Alloantibody and intragraft cellular response to MHC class I-disparate kidney allografts in recipients tolerized by donor-specific transfusion and cyclosporine

Transplantation

Volumn 62, Issue 1, 1996, Pages 23-29

  Tweedle, James R ^a   Middleton, Sheena E ^a   Marshall, Hilary E ^a   Bradley, J Andrew ^a   Bolton, Eleanor M ^a,b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b WESTERN INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; CYCLOSPORIN; MAJOR HISTOCOMPATIBILITY ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; CLONAL ANERGY; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; KIDNEY ALLOGRAFT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; RECIPIENT; TRANSFUSION;

ANIMALS; BASE SEQUENCE; BLOOD TRANSFUSION; CYCLOSPORINE; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; DNA PRIMERS; GENE EXPRESSION; GRAFT REJECTION; HISTOCOMPATIBILITY; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; ISOANTIBODIES; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MOLECULAR SEQUENCE DATA; RATS; RATS, INBRED STRAINS; RNA, MESSENGER; TISSUE DONORS;

EID: 0029980795     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199607150-00005     Document Type: Article

References (40)

1. Hall BM. Cells mediating allograft rejection. Transplantation 1991; 51: 1141.
2. Bradley JA, Bolton EM. The T cell requirements for allograft rejection. Transplant Rev 1992; 6: 115.
3. Halloran PF, Schlaut J, Solez K, Srinivasa NS. The significance of the anti-class I response: II. Clinical and pathologic features of renal transplants with anti-class I-like antibody. Transplantation 1992; 53: 550.
4. Grade JA, Bolton EM, Porteous C, Bradley JA. T cell requirements for the rejection of renal allografts bearing an isolated class I MHC disparity. J Exp Med 1990; 172: 1547.
5. + T cell-mediated rejection of major histocompatibility complex class I-disparate grafts: a role for alloantibody. Eur J Immunol 1993; 23: 2078.
6. Opelz G, Sengar DPS, Mickey MR, Terasaki PI. Effect of blood transfusions on subsequent kidney transplants. Transplant Proc 1973; 5: 253.
7. Opelz G, Terasaki PI. Poor kidney transplant survival in recipients with frozen blood transfusions or no transfusions. Lancet 1974; 2: 696.
8. Salvatierra O, McVicar J, Melzer J, et al. Improved results with combined donor-specific transfusion (DST) and sequential therapy protocol. Transplant Proc 1991; 23: 1024.
9. Fabre JW, Morris PJ. The effect of donor strain blood pretreatment on renal allograft rejection in rats. Transplantation 1972; 14: 608.
10. Marquet RL, Heystek GA. Induction of suppressor cells by donor-specific blood transfusions and heart transplantation in rats. Transplantation 1981; 31: 272.
11. Dallman MJ, Wood KJ, Morris PJ. Specific cytotoxic T cells are found in the non-rejected kidneys of blood transfused rats. J Exp Med 1987; 165: 566.
12. Armstrong HE, Bolton EM, McMillan I, Spencer SC, Bradley JA. Prolonged survival of actively enhanced rat renal allografts despite accelerated cellular infiltration and rapid induction of both class I and class II MHC antigens. J Exp Med 1987; 165: 891.
13. Qigley RL, Wood KJ, Morris PJ. Transfusion induces blood donor-specific suppressor cells. J Immunol 1989; 142: 463.
14. Downey WE, Baldwin WM, Sanfilippo F. Association of donor-specific blood transfusion enhancement of rat renal allografts with accelerated development of anti-idiotypic antibodies and reduced alloantibody responses. Transplantation 1990. 49: 160.
15. Dallman MJ, Shiho O, Page TH, Wood KJ, Morris PJ. Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway. J Exp Med 1991; 173: 79.
16. Bugeon L, Cuturi M-C, Hallet M-M, Paineau J, Chabannes D, Soulillou J- P. Peripheral tolerance of an allograft in adult rats: characterization by low interleukin-2 and interferon-γ mRNA levels and by strong accumulation of major histocompatibility complex transcripts in the graft. Transplantation 1992; 54: 219.
17. Takeuchi T, Lowry RP, Konieczny B. Heart allografts in murine systems: the differential activation of Th2-like effector cells in peripheral tolerance. Transplantation 1992; 53: 1281.
