKIN-6; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; SHOCK, SEPTIC; SWINE;

EID: 0029980816     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830260522     Document Type: Article

References (31)

1. Goldstein, I. M., in Gallin, J. I., Goldstein, I. M. and Snyderman, R. (Eds.), Inflammation: Basic principles and clinical correlates, 2nd ed., Raven Press, New York 1992, p. 63.
2. Hoffmann, T., Böttger, E. C., Baum, H. P., Dennebaum, R., Hadding, U. and Bitter-Suermann, D., Eur. J. Clin. Invest. 1986. 16: 500.
3. Stevens, J. H., O'Hanley, P., Shapiro, J. M., Mihm, F. G., Satoh, P. S., Collins, J. A. and Raffin, T. A., J. Clin. Invest. 1986. 77: 1812.
4. Smedegard, G., Cui, L. X. and Hugli, T. E., Am. J. Pathol. 1989. 135: 489.
5. Schindler, R., Gelfand, J. A. and Dinarello, C. A., Blood 1990. 76: 1631.
6. Scholz, W., McClurg, M. R., Cardenas, G. J., Smith, M., Noonan, D. J., Hugli, T. E. and Morgan, E. L., Clin. Immunol. Immunopathol. 1990. 57; 297.
7. Cavaillon, J. M., Fitting, C. and Haeffner-Cavaillon, N., Eur. J. Immunol. 1990. 20: 253.
8. Montz, H., Koch, K. C., Zierz, R. and Götze, O., Immunology 1991. 74: 373.
9. Ember, J. A., Sanderson, S. D., Hugli, T. E. and Morgan, E. L., Am. J. Pathol. 1994. 144: 393.
10. Gerard, C. and Hugli, T. E., J. Biol. Chem. 1980. 255: 4710.
11. Oppermann, M., Raedt, U., Hebell, T., Schmidt, B., Zimmermann, B. and Götze, O., J. Immunol. 1993. 151: 3785.
12. Vogel, C. W. and Müller-Eberhard, H. J., J. Immunol. Methods 1984. 73: 203.
13. Montz, H., Fuhrmann, A., Schulze, M. and Götze, O., Cell. Immunol. 1990. 127; 337.
14. Merritt, J. E., McCarthy, S. A., Davies, M. P. and Moores, K. E., Biochem. J. 1990. 269: 513.
15. Aarden, L. A., De Groot, E. R., Schaap, O. L. and Lansdorp, P. M., Eur. J. Immunol. 1987. 17: 1411.
16. Oppermann, M., Höpken, U. and Götze, O., Immunopharm. 1992. 24: 119.
17. Jagels, M. A. and Hugli, T. E., J. Immunol. 1992. 148: 1119.
18. Billiau, A. and Vandekerckhove, F., Eur. J. Clin. Invest. 1991. 21: 559.
19. Haeffner-Cavaillon, N., Cavaillon, J. M., Laude, M., Kazatchkine, M. D., J. Immunol. 1987. 139: 794.
20. Daniels, R. H., Houston, W. A., Petersen, M. M., Williams, J. D., Williams, B. D. and Morgan, B. P., Immunology 1990. 69: 237.
21. Rosenberg, L. T. and Tachibana, D. K., Prog. Allergy 1986. 39: 169.
22. Hellewell, P. G., Jose, P. J. and Williams, T. J., Br. J. Pharmacol. 1992. 107: 1163.
23. Amsterdam, E. A., Stahl, G. L., Pan, H. L., Rendig, S. V., Fletcher, M. P. and Longhurst, J. C., Am. J. Physiol. 1995. 268: H448.
24. Morgan, E. L., Sanderson, S., Scholz, W., Noonan, D. J., Weigle, W. O. and Hugli, T. E., J. Immunol. 1992. 148: 3937.
25. Gross, V. and Andus, T., Eur. J. Clin. Invest. 1992. 22: 271.
26. Libert, C., Vink, A., Coulie, P., Brouckaert, P., Everaedt, B., Van Snick, J. and Fiers, W., Eur. J. Immunol. 1992. 22: 2625.
27. Starnes, H. F., Pearce, M. K., Tewari, A., Yim, J. H., Zou, J. C. and Abrams, J. S., J. Immunol. 1990. 145: 4185.
28. Akira, S., Taga, T. and Kishimoto, T., Adv. Immunol. 1993. 54: 1.
29. Kaspar, R. L. and Gehrke, L., J. Immunol. 1994. 153: 277.
30. Barton, P. A. and Warren, J. S., Infect. Immun. 1993. 61: 1474.
31. Schindler, R., Linnenweber, S., Schulze, M., Oppermann, M., Dinarello, C. A., Shaldon, S. and Koch, K. M., Kidney Int. 1993. 43: 712.