Cellular distribution and cellular reactivity of platinum(II) complexes

Biochemical Pharmacology

Volumn 52, Issue 1, 1996, Pages 7-14

  Lindauer, Elfriede ^a   Holler, Eggehard ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

chemotherapy; cisplatin; platinum DNA; platinum metabolism; prodrug activation; reactive platinum

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; CISPLATIN; DNA; K 104; PLATINUM; PLATINUM COMPLEX; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CATTLE; CELL LEVEL; CELL NUCLEUS; CELL STRAIN MCF 7; CELLULAR DISTRIBUTION; CHROMOSOME; CONTROLLED STUDY; DNA ADDUCT; DNA BINDING; DNA REPAIR; DRUG ACCUMULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; THYMUS;

EID: 0029980814     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00106-2     Document Type: Article

References (14)

1. Holler E, Mechanism of action of tumor-inhibiting metal complexes. In: Metal Complexes in Cancer Chemotherapy (Ed. Keppler B), pp. 37-71. VCH Verlagsgesellschaft, Weinheim, Germany, 1993.
2. Otto AM, Faderl M and Schönenberger H, Dissociation of estrogenic and cytotoxic properties of an estrogen receptor-binding platinum complex in human breast cancer cell lines. Cancer Res 51: 3217-3223, 1991.
3. Reile H, Bernhardt G, Koch M, Schönenberger H, Holstein M and Lux F, Chemosensitivity of human MCF-7 breast cancer cells to diastereomeric diaqua(1,2-diphenylethylenedimaine)platinum(II) sulfates and specific platinum accumulation. Cancer Chemo Pharmacol 30: 113-122, 1992.
4. Fichtinger-Schepman AMJ, van Oosterom AT, Lohman PHM and Berends F, cis-Diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients: Quantitative immunochemical detection of the adduct induction and removal after a single dose of cis-diamminedichloroplatinum(II). Cancer Res 47: 3000-3004, 1987.
5. Thomas PS and Farquhar MN, Specific measurements of DNA in nuclei and nucleic acids using diaminobenzoic acid. Analytical Biochem 89: 35-44, 1978.
6. Bannister SJ, Sternson LA and Repta AJ, Urine analysis of platinum species derived from cis-dichlorodiammineplatinum(II) by high-performance liquid chromatography following derivatization with sodium diethyldithiocarbamate. J Chromatography 173: 333-342, 1979.
7. Meyer T, Koop R, von Angerer E, Schönenberger H and Holler E, A rapid luciferase transfection assay for transcription activation effects and stability control of estrogenic drugs in cell cultures. J Cancer Res Clin Oncol 120: 359-364, 1994.
8. Dedon PC and Borch RF, Characterization of the reactions of platinum antitumor agents with biologic and nonbiologic sulfur-containing nucleophiles. Biochem Pharmacol 36: 1955-1964, 1987.
9. Bernges F and Holler E, Ring-substituted diaqua(1,2-diphenylethylenediamine)platinum (II) sulfate reacts with DNA through a dissociable complex. Eur J Biochem 208: 573-579, 1992.
10. Reile H, Müller R, Gust R, Laske R, Krischke W, Bernhardt G, Spruß T, Jennerwein M, Engel J, Seeber S, Osieka R and Schönenberger H, Tumor inhibiting [1,2-bis(fluorophenyl)-ethylenediamine]platinum(II) complexes. Arch Pharm (Weinheim) 323: 133-140 (1990).
11. Andrews PA, Wung WE and Howell SB, A high-performance liquid chromatography assay with improved selectivity for cisplatin and active platinum(II)-complexes in plasma ultrafiltrate. Anal Biochemistry 143: 46-56, 1984.
12. Fournier C, Vennin P and Hecquec B, Correlation between free platinum AUC and total platinum measurement 24 h after i.v. bolus injection of cisplatin in humans. Cancer Chemother Pharmacol 21: 75-77, 1988.
13. Roberts JJ, Knox RJ, Friedlos F and Lydall DA, DNA as the target for the cytotoxic and antitumor action of platinum coordination complexes: comparative in vitro and in vivo studies of cisplatin and carboplatin. In: Biochemical Mechanisms of Platinum Antitumor Drugs (Ed. McBrien DCH and Slater TF), pp. 29-64. IRL Press, Oxford, 1986.
14. Yoshida M, Khokhar AR and Siddik ZH, Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines. Cancer Res 54: 3468-3473, 1994.