18. McKnight AJ, Mason DW, Barclay AN. Sequence of rat interleukin 2 and anomalous binding of a mouse interleukin 2 cDNA probe to rat MHC class II-associated invariant chain mRNA. Immunogenetics 1989; 30: 145.
19. McKnight AJ, Barclay AN, Mason DW. Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4+ T cells. Eur J Immunol 1991; 21: 1187.
20. Uberla K, Li W, Qin Z, et al. The rat interleukin-5 gene: characterization and expression by retroviral gene transfer and polymerase chain reaction. Cytokine 1991; 3: 72.
21. Feng L, Tang WW, Chang JCC, Wilson CB. Molecular cloning of rat cytokine synthesis inhibiting factor (IL-10) cDNA and expression in spleen and macrophages. Biochem Biophys Res Commun 1993; 192; 452.
22. Lakkis FG, Cruet EN. Cloning of rat interleukin-13 (IL-13) cDNA and analysis of IL-13 gene expression in experimental glomerulonephritis. Biochem Biophys Res Commun 1993; 197; 612.
23. Dijkema R, Van der Meide PH, Pouwels PH, Caspers M, Dubbeld M, Schellekens H. Cloning and expression of the chromosomal immune interferon gene of the rat. EMBO J 1985; 4: 761.
24. Page TH, Dallman MJ. Molecular cloning of cDNAs for the rat interleukin 2 receptor α and β chain genes: differentially regulated gene activity in response to mitogenic stimulation. Eur J Immunol 1991; 21: 2133.
25. Nudel U, Zakut R, Shani M, Neuman S, Levy Z, Yaffe D. The nucleotide sequence of the rat cytoplasmic beta-actin gene. Nucleic Acids Res 1983; 11: 1759.
26. Cunningham C, Power DA, Stewart KN, Catto GRD. The influence of cyclosporin A on alloantibody responses in inbred rats: provisional evidence for a serum factor with antiidiotypic activity. Clin Exp Immunol 1988; 72: 130.
27. Tchervenkov JI, Epstein MD, Alexander JW, Schroeder TJ. The effect of donor-specific blood transfusion, cyclosporine, and dietary prostaglandin precursors on rat cardiac allograft survival: II. Effectiveness of a 24-hour induction period with DST and CsA in inducing long-term graft survival. Transplantation 1989; 47: 177.
28. Patterson DJ, Jefferies WA, Green JR, et al. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol Immunol 1987; 24: 1281.
29. Siegling A, Lehmann M, Riedel H, et al. A nondepleting anti-rat CD4 monoclonal antibody that suppresses T helper 1-like but not T helper 2-like intragraft lymphokine secretion induces long-term survival of renal allografts. Transplantation 1993; 57: 464.
30. Ferraresso M, Tian L, Ghobrial R, Stepkowski SM, Kahan BD. Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats. J Immunol 1994; 153: 3307.
31. Chen N, Field EH. Enhanced type 2 and diminished type 1 cytokines in neonatal tolerance. Transplantation 1995; 59: 933.
32. Hancock WW, Sayegh MH, Sablinski T, Kut JP, Kupiec-Weglinski JW, Milford EL. Blocking of mononuclear cell accumulation, cytokine production and endothelial activation within rat cardiac allografts by CD4 monoclonal antibody therapy. Transplantation 1992; 53: 1276.
33. Granelli-Piperno A. Lymphokine gene expression in vivo is inhibited by cyclosporin A. J Exp Med 1990; 171: 533.
34. Gajewski TF, Schell SR, Fitch FW. Evidence implicating utilization of different T cell receptor-associated signaling pathways by Th1 and Th2 clones. J Immunol 1990; 144: 4110.
35. Durez P, Abramowicz D, Gerard C, et al. In vivo induction of interleukin 10 by anti-CD3 monoclonal antibody or bacterial lipopolysaccharide: differential modulation by cyclosporin A. J Exp Med 1993; 177: 551.
36. Broski AP, Halloran PF. Tissue distribution of IL-10 mRNA in normal mice: evidence that a component of IL-10 expression is T and B cell-independent and increased by irradiation. Transplantation 1994; 57: 582.
37. Plaut M, Pierce JH, Watson CJ, Hanley-Hyde J, Nordan RP, Paul WE. Mast cell lines produce lymphokines in response to cross-linkage of Fc∈R1 or to calcium ionophores. Nature 1989; 339: 64.
38. Paul WE, Ohara J. B cell stimulatory factor-1/interleukin 4. Annu Rev Immunol 1987; 5: 429.
39. Defrance T, Vanbervliet B, Briere F, Durond I, Rousset I, Banchereau J. Interleukin 10 and transforming growth factor β cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med 1992; 175: 671.
40. Punnonen J, Aversa G, Locks BG, et al. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci USA 1993; 90: 3730.